| Full name: zinc finger protein 43 | Alias Symbol: HTF6|KOX27 | ||
| Type: protein-coding gene | Cytoband: 19p12 | ||
| Entrez ID: 7594 | HGNC ID: HGNC:13109 | Ensembl Gene: ENSG00000198521 | OMIM ID: 603972 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF43 | 7594 | 206695_x_at | -0.4905 | 0.4939 | |
| GSE20347 | ZNF43 | 7594 | 206695_x_at | -0.2924 | 0.1346 | |
| GSE23400 | ZNF43 | 7594 | 206695_x_at | -0.0823 | 0.1224 | |
| GSE26886 | ZNF43 | 7594 | 206695_x_at | -0.2502 | 0.0979 | |
| GSE29001 | ZNF43 | 7594 | 206695_x_at | -0.2870 | 0.3646 | |
| GSE38129 | ZNF43 | 7594 | 206695_x_at | -0.2441 | 0.1552 | |
| GSE45670 | ZNF43 | 7594 | 206695_x_at | -0.7782 | 0.0013 | |
| GSE53622 | ZNF43 | 7594 | 125073 | -1.3572 | 0.0000 | |
| GSE53624 | ZNF43 | 7594 | 125073 | -0.9008 | 0.0000 | |
| GSE63941 | ZNF43 | 7594 | 206695_x_at | -0.8011 | 0.0225 | |
| GSE77861 | ZNF43 | 7594 | 206695_x_at | -0.2530 | 0.4242 | |
| SRP007169 | ZNF43 | 7594 | RNAseq | -1.5306 | 0.0037 | |
| SRP064894 | ZNF43 | 7594 | RNAseq | -0.1935 | 0.5325 | |
| SRP133303 | ZNF43 | 7594 | RNAseq | -0.3452 | 0.3801 | |
| SRP193095 | ZNF43 | 7594 | RNAseq | -0.6569 | 0.0040 | |
| SRP219564 | ZNF43 | 7594 | RNAseq | 0.2372 | 0.6898 | |
| TCGA | ZNF43 | 7594 | RNAseq | -0.6017 | 0.0058 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZNF43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF43 | 7594 | 5 | 5 | 20 | |
| GSE20123 | ZNF43 | 7594 | 5 | 3 | 22 | |
| GSE43470 | ZNF43 | 7594 | 2 | 6 | 35 | |
| GSE46452 | ZNF43 | 7594 | 47 | 1 | 11 | |
| GSE47630 | ZNF43 | 7594 | 7 | 7 | 26 | |
| GSE54993 | ZNF43 | 7594 | 17 | 3 | 50 | |
| GSE54994 | ZNF43 | 7594 | 6 | 13 | 34 | |
| GSE60625 | ZNF43 | 7594 | 9 | 0 | 2 | |
| GSE74703 | ZNF43 | 7594 | 2 | 4 | 30 | |
| GSE74704 | ZNF43 | 7594 | 2 | 3 | 15 | |
| TCGA | ZNF43 | 7594 | 17 | 13 | 66 |
Total number of gains: 119; Total number of losses: 58; Total Number of normals: 311.
Somatic mutations of ZNF43:
Generating mutation plots.
Highly correlated genes for ZNF43:
Showing top 20/372 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF43 | ZNF85 | 0.756634 | 10 | 0 | 9 |
| ZNF43 | ZNF347 | 0.706133 | 5 | 0 | 4 |
| ZNF43 | ZNF675 | 0.704653 | 9 | 0 | 8 |
| ZNF43 | ZNF91 | 0.701218 | 11 | 0 | 11 |
| ZNF43 | ZNF682 | 0.690958 | 9 | 0 | 8 |
| ZNF43 | ZNF626 | 0.681256 | 5 | 0 | 4 |
| ZNF43 | METTL25 | 0.679109 | 3 | 0 | 3 |
| ZNF43 | CADM1 | 0.67395 | 5 | 0 | 5 |
| ZNF43 | ZNF253 | 0.672046 | 8 | 0 | 6 |
| ZNF43 | ZNF439 | 0.66865 | 6 | 0 | 6 |
| ZNF43 | ZNF708 | 0.667114 | 4 | 0 | 4 |
| ZNF43 | ZNF93 | 0.666535 | 10 | 0 | 7 |
| ZNF43 | ZNF738 | 0.664253 | 6 | 0 | 5 |
| ZNF43 | ZNF493 | 0.656396 | 9 | 0 | 7 |
| ZNF43 | ZNF844 | 0.655352 | 6 | 0 | 5 |
| ZNF43 | RNF125 | 0.65289 | 5 | 0 | 4 |
| ZNF43 | TRAPPC8 | 0.648076 | 7 | 0 | 6 |
| ZNF43 | KDM6A | 0.640361 | 4 | 0 | 4 |
| ZNF43 | ZFP28 | 0.639975 | 6 | 0 | 6 |
| ZNF43 | ZNF850 | 0.638367 | 3 | 0 | 3 |
For details and further investigation, click here
