| Full name: zinc finger protein 638 | Alias Symbol: NP220|MGC26130|Zfp638 | ||
| Type: protein-coding gene | Cytoband: 2p13.3-p13.2 | ||
| Entrez ID: 27332 | HGNC ID: HGNC:17894 | Ensembl Gene: ENSG00000075292 | OMIM ID: 614349 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF638:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF638 | 27332 | 211257_x_at | -0.0488 | 0.9228 | |
| GSE20347 | ZNF638 | 27332 | 211257_x_at | 0.2753 | 0.0189 | |
| GSE23400 | ZNF638 | 27332 | 211257_x_at | 0.2574 | 0.0000 | |
| GSE26886 | ZNF638 | 27332 | 211257_x_at | 0.3396 | 0.0855 | |
| GSE29001 | ZNF638 | 27332 | 211257_x_at | 0.2447 | 0.5342 | |
| GSE38129 | ZNF638 | 27332 | 211257_x_at | 0.2270 | 0.0135 | |
| GSE45670 | ZNF638 | 27332 | 211257_x_at | 0.0246 | 0.8802 | |
| GSE53622 | ZNF638 | 27332 | 79271 | 0.2157 | 0.0038 | |
| GSE53624 | ZNF638 | 27332 | 79271 | 0.0991 | 0.4093 | |
| GSE63941 | ZNF638 | 27332 | 211257_x_at | -0.5892 | 0.1217 | |
| GSE77861 | ZNF638 | 27332 | 211257_x_at | 0.2172 | 0.1183 | |
| GSE97050 | ZNF638 | 27332 | A_24_P3140 | -0.1150 | 0.7423 | |
| SRP007169 | ZNF638 | 27332 | RNAseq | 0.8108 | 0.0172 | |
| SRP008496 | ZNF638 | 27332 | RNAseq | 0.9393 | 0.0001 | |
| SRP064894 | ZNF638 | 27332 | RNAseq | 0.0235 | 0.8830 | |
| SRP133303 | ZNF638 | 27332 | RNAseq | 0.2055 | 0.0637 | |
| SRP159526 | ZNF638 | 27332 | RNAseq | 0.3378 | 0.2268 | |
| SRP193095 | ZNF638 | 27332 | RNAseq | 0.0128 | 0.8747 | |
| SRP219564 | ZNF638 | 27332 | RNAseq | 0.1057 | 0.7395 | |
| TCGA | ZNF638 | 27332 | RNAseq | -0.0455 | 0.2950 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF638 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF638:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF638 | 27332 | 11 | 1 | 18 | |
| GSE20123 | ZNF638 | 27332 | 11 | 1 | 18 | |
| GSE43470 | ZNF638 | 27332 | 3 | 0 | 40 | |
| GSE46452 | ZNF638 | 27332 | 2 | 3 | 54 | |
| GSE47630 | ZNF638 | 27332 | 7 | 0 | 33 | |
| GSE54993 | ZNF638 | 27332 | 0 | 6 | 64 | |
| GSE54994 | ZNF638 | 27332 | 11 | 0 | 42 | |
| GSE60625 | ZNF638 | 27332 | 0 | 3 | 8 | |
| GSE74703 | ZNF638 | 27332 | 3 | 0 | 33 | |
| GSE74704 | ZNF638 | 27332 | 9 | 0 | 11 | |
| TCGA | ZNF638 | 27332 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of ZNF638:
Generating mutation plots.
Highly correlated genes for ZNF638:
Showing top 20/524 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF638 | HPS5 | 0.817228 | 3 | 0 | 3 |
| ZNF638 | ZNF546 | 0.802574 | 3 | 0 | 3 |
| ZNF638 | FAM161B | 0.800845 | 3 | 0 | 3 |
| ZNF638 | GCC2 | 0.792078 | 3 | 0 | 3 |
| ZNF638 | CCNC | 0.750928 | 3 | 0 | 3 |
| ZNF638 | ZNF878 | 0.746977 | 3 | 0 | 3 |
| ZNF638 | ARHGEF33 | 0.744958 | 3 | 0 | 3 |
| ZNF638 | ZNF121 | 0.741255 | 3 | 0 | 3 |
| ZNF638 | TOM1L1 | 0.734173 | 3 | 0 | 3 |
| ZNF638 | C2orf69 | 0.733844 | 3 | 0 | 3 |
| ZNF638 | ZNF225 | 0.728895 | 4 | 0 | 3 |
| ZNF638 | RPF2 | 0.728067 | 3 | 0 | 3 |
| ZNF638 | LDLRAD3 | 0.722706 | 3 | 0 | 3 |
| ZNF638 | ZNF735 | 0.714936 | 3 | 0 | 3 |
| ZNF638 | DDX59 | 0.707039 | 4 | 0 | 4 |
| ZNF638 | RBMS1 | 0.706151 | 4 | 0 | 4 |
| ZNF638 | ZNF208 | 0.699464 | 3 | 0 | 3 |
| ZNF638 | OR2AT4 | 0.699221 | 3 | 0 | 3 |
| ZNF638 | CNOT2 | 0.698991 | 4 | 0 | 4 |
| ZNF638 | RIOK2 | 0.693731 | 3 | 0 | 3 |
For details and further investigation, click here
