| Full name: piwi like RNA-mediated gene silencing 2 | Alias Symbol: HILI|FLJ10351|Mili|CT80 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 55124 | HGNC ID: HGNC:17644 | Ensembl Gene: ENSG00000197181 | OMIM ID: 610312 |
| Drug and gene relationship at DGIdb | |||
Expression of PIWIL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIWIL2 | 55124 | 217421_at | -0.2598 | 0.1977 | |
| GSE20347 | PIWIL2 | 55124 | 217421_at | -0.3056 | 0.0163 | |
| GSE23400 | PIWIL2 | 55124 | 217421_at | -0.3280 | 0.0000 | |
| GSE26886 | PIWIL2 | 55124 | 220686_s_at | 0.2978 | 0.1424 | |
| GSE29001 | PIWIL2 | 55124 | 217421_at | -0.3057 | 0.0607 | |
| GSE38129 | PIWIL2 | 55124 | 217421_at | -0.4142 | 0.0001 | |
| GSE45670 | PIWIL2 | 55124 | 220686_s_at | 0.0681 | 0.7780 | |
| GSE53622 | PIWIL2 | 55124 | 40853 | 0.2278 | 0.0618 | |
| GSE53624 | PIWIL2 | 55124 | 40853 | 0.1754 | 0.0745 | |
| GSE63941 | PIWIL2 | 55124 | 217421_at | 0.0596 | 0.8158 | |
| GSE77861 | PIWIL2 | 55124 | 217421_at | -0.2566 | 0.0383 | |
| GSE97050 | PIWIL2 | 55124 | A_23_P253074 | 0.4860 | 0.3826 | |
| SRP133303 | PIWIL2 | 55124 | RNAseq | 1.1987 | 0.0071 | |
| SRP219564 | PIWIL2 | 55124 | RNAseq | 0.1586 | 0.6927 | |
| TCGA | PIWIL2 | 55124 | RNAseq | -0.4468 | 0.5357 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PIWIL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIWIL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIWIL2 | 55124 | 4 | 10 | 16 | |
| GSE20123 | PIWIL2 | 55124 | 4 | 10 | 16 | |
| GSE43470 | PIWIL2 | 55124 | 4 | 9 | 30 | |
| GSE46452 | PIWIL2 | 55124 | 13 | 13 | 33 | |
| GSE47630 | PIWIL2 | 55124 | 10 | 8 | 22 | |
| GSE54993 | PIWIL2 | 55124 | 2 | 14 | 54 | |
| GSE54994 | PIWIL2 | 55124 | 9 | 17 | 27 | |
| GSE60625 | PIWIL2 | 55124 | 3 | 0 | 8 | |
| GSE74703 | PIWIL2 | 55124 | 4 | 7 | 25 | |
| GSE74704 | PIWIL2 | 55124 | 3 | 7 | 10 | |
| TCGA | PIWIL2 | 55124 | 14 | 43 | 39 |
Total number of gains: 70; Total number of losses: 138; Total Number of normals: 280.
Somatic mutations of PIWIL2:
Generating mutation plots.
Highly correlated genes for PIWIL2:
Showing top 20/949 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIWIL2 | ART1 | 0.762694 | 4 | 0 | 4 |
| PIWIL2 | LHX9 | 0.743537 | 3 | 0 | 3 |
| PIWIL2 | SCGB1A1 | 0.740228 | 3 | 0 | 3 |
| PIWIL2 | OR10H3 | 0.729262 | 4 | 0 | 4 |
| PIWIL2 | ONECUT3 | 0.727349 | 3 | 0 | 3 |
| PIWIL2 | KRT32 | 0.724246 | 7 | 0 | 7 |
| PIWIL2 | SLC22A14 | 0.717678 | 7 | 0 | 7 |
| PIWIL2 | IGFL1 | 0.716508 | 3 | 0 | 3 |
| PIWIL2 | CPN1 | 0.712245 | 5 | 0 | 4 |
| PIWIL2 | CYP3A43 | 0.712105 | 6 | 0 | 6 |
| PIWIL2 | GNRHR | 0.711499 | 5 | 0 | 5 |
| PIWIL2 | GGT6 | 0.70901 | 3 | 0 | 3 |
| PIWIL2 | HTR4 | 0.708117 | 5 | 0 | 5 |
| PIWIL2 | KIR2DS2 | 0.707289 | 4 | 0 | 4 |
| PIWIL2 | RNF17 | 0.702535 | 5 | 0 | 4 |
| PIWIL2 | KRT2 | 0.701976 | 6 | 0 | 6 |
| PIWIL2 | MATN1 | 0.700676 | 5 | 0 | 4 |
| PIWIL2 | FAXDC2 | 0.70018 | 5 | 0 | 5 |
| PIWIL2 | PAX3 | 0.699104 | 6 | 0 | 5 |
| PIWIL2 | IFNA21 | 0.696211 | 5 | 0 | 5 |
For details and further investigation, click here
