| Full name: zinc finger protein 708 | Alias Symbol: KOX8 | ||
| Type: protein-coding gene | Cytoband: 19p12 | ||
| Entrez ID: 7562 | HGNC ID: HGNC:12945 | Ensembl Gene: ENSG00000182141 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF708:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF708 | 7562 | 239482_x_at | 0.1399 | 0.8512 | |
| GSE26886 | ZNF708 | 7562 | 239482_x_at | 0.1715 | 0.3176 | |
| GSE45670 | ZNF708 | 7562 | 239482_x_at | -0.3634 | 0.1319 | |
| GSE63941 | ZNF708 | 7562 | 239482_x_at | -1.4128 | 0.0010 | |
| GSE77861 | ZNF708 | 7562 | 239482_x_at | -0.0875 | 0.5138 | |
| SRP007169 | ZNF708 | 7562 | RNAseq | 0.0102 | 0.9851 | |
| SRP008496 | ZNF708 | 7562 | RNAseq | 0.1996 | 0.6163 | |
| SRP064894 | ZNF708 | 7562 | RNAseq | -0.3226 | 0.2405 | |
| SRP133303 | ZNF708 | 7562 | RNAseq | -0.4495 | 0.0227 | |
| SRP159526 | ZNF708 | 7562 | RNAseq | -0.6459 | 0.0222 | |
| SRP193095 | ZNF708 | 7562 | RNAseq | -0.3337 | 0.0868 | |
| SRP219564 | ZNF708 | 7562 | RNAseq | -0.3638 | 0.3389 | |
| TCGA | ZNF708 | 7562 | RNAseq | -0.5332 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF708 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNF708:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF708 | 7562 | 4 | 5 | 21 | |
| GSE20123 | ZNF708 | 7562 | 4 | 3 | 23 | |
| GSE43470 | ZNF708 | 7562 | 2 | 6 | 35 | |
| GSE46452 | ZNF708 | 7562 | 47 | 1 | 11 | |
| GSE47630 | ZNF708 | 7562 | 7 | 7 | 26 | |
| GSE54993 | ZNF708 | 7562 | 17 | 3 | 50 | |
| GSE54994 | ZNF708 | 7562 | 6 | 13 | 34 | |
| GSE60625 | ZNF708 | 7562 | 9 | 0 | 2 | |
| GSE74703 | ZNF708 | 7562 | 2 | 4 | 30 | |
| GSE74704 | ZNF708 | 7562 | 1 | 3 | 16 | |
| TCGA | ZNF708 | 7562 | 17 | 13 | 66 |
Total number of gains: 116; Total number of losses: 58; Total Number of normals: 314.
Somatic mutations of ZNF708:
Generating mutation plots.
Highly correlated genes for ZNF708:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF708 | ZNF738 | 0.723098 | 5 | 0 | 4 |
| ZNF708 | ZNF320 | 0.706288 | 4 | 0 | 4 |
| ZNF708 | TOP2B | 0.700584 | 3 | 0 | 3 |
| ZNF708 | ZNF675 | 0.697661 | 3 | 0 | 3 |
| ZNF708 | ZNF468 | 0.677814 | 4 | 0 | 4 |
| ZNF708 | ZNF93 | 0.672883 | 3 | 0 | 3 |
| ZNF708 | ZNF709 | 0.670276 | 4 | 0 | 4 |
| ZNF708 | ZNF813 | 0.667294 | 4 | 0 | 3 |
| ZNF708 | ZNF43 | 0.667114 | 4 | 0 | 4 |
| ZNF708 | SHPRH | 0.664832 | 4 | 0 | 3 |
| ZNF708 | EI24 | 0.657483 | 3 | 0 | 3 |
| ZNF708 | ZNF443 | 0.656932 | 5 | 0 | 3 |
| ZNF708 | TMEM168 | 0.655765 | 3 | 0 | 3 |
| ZNF708 | ZNF83 | 0.648894 | 4 | 0 | 3 |
| ZNF708 | ZNF420 | 0.648274 | 5 | 0 | 5 |
| ZNF708 | ZNF736 | 0.647006 | 3 | 0 | 3 |
| ZNF708 | ZNF100 | 0.645053 | 5 | 0 | 4 |
| ZNF708 | ZNF506 | 0.641232 | 5 | 0 | 4 |
| ZNF708 | SLC25A40 | 0.638963 | 3 | 0 | 3 |
| ZNF708 | GNL3 | 0.638306 | 3 | 0 | 3 |
For details and further investigation, click here
