BOLA2

 

Full name: bolA family member 2 Alias Symbol: My016|BOLA2A
Type: protein-coding gene Cytoband: 16p11.2
Entrez ID: 552900 HGNC ID: HGNC:29488 Ensembl Gene: ENSG00000183336 OMIM ID: 613182
Drug and gene relationship at DGIdb

 

Expression of BOLA2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BOLA2 552900 241644_at 0.0667 0.7796
GSE26886 BOLA2 552900 241644_at -0.0042 0.9759
GSE45670 BOLA2 552900 231500_s_at 0.1642 0.3149
GSE63941 BOLA2 552900 231500_s_at 0.5509 0.1761
GSE77861 BOLA2 552900 241644_at 0.0245 0.9050
SRP064894 BOLA2 552900 RNAseq 0.2587 0.4821
SRP133303 BOLA2 552900 RNAseq -0.4952 0.0596
SRP159526 BOLA2 552900 RNAseq 0.2806 0.6071
SRP193095 BOLA2 552900 RNAseq -0.3067 0.2425
SRP219564 BOLA2 552900 RNAseq -0.6612 0.0113
TCGA BOLA2 552900 RNAseq 0.3279 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by BOLA2 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of BOLA2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BOLA2 552900 5 5 20
GSE20123 BOLA2 552900 5 4 21
GSE43470 BOLA2 552900 3 3 37
GSE46452 BOLA2 552900 38 1 20
GSE47630 BOLA2 552900 11 7 22
GSE54993 BOLA2 552900 3 5 62
GSE54994 BOLA2 552900 5 9 39
GSE60625 BOLA2 552900 4 0 7
GSE74703 BOLA2 552900 3 2 31
GSE74704 BOLA2 552900 3 2 15
TCGA BOLA2 552900 20 11 65

Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.  

 

Somatic mutations of BOLA2:

 

Generating mutation plots.

 

Highly correlated genes for BOLA2:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BOLA2GBX10.691842303
BOLA2MYOD10.599437303
BOLA2GNB20.598802303
BOLA2C16orf740.59244303
BOLA2C9orf430.568218303
BOLA2MRPS340.561862303
BOLA2NPRL30.557363303
BOLA2TBX200.550717303
BOLA2UBE2I0.541363303

For details and further investigation, click here