| Full name: solute carrier family 25 member 40 | Alias Symbol: MCFP | ||
| Type: protein-coding gene | Cytoband: 7q21.12 | ||
| Entrez ID: 55972 | HGNC ID: HGNC:29680 | Ensembl Gene: ENSG00000075303 | OMIM ID: 610821 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC25A40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A40 | 55972 | 227012_at | 0.3340 | 0.6186 | |
| GSE20347 | SLC25A40 | 55972 | 205716_at | 0.0265 | 0.7766 | |
| GSE23400 | SLC25A40 | 55972 | 205716_at | 0.1079 | 0.0005 | |
| GSE26886 | SLC25A40 | 55972 | 227012_at | 0.3560 | 0.1420 | |
| GSE29001 | SLC25A40 | 55972 | 205716_at | -0.1651 | 0.3722 | |
| GSE38129 | SLC25A40 | 55972 | 205716_at | 0.1705 | 0.1307 | |
| GSE45670 | SLC25A40 | 55972 | 227012_at | -0.0312 | 0.8811 | |
| GSE53622 | SLC25A40 | 55972 | 21304 | 0.0931 | 0.3606 | |
| GSE53624 | SLC25A40 | 55972 | 21304 | -0.0970 | 0.2914 | |
| GSE63941 | SLC25A40 | 55972 | 227012_at | 0.4716 | 0.5549 | |
| GSE77861 | SLC25A40 | 55972 | 227012_at | -0.3105 | 0.4352 | |
| GSE97050 | SLC25A40 | 55972 | A_23_P432626 | 0.1664 | 0.5145 | |
| SRP007169 | SLC25A40 | 55972 | RNAseq | -0.2001 | 0.6169 | |
| SRP008496 | SLC25A40 | 55972 | RNAseq | 0.0972 | 0.7981 | |
| SRP064894 | SLC25A40 | 55972 | RNAseq | 0.0708 | 0.7652 | |
| SRP133303 | SLC25A40 | 55972 | RNAseq | 0.3641 | 0.0197 | |
| SRP159526 | SLC25A40 | 55972 | RNAseq | -0.2890 | 0.3032 | |
| SRP193095 | SLC25A40 | 55972 | RNAseq | 0.1532 | 0.1939 | |
| SRP219564 | SLC25A40 | 55972 | RNAseq | 0.3553 | 0.3124 | |
| TCGA | SLC25A40 | 55972 | RNAseq | 0.0663 | 0.4180 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC25A40 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A40 | 55972 | 13 | 1 | 16 | |
| GSE20123 | SLC25A40 | 55972 | 13 | 1 | 16 | |
| GSE43470 | SLC25A40 | 55972 | 5 | 1 | 37 | |
| GSE46452 | SLC25A40 | 55972 | 12 | 0 | 47 | |
| GSE47630 | SLC25A40 | 55972 | 8 | 2 | 30 | |
| GSE54993 | SLC25A40 | 55972 | 2 | 7 | 61 | |
| GSE54994 | SLC25A40 | 55972 | 17 | 2 | 34 | |
| GSE60625 | SLC25A40 | 55972 | 0 | 0 | 11 | |
| GSE74703 | SLC25A40 | 55972 | 4 | 1 | 31 | |
| GSE74704 | SLC25A40 | 55972 | 9 | 1 | 10 | |
| TCGA | SLC25A40 | 55972 | 54 | 4 | 38 |
Total number of gains: 137; Total number of losses: 20; Total Number of normals: 331.
Somatic mutations of SLC25A40:
Generating mutation plots.
Highly correlated genes for SLC25A40:
Showing top 20/434 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A40 | PARG | 0.800384 | 3 | 0 | 3 |
| SLC25A40 | CREBBP | 0.798202 | 3 | 0 | 3 |
| SLC25A40 | GNL3 | 0.797925 | 3 | 0 | 3 |
| SLC25A40 | ACBD5 | 0.784579 | 4 | 0 | 4 |
| SLC25A40 | LUC7L2 | 0.771113 | 3 | 0 | 3 |
| SLC25A40 | LRRC47 | 0.768545 | 3 | 0 | 3 |
| SLC25A40 | NOL9 | 0.768316 | 3 | 0 | 3 |
| SLC25A40 | MRPL37 | 0.766942 | 3 | 0 | 3 |
| SLC25A40 | C10orf55 | 0.749514 | 3 | 0 | 3 |
| SLC25A40 | USP33 | 0.746164 | 3 | 0 | 3 |
| SLC25A40 | ZNF627 | 0.74483 | 4 | 0 | 4 |
| SLC25A40 | MTPAP | 0.742297 | 3 | 0 | 3 |
| SLC25A40 | RCAN3 | 0.740773 | 3 | 0 | 3 |
| SLC25A40 | AGPAT3 | 0.740708 | 3 | 0 | 3 |
| SLC25A40 | CHCHD5 | 0.733397 | 3 | 0 | 3 |
| SLC25A40 | TRUB1 | 0.731037 | 4 | 0 | 4 |
| SLC25A40 | C16orf46 | 0.730714 | 3 | 0 | 3 |
| SLC25A40 | LMBR1 | 0.724063 | 3 | 0 | 3 |
| SLC25A40 | ZNF41 | 0.721141 | 3 | 0 | 3 |
| SLC25A40 | RALGAPA2 | 0.717206 | 3 | 0 | 3 |
For details and further investigation, click here
