| Full name: transmembrane protein 168 | Alias Symbol: DKFZp564C012|FLJ13576 | ||
| Type: protein-coding gene | Cytoband: 7q31.1 | ||
| Entrez ID: 64418 | HGNC ID: HGNC:25826 | Ensembl Gene: ENSG00000146802 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM168:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM168 | 64418 | 218962_s_at | 0.0239 | 0.9779 | |
| GSE20347 | TMEM168 | 64418 | 218962_s_at | -0.3056 | 0.0560 | |
| GSE23400 | TMEM168 | 64418 | 218962_s_at | -0.1099 | 0.1994 | |
| GSE26886 | TMEM168 | 64418 | 218962_s_at | -0.3100 | 0.2253 | |
| GSE29001 | TMEM168 | 64418 | 218962_s_at | -0.2067 | 0.5722 | |
| GSE38129 | TMEM168 | 64418 | 218962_s_at | -0.0851 | 0.6206 | |
| GSE45670 | TMEM168 | 64418 | 218962_s_at | -0.2805 | 0.1159 | |
| GSE53622 | TMEM168 | 64418 | 17189 | -0.3396 | 0.0006 | |
| GSE53624 | TMEM168 | 64418 | 17189 | -0.4266 | 0.0000 | |
| GSE63941 | TMEM168 | 64418 | 218962_s_at | -0.5796 | 0.2307 | |
| GSE77861 | TMEM168 | 64418 | 218962_s_at | -0.3516 | 0.2780 | |
| GSE97050 | TMEM168 | 64418 | A_24_P414952 | 0.0461 | 0.8301 | |
| SRP007169 | TMEM168 | 64418 | RNAseq | -0.5079 | 0.1423 | |
| SRP008496 | TMEM168 | 64418 | RNAseq | -0.2865 | 0.0705 | |
| SRP064894 | TMEM168 | 64418 | RNAseq | -0.5053 | 0.0009 | |
| SRP133303 | TMEM168 | 64418 | RNAseq | -0.3046 | 0.0231 | |
| SRP159526 | TMEM168 | 64418 | RNAseq | -0.7564 | 0.0023 | |
| SRP193095 | TMEM168 | 64418 | RNAseq | -0.4209 | 0.0024 | |
| SRP219564 | TMEM168 | 64418 | RNAseq | -0.4191 | 0.2811 | |
| TCGA | TMEM168 | 64418 | RNAseq | -0.0655 | 0.3601 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM168 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM168:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM168 | 64418 | 10 | 2 | 18 | |
| GSE20123 | TMEM168 | 64418 | 11 | 2 | 17 | |
| GSE43470 | TMEM168 | 64418 | 5 | 2 | 36 | |
| GSE46452 | TMEM168 | 64418 | 8 | 1 | 50 | |
| GSE47630 | TMEM168 | 64418 | 7 | 4 | 29 | |
| GSE54993 | TMEM168 | 64418 | 2 | 8 | 60 | |
| GSE54994 | TMEM168 | 64418 | 12 | 5 | 36 | |
| GSE60625 | TMEM168 | 64418 | 0 | 0 | 11 | |
| GSE74703 | TMEM168 | 64418 | 5 | 2 | 29 | |
| GSE74704 | TMEM168 | 64418 | 7 | 2 | 11 | |
| TCGA | TMEM168 | 64418 | 36 | 16 | 44 |
Total number of gains: 103; Total number of losses: 44; Total Number of normals: 341.
Somatic mutations of TMEM168:
Generating mutation plots.
Highly correlated genes for TMEM168:
Showing top 20/413 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM168 | NUB1 | 0.736419 | 3 | 0 | 3 |
| TMEM168 | ZNF140 | 0.729806 | 4 | 0 | 3 |
| TMEM168 | ZNF100 | 0.728706 | 3 | 0 | 3 |
| TMEM168 | ZXDA | 0.717987 | 3 | 0 | 3 |
| TMEM168 | DNAJC21 | 0.714373 | 3 | 0 | 3 |
| TMEM168 | GTF2A1 | 0.699234 | 3 | 0 | 3 |
| TMEM168 | YIPF3 | 0.698753 | 4 | 0 | 3 |
| TMEM168 | ABHD16A | 0.697536 | 3 | 0 | 3 |
| TMEM168 | GCC1 | 0.69139 | 4 | 0 | 3 |
| TMEM168 | UBE2N | 0.687044 | 3 | 0 | 3 |
| TMEM168 | ZNF124 | 0.683734 | 3 | 0 | 3 |
| TMEM168 | LTN1 | 0.682073 | 4 | 0 | 4 |
| TMEM168 | PTGER4 | 0.680561 | 3 | 0 | 3 |
| TMEM168 | UNC5CL | 0.675101 | 3 | 0 | 3 |
| TMEM168 | C6orf136 | 0.668493 | 4 | 0 | 3 |
| TMEM168 | ASTE1 | 0.665898 | 4 | 0 | 3 |
| TMEM168 | FAM221A | 0.664514 | 4 | 0 | 4 |
| TMEM168 | ERCC6 | 0.662443 | 4 | 0 | 3 |
| TMEM168 | STAG1 | 0.661142 | 5 | 0 | 5 |
| TMEM168 | ZNF266 | 0.660229 | 4 | 0 | 3 |
For details and further investigation, click here
