| Full name: carboxypeptidase N subunit 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 1370 | HGNC ID: HGNC:2313 | Ensembl Gene: ENSG00000178772 | OMIM ID: 603104 |
| Drug and gene relationship at DGIdb | |||
Expression of CPN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPN2 | 1370 | 216223_at | -0.0645 | 0.8191 | |
| GSE20347 | CPN2 | 1370 | 216223_at | 0.1216 | 0.0588 | |
| GSE23400 | CPN2 | 1370 | 216223_at | -0.0250 | 0.5710 | |
| GSE26886 | CPN2 | 1370 | 216223_at | -0.0789 | 0.5836 | |
| GSE29001 | CPN2 | 1370 | 216223_at | -0.0818 | 0.5187 | |
| GSE38129 | CPN2 | 1370 | 216223_at | 0.0341 | 0.5720 | |
| GSE45670 | CPN2 | 1370 | 216223_at | 0.1331 | 0.0564 | |
| GSE53622 | CPN2 | 1370 | 96646 | 0.7192 | 0.0000 | |
| GSE53624 | CPN2 | 1370 | 96646 | 0.2029 | 0.0935 | |
| GSE63941 | CPN2 | 1370 | 216223_at | 0.1301 | 0.2588 | |
| GSE77861 | CPN2 | 1370 | 216223_at | 0.0870 | 0.4222 | |
| SRP133303 | CPN2 | 1370 | RNAseq | 0.1541 | 0.3436 | |
| SRP159526 | CPN2 | 1370 | RNAseq | 0.6125 | 0.1433 | |
| SRP193095 | CPN2 | 1370 | RNAseq | 0.0519 | 0.7569 | |
| SRP219564 | CPN2 | 1370 | RNAseq | -0.0850 | 0.8877 | |
| TCGA | CPN2 | 1370 | RNAseq | -0.6888 | 0.2407 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CPN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPN2 | 1370 | 22 | 0 | 8 | |
| GSE20123 | CPN2 | 1370 | 22 | 0 | 8 | |
| GSE43470 | CPN2 | 1370 | 24 | 0 | 19 | |
| GSE46452 | CPN2 | 1370 | 19 | 1 | 39 | |
| GSE47630 | CPN2 | 1370 | 27 | 2 | 11 | |
| GSE54993 | CPN2 | 1370 | 1 | 21 | 48 | |
| GSE54994 | CPN2 | 1370 | 41 | 0 | 12 | |
| GSE60625 | CPN2 | 1370 | 0 | 6 | 5 | |
| GSE74703 | CPN2 | 1370 | 20 | 0 | 16 | |
| GSE74704 | CPN2 | 1370 | 14 | 0 | 6 | |
| TCGA | CPN2 | 1370 | 77 | 0 | 19 |
Total number of gains: 267; Total number of losses: 30; Total Number of normals: 191.
Somatic mutations of CPN2:
Generating mutation plots.
Highly correlated genes for CPN2:
Showing top 20/266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPN2 | VWA3A | 0.689201 | 3 | 0 | 3 |
| CPN2 | LINC00520 | 0.678071 | 3 | 0 | 3 |
| CPN2 | ZNF236 | 0.668857 | 4 | 0 | 4 |
| CPN2 | IFNA5 | 0.665751 | 4 | 0 | 4 |
| CPN2 | SCGN | 0.657439 | 3 | 0 | 3 |
| CPN2 | OR3A1 | 0.655746 | 3 | 0 | 3 |
| CPN2 | ZNF286A | 0.650511 | 4 | 0 | 4 |
| CPN2 | SLC25A31 | 0.649763 | 3 | 0 | 3 |
| CPN2 | ABCD2 | 0.648041 | 3 | 0 | 3 |
| CPN2 | GPD1 | 0.635498 | 4 | 0 | 4 |
| CPN2 | DLG5-AS1 | 0.632023 | 3 | 0 | 3 |
| CPN2 | OPRM1 | 0.630832 | 6 | 0 | 5 |
| CPN2 | BMP15 | 0.628776 | 5 | 0 | 4 |
| CPN2 | LINC01115 | 0.628578 | 3 | 0 | 3 |
| CPN2 | NNAT | 0.628014 | 4 | 0 | 4 |
| CPN2 | GRPR | 0.626039 | 4 | 0 | 3 |
| CPN2 | GPR22 | 0.6157 | 4 | 0 | 3 |
| CPN2 | HNF1B | 0.61546 | 6 | 0 | 4 |
| CPN2 | OR5I1 | 0.608623 | 3 | 0 | 3 |
| CPN2 | KRTAP4-4 | 0.606113 | 3 | 0 | 3 |
For details and further investigation, click here
