GDF3

 

Full name: growth differentiation factor 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 12p13.31
Entrez ID: 9573 HGNC ID: HGNC:4218 Ensembl Gene: ENSG00000184344 OMIM ID: 606522
Drug and gene relationship at DGIdb

 

Expression of GDF3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GDF3 9573 220053_at -0.0383 0.8643
GSE20347 GDF3 9573 220053_at -0.0428 0.5392
GSE23400 GDF3 9573 220053_at -0.1809 0.0000
GSE26886 GDF3 9573 220053_at -0.2040 0.1327
GSE29001 GDF3 9573 220053_at -0.2714 0.0773
GSE38129 GDF3 9573 220053_at -0.1166 0.0600
GSE45670 GDF3 9573 220053_at 0.0731 0.3557
GSE53622 GDF3 9573 107196 0.0880 0.5062
GSE53624 GDF3 9573 107196 0.0223 0.8305
GSE63941 GDF3 9573 220053_at 0.1922 0.1734
GSE77861 GDF3 9573 220053_at -0.0737 0.5482
TCGA GDF3 9573 RNAseq 1.9420 0.0417

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by GDF3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GDF3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GDF3 9573 6 3 21
GSE20123 GDF3 9573 6 3 21
GSE43470 GDF3 9573 7 3 33
GSE46452 GDF3 9573 10 1 48
GSE47630 GDF3 9573 12 2 26
GSE54993 GDF3 9573 1 10 59
GSE54994 GDF3 9573 9 5 39
GSE60625 GDF3 9573 0 1 10
GSE74703 GDF3 9573 7 2 27
GSE74704 GDF3 9573 4 2 14
TCGA GDF3 9573 40 6 50

Total number of gains: 102; Total number of losses: 38; Total Number of normals: 348.  


 

Somatic mutations of GDF3:

 

Generating mutation plots.

 

Highly correlated genes for GDF3:

 

Showing top 20/875 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GDF3SLC4A40.750518404
GDF3RHAG0.739731303
GDF3CPN10.721127404
GDF3CNR20.709318505
GDF3TBX50.706248404
GDF3CGA0.706011404
GDF3KCNJ100.688682606
GDF3CTRC0.688647303
GDF3ADM20.687468505
GDF3CBL0.684842404
GDF3HAND10.683779505
GDF3PRB10.679829606
GDF3EDA2R0.672511504
GDF3NOX50.67184504
GDF3RSPH6A0.671431606
GDF3ART10.671428605
GDF3PTPRO0.670939303
GDF3NCR10.670124504
GDF3ADRB30.668286303
GDF3TCTN20.667381303

For details and further investigation, click here