| Full name: solute carrier family 24 member 4 | Alias Symbol: NCKX4 | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 123041 | HGNC ID: HGNC:10978 | Ensembl Gene: ENSG00000140090 | OMIM ID: 609840 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC24A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC24A4 | 123041 | 1568922_at | 0.0651 | 0.8087 | |
| GSE26886 | SLC24A4 | 123041 | 1568922_at | -0.0309 | 0.8059 | |
| GSE45670 | SLC24A4 | 123041 | 1568922_at | 0.1088 | 0.2846 | |
| GSE53622 | SLC24A4 | 123041 | 39265 | 0.0352 | 0.6703 | |
| GSE53624 | SLC24A4 | 123041 | 39265 | 0.1527 | 0.0540 | |
| GSE63941 | SLC24A4 | 123041 | 1568922_at | 0.1173 | 0.4613 | |
| GSE77861 | SLC24A4 | 123041 | 1568922_at | -0.1624 | 0.0737 | |
| GSE97050 | SLC24A4 | 123041 | A_33_P3318148 | 0.0250 | 0.9128 | |
| SRP007169 | SLC24A4 | 123041 | RNAseq | 1.0255 | 0.2436 | |
| SRP064894 | SLC24A4 | 123041 | RNAseq | -0.0135 | 0.9651 | |
| SRP133303 | SLC24A4 | 123041 | RNAseq | -0.2101 | 0.1763 | |
| SRP159526 | SLC24A4 | 123041 | RNAseq | -0.0272 | 0.9465 | |
| SRP193095 | SLC24A4 | 123041 | RNAseq | 0.1436 | 0.3336 | |
| SRP219564 | SLC24A4 | 123041 | RNAseq | -0.0607 | 0.8671 | |
| TCGA | SLC24A4 | 123041 | RNAseq | -1.0979 | 0.0104 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC24A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC24A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC24A4 | 123041 | 8 | 5 | 17 | |
| GSE20123 | SLC24A4 | 123041 | 8 | 4 | 18 | |
| GSE43470 | SLC24A4 | 123041 | 7 | 3 | 33 | |
| GSE46452 | SLC24A4 | 123041 | 16 | 3 | 40 | |
| GSE47630 | SLC24A4 | 123041 | 11 | 8 | 21 | |
| GSE54993 | SLC24A4 | 123041 | 3 | 8 | 59 | |
| GSE54994 | SLC24A4 | 123041 | 20 | 4 | 29 | |
| GSE60625 | SLC24A4 | 123041 | 0 | 2 | 9 | |
| GSE74703 | SLC24A4 | 123041 | 6 | 3 | 27 | |
| GSE74704 | SLC24A4 | 123041 | 4 | 3 | 13 | |
| TCGA | SLC24A4 | 123041 | 30 | 20 | 46 |
Total number of gains: 113; Total number of losses: 63; Total Number of normals: 312.
Somatic mutations of SLC24A4:
Generating mutation plots.
Highly correlated genes for SLC24A4:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC24A4 | MIXL1 | 0.753794 | 3 | 0 | 3 |
| SLC24A4 | GRIN2C | 0.752921 | 3 | 0 | 3 |
| SLC24A4 | CPN1 | 0.743597 | 3 | 0 | 3 |
| SLC24A4 | DNAI1 | 0.742592 | 3 | 0 | 3 |
| SLC24A4 | TMEM239 | 0.736685 | 3 | 0 | 3 |
| SLC24A4 | NPPB | 0.734055 | 4 | 0 | 3 |
| SLC24A4 | ACTL6B | 0.732074 | 3 | 0 | 3 |
| SLC24A4 | TBX4 | 0.72804 | 3 | 0 | 3 |
| SLC24A4 | TP53TG5 | 0.726514 | 3 | 0 | 3 |
| SLC24A4 | FAM71E2 | 0.72201 | 3 | 0 | 3 |
| SLC24A4 | FAM71A | 0.715024 | 4 | 0 | 3 |
| SLC24A4 | TNNI2 | 0.704959 | 3 | 0 | 3 |
| SLC24A4 | ZNF341 | 0.703089 | 3 | 0 | 3 |
| SLC24A4 | CACNA1G-AS1 | 0.702477 | 3 | 0 | 3 |
| SLC24A4 | LIMD1 | 0.700132 | 3 | 0 | 3 |
| SLC24A4 | TH | 0.698953 | 3 | 0 | 3 |
| SLC24A4 | IGLON5 | 0.69832 | 3 | 0 | 3 |
| SLC24A4 | PGC | 0.696362 | 3 | 0 | 3 |
| SLC24A4 | ZNF197 | 0.688263 | 3 | 0 | 3 |
| SLC24A4 | OPRD1 | 0.685802 | 4 | 0 | 3 |
For details and further investigation, click here
