| Full name: Rho guanine nucleotide exchange factor 33 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p22.1 | ||
| Entrez ID: 100271715 | HGNC ID: HGNC:37252 | Ensembl Gene: ENSG00000214694 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGEF33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGEF33 | 100271715 | 1556881_at | -0.1065 | 0.6717 | |
| GSE26886 | ARHGEF33 | 100271715 | 1556881_at | 0.0197 | 0.8534 | |
| GSE45670 | ARHGEF33 | 100271715 | 1556881_at | 0.0043 | 0.9608 | |
| GSE53622 | ARHGEF33 | 100271715 | 76805 | 0.2077 | 0.3159 | |
| GSE53624 | ARHGEF33 | 100271715 | 76805 | 0.3414 | 0.1121 | |
| GSE63941 | ARHGEF33 | 100271715 | 1556881_at | -0.0379 | 0.8272 | |
| GSE77861 | ARHGEF33 | 100271715 | 1556881_at | 0.0785 | 0.3708 | |
| GSE97050 | ARHGEF33 | 100271715 | A_33_P3269670 | 0.0819 | 0.7799 | |
| SRP133303 | ARHGEF33 | 100271715 | RNAseq | -0.5869 | 0.0556 | |
| SRP159526 | ARHGEF33 | 100271715 | RNAseq | 1.1994 | 0.0370 | |
| SRP219564 | ARHGEF33 | 100271715 | RNAseq | -0.6173 | 0.3504 | |
| TCGA | ARHGEF33 | 100271715 | RNAseq | -0.2960 | 0.4129 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ARHGEF33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGEF33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGEF33 | 100271715 | 11 | 1 | 18 | |
| GSE20123 | ARHGEF33 | 100271715 | 9 | 1 | 20 | |
| GSE43470 | ARHGEF33 | 100271715 | 3 | 0 | 40 | |
| GSE46452 | ARHGEF33 | 100271715 | 1 | 4 | 54 | |
| GSE47630 | ARHGEF33 | 100271715 | 7 | 0 | 33 | |
| GSE54993 | ARHGEF33 | 100271715 | 0 | 5 | 65 | |
| GSE54994 | ARHGEF33 | 100271715 | 10 | 0 | 43 | |
| GSE60625 | ARHGEF33 | 100271715 | 0 | 3 | 8 | |
| GSE74703 | ARHGEF33 | 100271715 | 3 | 0 | 33 | |
| GSE74704 | ARHGEF33 | 100271715 | 9 | 1 | 10 | |
| TCGA | ARHGEF33 | 100271715 | 35 | 2 | 59 |
Total number of gains: 88; Total number of losses: 17; Total Number of normals: 383.
Somatic mutations of ARHGEF33:
Generating mutation plots.
Highly correlated genes for ARHGEF33:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGEF33 | OR2AT4 | 0.804886 | 3 | 0 | 3 |
| ARHGEF33 | KRTAP19-2 | 0.783408 | 3 | 0 | 3 |
| ARHGEF33 | ZNF546 | 0.765415 | 4 | 0 | 4 |
| ARHGEF33 | TP53AIP1 | 0.762036 | 3 | 0 | 3 |
| ARHGEF33 | CALY | 0.76173 | 4 | 0 | 4 |
| ARHGEF33 | RBM20 | 0.761043 | 3 | 0 | 3 |
| ARHGEF33 | OR2T33 | 0.75921 | 3 | 0 | 3 |
| ARHGEF33 | MRPL33 | 0.752934 | 3 | 0 | 3 |
| ARHGEF33 | TMEM181 | 0.752469 | 3 | 0 | 3 |
| ARHGEF33 | ZNF248 | 0.751626 | 4 | 0 | 4 |
| ARHGEF33 | SOX5 | 0.74877 | 3 | 0 | 3 |
| ARHGEF33 | KIR3DL2 | 0.746538 | 3 | 0 | 3 |
| ARHGEF33 | AKAP6 | 0.746177 | 3 | 0 | 3 |
| ARHGEF33 | ZNF638 | 0.744958 | 3 | 0 | 3 |
| ARHGEF33 | LRCH3 | 0.740365 | 3 | 0 | 3 |
| ARHGEF33 | KRTAP10-4 | 0.734302 | 3 | 0 | 3 |
| ARHGEF33 | PPP5C | 0.730341 | 3 | 0 | 3 |
| ARHGEF33 | MAP1LC3B | 0.729747 | 3 | 0 | 3 |
| ARHGEF33 | OR7G1 | 0.727686 | 3 | 0 | 3 |
| ARHGEF33 | ZNF583 | 0.726149 | 3 | 0 | 3 |
For details and further investigation, click here
