| Full name: Ras and Rab interactor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 9610 | HGNC ID: HGNC:18749 | Ensembl Gene: ENSG00000174791 | OMIM ID: 605965 |
| Drug and gene relationship at DGIdb | |||
RIN1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04014 | Ras signaling pathway |
Expression of RIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIN1 | 9610 | 205211_s_at | 0.3476 | 0.5071 | |
| GSE20347 | RIN1 | 9610 | 205211_s_at | -0.0101 | 0.9395 | |
| GSE23400 | RIN1 | 9610 | 205211_s_at | 0.0321 | 0.5979 | |
| GSE26886 | RIN1 | 9610 | 205211_s_at | 0.7373 | 0.0003 | |
| GSE29001 | RIN1 | 9610 | 205211_s_at | -0.2565 | 0.4764 | |
| GSE38129 | RIN1 | 9610 | 205211_s_at | 0.0149 | 0.9266 | |
| GSE45670 | RIN1 | 9610 | 205211_s_at | 0.2432 | 0.0288 | |
| GSE53622 | RIN1 | 9610 | 26121 | -0.0179 | 0.9002 | |
| GSE53624 | RIN1 | 9610 | 26121 | -0.0257 | 0.7825 | |
| GSE63941 | RIN1 | 9610 | 205211_s_at | 0.2362 | 0.3802 | |
| GSE77861 | RIN1 | 9610 | 205211_s_at | 0.0926 | 0.7439 | |
| GSE97050 | RIN1 | 9610 | A_33_P3266010 | 0.4375 | 0.3186 | |
| SRP007169 | RIN1 | 9610 | RNAseq | -1.0727 | 0.0388 | |
| SRP008496 | RIN1 | 9610 | RNAseq | -0.6564 | 0.0871 | |
| SRP064894 | RIN1 | 9610 | RNAseq | -0.0411 | 0.8646 | |
| SRP133303 | RIN1 | 9610 | RNAseq | -0.2167 | 0.2962 | |
| SRP159526 | RIN1 | 9610 | RNAseq | -1.1195 | 0.0001 | |
| SRP193095 | RIN1 | 9610 | RNAseq | -0.0420 | 0.7925 | |
| SRP219564 | RIN1 | 9610 | RNAseq | -0.0837 | 0.8825 | |
| TCGA | RIN1 | 9610 | RNAseq | 0.3003 | 0.0070 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIN1 | 9610 | 9 | 4 | 17 | |
| GSE20123 | RIN1 | 9610 | 9 | 4 | 17 | |
| GSE43470 | RIN1 | 9610 | 6 | 1 | 36 | |
| GSE46452 | RIN1 | 9610 | 11 | 3 | 45 | |
| GSE47630 | RIN1 | 9610 | 8 | 5 | 27 | |
| GSE54993 | RIN1 | 9610 | 3 | 0 | 67 | |
| GSE54994 | RIN1 | 9610 | 8 | 5 | 40 | |
| GSE60625 | RIN1 | 9610 | 0 | 3 | 8 | |
| GSE74703 | RIN1 | 9610 | 4 | 0 | 32 | |
| GSE74704 | RIN1 | 9610 | 7 | 2 | 11 | |
| TCGA | RIN1 | 9610 | 25 | 6 | 65 |
Total number of gains: 90; Total number of losses: 33; Total Number of normals: 365.
Somatic mutations of RIN1:
Generating mutation plots.
Highly correlated genes for RIN1:
Showing top 20/505 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIN1 | JSRP1 | 0.826242 | 3 | 0 | 3 |
| RIN1 | REG3A | 0.811513 | 3 | 0 | 3 |
| RIN1 | IL17RE | 0.800383 | 3 | 0 | 3 |
| RIN1 | WDR90 | 0.800075 | 3 | 0 | 3 |
| RIN1 | SP8 | 0.782141 | 3 | 0 | 3 |
| RIN1 | ZNF341 | 0.771594 | 3 | 0 | 3 |
| RIN1 | HIVEP2 | 0.767063 | 3 | 0 | 3 |
| RIN1 | CNTROB | 0.766997 | 3 | 0 | 3 |
| RIN1 | KCP | 0.764197 | 3 | 0 | 3 |
| RIN1 | MAPK15 | 0.763863 | 3 | 0 | 3 |
| RIN1 | RUNX1-IT1 | 0.762756 | 3 | 0 | 3 |
| RIN1 | CHST13 | 0.759273 | 3 | 0 | 3 |
| RIN1 | SPATA2L | 0.756974 | 4 | 0 | 4 |
| RIN1 | MGAT5B | 0.752657 | 4 | 0 | 4 |
| RIN1 | SEZ6L2 | 0.74667 | 3 | 0 | 3 |
| RIN1 | ARMC5 | 0.745196 | 3 | 0 | 3 |
| RIN1 | XRCC2 | 0.742765 | 4 | 0 | 4 |
| RIN1 | ARID3A | 0.73957 | 4 | 0 | 4 |
| RIN1 | SSTR2 | 0.73777 | 3 | 0 | 3 |
| RIN1 | GPR32 | 0.731869 | 3 | 0 | 3 |
For details and further investigation, click here
