| Full name: carboxypeptidase N subunit 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 1369 | HGNC ID: HGNC:2312 | Ensembl Gene: ENSG00000120054 | OMIM ID: 603103 |
| Drug and gene relationship at DGIdb | |||
Expression of CPN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPN1 | 1369 | 206256_at | 0.1773 | 0.3937 | |
| GSE20347 | CPN1 | 1369 | 206256_at | -0.1280 | 0.1332 | |
| GSE23400 | CPN1 | 1369 | 206256_at | -0.2000 | 0.0000 | |
| GSE26886 | CPN1 | 1369 | 206256_at | 0.1499 | 0.2419 | |
| GSE29001 | CPN1 | 1369 | 206256_at | -0.0853 | 0.4847 | |
| GSE38129 | CPN1 | 1369 | 206256_at | -0.1698 | 0.0642 | |
| GSE45670 | CPN1 | 1369 | 206256_at | 0.0428 | 0.7297 | |
| GSE53622 | CPN1 | 1369 | 74913 | 0.1777 | 0.0175 | |
| GSE53624 | CPN1 | 1369 | 74913 | 0.2385 | 0.1701 | |
| GSE63941 | CPN1 | 1369 | 206256_at | 0.2232 | 0.2242 | |
| GSE77861 | CPN1 | 1369 | 206256_at | -0.1244 | 0.2132 | |
| GSE97050 | CPN1 | 1369 | A_23_P98147 | 0.0971 | 0.6348 | |
| TCGA | CPN1 | 1369 | RNAseq | 1.5138 | 0.2989 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CPN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPN1 | 1369 | 1 | 8 | 21 | |
| GSE20123 | CPN1 | 1369 | 1 | 7 | 22 | |
| GSE43470 | CPN1 | 1369 | 0 | 7 | 36 | |
| GSE46452 | CPN1 | 1369 | 0 | 11 | 48 | |
| GSE47630 | CPN1 | 1369 | 2 | 14 | 24 | |
| GSE54993 | CPN1 | 1369 | 8 | 0 | 62 | |
| GSE54994 | CPN1 | 1369 | 1 | 12 | 40 | |
| GSE60625 | CPN1 | 1369 | 0 | 0 | 11 | |
| GSE74703 | CPN1 | 1369 | 0 | 5 | 31 | |
| GSE74704 | CPN1 | 1369 | 0 | 4 | 16 | |
| TCGA | CPN1 | 1369 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of CPN1:
Generating mutation plots.
Highly correlated genes for CPN1:
Showing top 20/951 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPN1 | MAGEA8 | 0.782724 | 3 | 0 | 3 |
| CPN1 | AICDA | 0.761702 | 3 | 0 | 3 |
| CPN1 | FAM151A | 0.757704 | 3 | 0 | 3 |
| CPN1 | CCL27 | 0.745011 | 4 | 0 | 4 |
| CPN1 | SLC24A4 | 0.743597 | 3 | 0 | 3 |
| CPN1 | OR2H2 | 0.740347 | 5 | 0 | 5 |
| CPN1 | RENBP | 0.739465 | 3 | 0 | 3 |
| CPN1 | FNDC9 | 0.738014 | 4 | 0 | 3 |
| CPN1 | SLC6A3 | 0.732246 | 4 | 0 | 4 |
| CPN1 | FGF22 | 0.729337 | 4 | 0 | 4 |
| CPN1 | SLC9A7 | 0.727377 | 4 | 0 | 4 |
| CPN1 | AMELY | 0.723414 | 3 | 0 | 3 |
| CPN1 | GDF3 | 0.721127 | 4 | 0 | 4 |
| CPN1 | KIRREL2 | 0.717702 | 3 | 0 | 3 |
| CPN1 | DHRS7C | 0.71473 | 4 | 0 | 3 |
| CPN1 | RIN1 | 0.714504 | 3 | 0 | 3 |
| CPN1 | IQCF5-AS1 | 0.713071 | 3 | 0 | 3 |
| CPN1 | PIWIL2 | 0.712245 | 5 | 0 | 4 |
| CPN1 | FSTL4 | 0.710005 | 4 | 0 | 4 |
| CPN1 | CGA | 0.702945 | 4 | 0 | 3 |
For details and further investigation, click here
