| Full name: EI24 autophagy associated transmembrane protein | Alias Symbol: PIG8|TP53I8|EPG4 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 9538 | HGNC ID: HGNC:13276 | Ensembl Gene: ENSG00000149547 | OMIM ID: 605170 |
| Drug and gene relationship at DGIdb | |||
EI24 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04115 | p53 signaling pathway |
Expression of EI24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EI24 | 9538 | 216396_s_at | 0.2362 | 0.5263 | |
| GSE20347 | EI24 | 9538 | 208289_s_at | -0.4543 | 0.0028 | |
| GSE23400 | EI24 | 9538 | 216396_s_at | -0.0861 | 0.3194 | |
| GSE26886 | EI24 | 9538 | 216396_s_at | -0.6295 | 0.0095 | |
| GSE29001 | EI24 | 9538 | 216396_s_at | -0.2639 | 0.3216 | |
| GSE38129 | EI24 | 9538 | 208289_s_at | -0.2877 | 0.0124 | |
| GSE45670 | EI24 | 9538 | 216396_s_at | 0.0801 | 0.5886 | |
| GSE53622 | EI24 | 9538 | 126554 | -0.4680 | 0.0000 | |
| GSE53624 | EI24 | 9538 | 126554 | -0.2603 | 0.0000 | |
| GSE63941 | EI24 | 9538 | 208289_s_at | -0.8378 | 0.0080 | |
| GSE77861 | EI24 | 9538 | 208289_s_at | -0.1224 | 0.7192 | |
| GSE97050 | EI24 | 9538 | A_24_P4661 | 0.2395 | 0.3659 | |
| SRP007169 | EI24 | 9538 | RNAseq | -0.6751 | 0.1158 | |
| SRP008496 | EI24 | 9538 | RNAseq | -0.3728 | 0.0954 | |
| SRP064894 | EI24 | 9538 | RNAseq | -0.2693 | 0.1196 | |
| SRP133303 | EI24 | 9538 | RNAseq | -0.1999 | 0.0883 | |
| SRP159526 | EI24 | 9538 | RNAseq | -0.5137 | 0.0565 | |
| SRP193095 | EI24 | 9538 | RNAseq | -0.6467 | 0.0000 | |
| SRP219564 | EI24 | 9538 | RNAseq | -0.4553 | 0.0942 | |
| TCGA | EI24 | 9538 | RNAseq | 0.0114 | 0.8160 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EI24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EI24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EI24 | 9538 | 0 | 13 | 17 | |
| GSE20123 | EI24 | 9538 | 0 | 13 | 17 | |
| GSE43470 | EI24 | 9538 | 2 | 7 | 34 | |
| GSE46452 | EI24 | 9538 | 3 | 26 | 30 | |
| GSE47630 | EI24 | 9538 | 2 | 19 | 19 | |
| GSE54993 | EI24 | 9538 | 10 | 0 | 60 | |
| GSE54994 | EI24 | 9538 | 5 | 19 | 29 | |
| GSE60625 | EI24 | 9538 | 0 | 3 | 8 | |
| GSE74703 | EI24 | 9538 | 1 | 5 | 30 | |
| GSE74704 | EI24 | 9538 | 0 | 9 | 11 | |
| TCGA | EI24 | 9538 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of EI24:
Generating mutation plots.
Highly correlated genes for EI24:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EI24 | KCTD15 | 0.831981 | 3 | 0 | 3 |
| EI24 | TAP2 | 0.798402 | 3 | 0 | 3 |
| EI24 | MED23 | 0.792567 | 3 | 0 | 3 |
| EI24 | TRIM8 | 0.781386 | 3 | 0 | 3 |
| EI24 | SLC35B3 | 0.762361 | 4 | 0 | 4 |
| EI24 | ZNF92 | 0.761896 | 3 | 0 | 3 |
| EI24 | YIPF3 | 0.755083 | 3 | 0 | 3 |
| EI24 | SENP8 | 0.752662 | 3 | 0 | 3 |
| EI24 | ZNF578 | 0.748028 | 3 | 0 | 3 |
| EI24 | PROSER1 | 0.743822 | 4 | 0 | 3 |
| EI24 | TPM3 | 0.735817 | 3 | 0 | 3 |
| EI24 | ALG14 | 0.731241 | 3 | 0 | 3 |
| EI24 | TPD52L2 | 0.729317 | 3 | 0 | 3 |
| EI24 | ARHGAP31 | 0.727072 | 3 | 0 | 3 |
| EI24 | PDIK1L | 0.726089 | 3 | 0 | 3 |
| EI24 | C6orf136 | 0.717209 | 3 | 0 | 3 |
| EI24 | SCAMP3 | 0.714483 | 4 | 0 | 3 |
| EI24 | RFNG | 0.713419 | 4 | 0 | 3 |
| EI24 | NAA25 | 0.713126 | 3 | 0 | 3 |
| EI24 | ACSL5 | 0.708625 | 3 | 0 | 3 |
For details and further investigation, click here
