| Full name: SNF2 histone linker PHD RING helicase | Alias Symbol: FLJ90837|KIAA2023|bA545I5.2 | ||
| Type: protein-coding gene | Cytoband: 6q24.3 | ||
| Entrez ID: 257218 | HGNC ID: HGNC:19336 | Ensembl Gene: ENSG00000146414 | OMIM ID: 608048 |
| Drug and gene relationship at DGIdb | |||
Expression of SHPRH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHPRH | 257218 | 226366_at | -0.0984 | 0.8865 | |
| GSE26886 | SHPRH | 257218 | 226366_at | 0.6385 | 0.0176 | |
| GSE45670 | SHPRH | 257218 | 226366_at | -0.1476 | 0.3807 | |
| GSE53622 | SHPRH | 257218 | 78041 | 0.1251 | 0.0506 | |
| GSE53624 | SHPRH | 257218 | 78041 | 0.0654 | 0.3070 | |
| GSE63941 | SHPRH | 257218 | 226366_at | -0.5919 | 0.1770 | |
| GSE77861 | SHPRH | 257218 | 226366_at | 0.0336 | 0.9395 | |
| GSE97050 | SHPRH | 257218 | A_33_P3216083 | -0.7007 | 0.1476 | |
| SRP007169 | SHPRH | 257218 | RNAseq | 0.4269 | 0.2040 | |
| SRP008496 | SHPRH | 257218 | RNAseq | 0.7060 | 0.0014 | |
| SRP064894 | SHPRH | 257218 | RNAseq | -0.2561 | 0.5558 | |
| SRP133303 | SHPRH | 257218 | RNAseq | -0.1450 | 0.1588 | |
| SRP159526 | SHPRH | 257218 | RNAseq | -0.1931 | 0.5161 | |
| SRP193095 | SHPRH | 257218 | RNAseq | -0.1982 | 0.0531 | |
| SRP219564 | SHPRH | 257218 | RNAseq | -0.6901 | 0.2230 | |
| TCGA | SHPRH | 257218 | RNAseq | -0.1403 | 0.0120 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SHPRH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHPRH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHPRH | 257218 | 2 | 4 | 24 | |
| GSE20123 | SHPRH | 257218 | 2 | 3 | 25 | |
| GSE43470 | SHPRH | 257218 | 5 | 0 | 38 | |
| GSE46452 | SHPRH | 257218 | 3 | 11 | 45 | |
| GSE47630 | SHPRH | 257218 | 9 | 4 | 27 | |
| GSE54993 | SHPRH | 257218 | 3 | 2 | 65 | |
| GSE54994 | SHPRH | 257218 | 8 | 8 | 37 | |
| GSE60625 | SHPRH | 257218 | 0 | 1 | 10 | |
| GSE74703 | SHPRH | 257218 | 4 | 0 | 32 | |
| GSE74704 | SHPRH | 257218 | 0 | 1 | 19 | |
| TCGA | SHPRH | 257218 | 13 | 20 | 63 |
Total number of gains: 49; Total number of losses: 54; Total Number of normals: 385.
Somatic mutations of SHPRH:
Generating mutation plots.
Highly correlated genes for SHPRH:
Showing top 20/367 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHPRH | ZNF766 | 0.803501 | 3 | 0 | 3 |
| SHPRH | MSI2 | 0.764882 | 3 | 0 | 3 |
| SHPRH | SP1 | 0.758253 | 3 | 0 | 3 |
| SHPRH | CASC4 | 0.748554 | 3 | 0 | 3 |
| SHPRH | EIF2D | 0.739596 | 3 | 0 | 3 |
| SHPRH | ZNF3 | 0.739428 | 3 | 0 | 3 |
| SHPRH | IFT74 | 0.739194 | 4 | 0 | 4 |
| SHPRH | OTUD7B | 0.737262 | 3 | 0 | 3 |
| SHPRH | PUS7L | 0.735554 | 3 | 0 | 3 |
| SHPRH | NNT-AS1 | 0.732335 | 3 | 0 | 3 |
| SHPRH | ZNF566 | 0.732058 | 4 | 0 | 4 |
| SHPRH | ZNF257 | 0.731507 | 3 | 0 | 3 |
| SHPRH | SLC25A14 | 0.731047 | 3 | 0 | 3 |
| SHPRH | THAP9 | 0.723432 | 3 | 0 | 3 |
| SHPRH | C9orf78 | 0.722173 | 3 | 0 | 3 |
| SHPRH | GNPTAB | 0.721456 | 4 | 0 | 3 |
| SHPRH | GABPA | 0.719791 | 3 | 0 | 3 |
| SHPRH | PPARG | 0.718495 | 3 | 0 | 3 |
| SHPRH | ZNF383 | 0.717708 | 3 | 0 | 3 |
| SHPRH | ZSCAN12 | 0.717345 | 3 | 0 | 3 |
For details and further investigation, click here
