| Full name: zinc finger protein 461 | Alias Symbol: GIOT-1|MGC33911 | ||
| Type: protein-coding gene | Cytoband: 19q13.13 | ||
| Entrez ID: 92283 | HGNC ID: HGNC:21629 | Ensembl Gene: ENSG00000197808 | OMIM ID: 608640 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF461:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF461 | 92283 | 232391_at | -0.0980 | 0.7886 | |
| GSE26886 | ZNF461 | 92283 | 232391_at | -0.0175 | 0.8903 | |
| GSE45670 | ZNF461 | 92283 | 232391_at | 0.0110 | 0.9378 | |
| GSE53622 | ZNF461 | 92283 | 5668 | 0.0599 | 0.6723 | |
| GSE53624 | ZNF461 | 92283 | 5668 | 0.1256 | 0.4281 | |
| GSE63941 | ZNF461 | 92283 | 232391_at | -0.0022 | 0.9901 | |
| GSE77861 | ZNF461 | 92283 | 232391_at | 0.0873 | 0.4733 | |
| GSE97050 | ZNF461 | 92283 | A_33_P3269278 | -0.2348 | 0.2450 | |
| SRP007169 | ZNF461 | 92283 | RNAseq | -0.0040 | 0.9950 | |
| SRP064894 | ZNF461 | 92283 | RNAseq | 0.2837 | 0.2192 | |
| SRP133303 | ZNF461 | 92283 | RNAseq | 0.0273 | 0.8605 | |
| SRP159526 | ZNF461 | 92283 | RNAseq | -0.0836 | 0.8660 | |
| SRP193095 | ZNF461 | 92283 | RNAseq | -0.1240 | 0.2643 | |
| SRP219564 | ZNF461 | 92283 | RNAseq | -0.2138 | 0.4778 | |
| TCGA | ZNF461 | 92283 | RNAseq | -0.3601 | 0.0316 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF461 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF461:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF461 | 92283 | 8 | 4 | 18 | |
| GSE20123 | ZNF461 | 92283 | 8 | 3 | 19 | |
| GSE43470 | ZNF461 | 92283 | 3 | 8 | 32 | |
| GSE46452 | ZNF461 | 92283 | 47 | 2 | 10 | |
| GSE47630 | ZNF461 | 92283 | 9 | 5 | 26 | |
| GSE54993 | ZNF461 | 92283 | 17 | 3 | 50 | |
| GSE54994 | ZNF461 | 92283 | 6 | 9 | 38 | |
| GSE60625 | ZNF461 | 92283 | 9 | 0 | 2 | |
| GSE74703 | ZNF461 | 92283 | 3 | 5 | 28 | |
| GSE74704 | ZNF461 | 92283 | 7 | 1 | 12 | |
| TCGA | ZNF461 | 92283 | 22 | 10 | 64 |
Total number of gains: 139; Total number of losses: 50; Total Number of normals: 299.
Somatic mutations of ZNF461:
Generating mutation plots.
Highly correlated genes for ZNF461:
Showing top 20/114 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF461 | ZNF547 | 0.889063 | 3 | 0 | 3 |
| ZNF461 | ZNF878 | 0.884876 | 3 | 0 | 3 |
| ZNF461 | ZNF416 | 0.842738 | 3 | 0 | 3 |
| ZNF461 | ZNF676 | 0.824275 | 3 | 0 | 3 |
| ZNF461 | ZNF263 | 0.808813 | 3 | 0 | 3 |
| ZNF461 | ZNF816 | 0.804116 | 3 | 0 | 3 |
| ZNF461 | ZNF546 | 0.773943 | 4 | 0 | 3 |
| ZNF461 | ZNF721 | 0.769416 | 3 | 0 | 3 |
| ZNF461 | ZNF735 | 0.762798 | 3 | 0 | 3 |
| ZNF461 | ZNF585A | 0.761704 | 4 | 0 | 3 |
| ZNF461 | KIAA0753 | 0.761558 | 3 | 0 | 3 |
| ZNF461 | ABL1 | 0.749961 | 3 | 0 | 3 |
| ZNF461 | ZNF614 | 0.749709 | 4 | 0 | 4 |
| ZNF461 | CHD3 | 0.738455 | 3 | 0 | 3 |
| ZNF461 | PKIG | 0.737298 | 3 | 0 | 3 |
| ZNF461 | GRIN3A | 0.736364 | 3 | 0 | 3 |
| ZNF461 | RC3H1 | 0.735808 | 3 | 0 | 3 |
| ZNF461 | KRTAP21-2 | 0.734837 | 3 | 0 | 3 |
| ZNF461 | MRVI1 | 0.724346 | 3 | 0 | 3 |
| ZNF461 | LCE1E | 0.720553 | 3 | 0 | 3 |
For details and further investigation, click here
