| Full name: ubiquitin conjugating enzyme E2 I | Alias Symbol: UBC9 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 7329 | HGNC ID: HGNC:12485 | Ensembl Gene: ENSG00000103275 | OMIM ID: 601661 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2I:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2I | 7329 | 213535_s_at | 0.5199 | 0.1256 | |
| GSE20347 | UBE2I | 7329 | 213535_s_at | 0.4134 | 0.0045 | |
| GSE23400 | UBE2I | 7329 | 213535_s_at | 0.5084 | 0.0000 | |
| GSE26886 | UBE2I | 7329 | 213535_s_at | 0.3348 | 0.0196 | |
| GSE29001 | UBE2I | 7329 | 213535_s_at | 0.4102 | 0.2778 | |
| GSE38129 | UBE2I | 7329 | 213535_s_at | 0.5959 | 0.0000 | |
| GSE45670 | UBE2I | 7329 | 213535_s_at | 0.3044 | 0.0042 | |
| GSE53622 | UBE2I | 7329 | 22968 | 0.2486 | 0.0000 | |
| GSE53624 | UBE2I | 7329 | 22968 | 0.4745 | 0.0000 | |
| GSE63941 | UBE2I | 7329 | 213535_s_at | 0.6080 | 0.0190 | |
| GSE77861 | UBE2I | 7329 | 213535_s_at | 0.3572 | 0.1185 | |
| GSE97050 | UBE2I | 7329 | A_33_P3292851 | -0.0621 | 0.7743 | |
| SRP007169 | UBE2I | 7329 | RNAseq | -0.1091 | 0.7368 | |
| SRP008496 | UBE2I | 7329 | RNAseq | -0.1672 | 0.4326 | |
| SRP064894 | UBE2I | 7329 | RNAseq | 0.1035 | 0.4893 | |
| SRP133303 | UBE2I | 7329 | RNAseq | 0.3836 | 0.0219 | |
| SRP159526 | UBE2I | 7329 | RNAseq | 0.1717 | 0.4748 | |
| SRP193095 | UBE2I | 7329 | RNAseq | 0.1269 | 0.2821 | |
| SRP219564 | UBE2I | 7329 | RNAseq | 0.4366 | 0.1236 | |
| TCGA | UBE2I | 7329 | RNAseq | 0.2177 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBE2I expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2I:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2I | 7329 | 5 | 5 | 20 | |
| GSE20123 | UBE2I | 7329 | 5 | 4 | 21 | |
| GSE43470 | UBE2I | 7329 | 4 | 7 | 32 | |
| GSE46452 | UBE2I | 7329 | 38 | 1 | 20 | |
| GSE47630 | UBE2I | 7329 | 13 | 6 | 21 | |
| GSE54993 | UBE2I | 7329 | 3 | 5 | 62 | |
| GSE54994 | UBE2I | 7329 | 5 | 9 | 39 | |
| GSE60625 | UBE2I | 7329 | 4 | 0 | 7 | |
| GSE74703 | UBE2I | 7329 | 4 | 5 | 27 | |
| GSE74704 | UBE2I | 7329 | 3 | 2 | 15 | |
| TCGA | UBE2I | 7329 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of UBE2I:
Generating mutation plots.
Highly correlated genes for UBE2I:
Showing top 20/322 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2I | CECR2 | 0.772116 | 3 | 0 | 3 |
| UBE2I | SNORA71A | 0.729332 | 3 | 0 | 3 |
| UBE2I | UBXN2B | 0.719535 | 3 | 0 | 3 |
| UBE2I | CDK12 | 0.709575 | 4 | 0 | 4 |
| UBE2I | TBC1D7 | 0.695558 | 4 | 0 | 3 |
| UBE2I | TUBB | 0.693899 | 9 | 0 | 8 |
| UBE2I | PRPF19 | 0.692946 | 7 | 0 | 7 |
| UBE2I | CXorf56 | 0.688707 | 6 | 0 | 6 |
| UBE2I | FEN1 | 0.687464 | 8 | 0 | 8 |
| UBE2I | LENG1 | 0.685767 | 3 | 0 | 3 |
| UBE2I | APTX | 0.685187 | 4 | 0 | 3 |
| UBE2I | ZFP69B | 0.681402 | 5 | 0 | 5 |
| UBE2I | C16orf91 | 0.675783 | 8 | 0 | 7 |
| UBE2I | RNASEH2A | 0.675477 | 10 | 0 | 8 |
| UBE2I | DCTPP1 | 0.674138 | 12 | 0 | 10 |
| UBE2I | TXNDC12 | 0.669401 | 5 | 0 | 4 |
| UBE2I | RANBP1 | 0.667304 | 10 | 0 | 8 |
| UBE2I | SEPHS2 | 0.664591 | 9 | 0 | 8 |
| UBE2I | MAP7D2 | 0.660269 | 4 | 0 | 4 |
| UBE2I | GINS2 | 0.658923 | 11 | 0 | 10 |
For details and further investigation, click here
