| Full name: ATP binding cassette subfamily D member 2 | Alias Symbol: ALDR|ALDRP | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 225 | HGNC ID: HGNC:66 | Ensembl Gene: ENSG00000173208 | OMIM ID: 601081 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCD2 | 225 | 207583_at | -0.1180 | 0.5640 | |
| GSE20347 | ABCD2 | 225 | 207583_at | 0.0291 | 0.6441 | |
| GSE23400 | ABCD2 | 225 | 207583_at | -0.0127 | 0.5262 | |
| GSE26886 | ABCD2 | 225 | 207583_at | 0.0508 | 0.5632 | |
| GSE29001 | ABCD2 | 225 | 207583_at | -0.1026 | 0.3758 | |
| GSE38129 | ABCD2 | 225 | 207583_at | -0.0248 | 0.6212 | |
| GSE45670 | ABCD2 | 225 | 207583_at | 0.0123 | 0.8833 | |
| GSE53622 | ABCD2 | 225 | 103138 | -1.2165 | 0.0000 | |
| GSE53624 | ABCD2 | 225 | 103138 | -0.4569 | 0.0036 | |
| GSE63941 | ABCD2 | 225 | 207583_at | 0.0645 | 0.6064 | |
| GSE77861 | ABCD2 | 225 | 207583_at | -0.0208 | 0.7739 | |
| GSE97050 | ABCD2 | 225 | A_23_P388124 | -0.3606 | 0.2874 | |
| SRP133303 | ABCD2 | 225 | RNAseq | -0.4594 | 0.2550 | |
| SRP193095 | ABCD2 | 225 | RNAseq | -0.5007 | 0.1248 | |
| TCGA | ABCD2 | 225 | RNAseq | -0.8633 | 0.0449 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ABCD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCD2 | 225 | 6 | 1 | 23 | |
| GSE20123 | ABCD2 | 225 | 6 | 1 | 23 | |
| GSE43470 | ABCD2 | 225 | 5 | 3 | 35 | |
| GSE46452 | ABCD2 | 225 | 8 | 1 | 50 | |
| GSE47630 | ABCD2 | 225 | 11 | 2 | 27 | |
| GSE54993 | ABCD2 | 225 | 1 | 8 | 61 | |
| GSE54994 | ABCD2 | 225 | 7 | 1 | 45 | |
| GSE60625 | ABCD2 | 225 | 0 | 0 | 11 | |
| GSE74703 | ABCD2 | 225 | 4 | 2 | 30 | |
| GSE74704 | ABCD2 | 225 | 3 | 1 | 16 | |
| TCGA | ABCD2 | 225 | 18 | 13 | 65 |
Total number of gains: 69; Total number of losses: 33; Total Number of normals: 386.
Somatic mutations of ABCD2:
Generating mutation plots.
Highly correlated genes for ABCD2:
Showing top 20/720 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCD2 | GIMAP5 | 0.801653 | 3 | 0 | 3 |
| ABCD2 | ARHGAP15 | 0.784598 | 3 | 0 | 3 |
| ABCD2 | AP2A2 | 0.774672 | 3 | 0 | 3 |
| ABCD2 | RCSD1 | 0.774274 | 4 | 0 | 4 |
| ABCD2 | C7 | 0.757733 | 3 | 0 | 3 |
| ABCD2 | P2RY12 | 0.748623 | 4 | 0 | 4 |
| ABCD2 | ARHGEF6 | 0.748086 | 4 | 0 | 4 |
| ABCD2 | TNFSF12 | 0.74279 | 3 | 0 | 3 |
| ABCD2 | PPM1K | 0.737576 | 3 | 0 | 3 |
| ABCD2 | GAB3 | 0.734355 | 4 | 0 | 4 |
| ABCD2 | ADCY9 | 0.725412 | 3 | 0 | 3 |
| ABCD2 | DOCK8 | 0.724045 | 4 | 0 | 4 |
| ABCD2 | TCF21 | 0.723653 | 4 | 0 | 4 |
| ABCD2 | GNG2 | 0.720764 | 3 | 0 | 3 |
| ABCD2 | OGN | 0.717349 | 4 | 0 | 4 |
| ABCD2 | EZH1 | 0.713807 | 3 | 0 | 3 |
| ABCD2 | RERGL | 0.71318 | 4 | 0 | 4 |
| ABCD2 | RHOU | 0.712219 | 4 | 0 | 3 |
| ABCD2 | PODN | 0.71136 | 5 | 0 | 5 |
| ABCD2 | ADH1C | 0.710071 | 4 | 0 | 3 |
For details and further investigation, click here
