| Full name: glycerol-3-phosphate dehydrogenase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 2819 | HGNC ID: HGNC:4455 | Ensembl Gene: ENSG00000167588 | OMIM ID: 138420 |
| Drug and gene relationship at DGIdb | |||
Expression of GPD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPD1 | 2819 | 213706_at | -0.0271 | 0.9612 | |
| GSE20347 | GPD1 | 2819 | 213706_at | 0.0543 | 0.5756 | |
| GSE23400 | GPD1 | 2819 | 213706_at | -0.1301 | 0.0014 | |
| GSE26886 | GPD1 | 2819 | 213706_at | 0.0224 | 0.8600 | |
| GSE29001 | GPD1 | 2819 | 213706_at | -0.1164 | 0.4745 | |
| GSE38129 | GPD1 | 2819 | 213706_at | -0.3415 | 0.1054 | |
| GSE45670 | GPD1 | 2819 | 1563034_at | -0.1002 | 0.3664 | |
| GSE53622 | GPD1 | 2819 | 43396 | -0.3375 | 0.0001 | |
| GSE53624 | GPD1 | 2819 | 43396 | -0.7444 | 0.0000 | |
| GSE63941 | GPD1 | 2819 | 213706_at | 0.2301 | 0.0995 | |
| GSE77861 | GPD1 | 2819 | 213706_at | -0.0882 | 0.4543 | |
| GSE97050 | GPD1 | 2819 | A_23_P204736 | 0.0428 | 0.8494 | |
| SRP133303 | GPD1 | 2819 | RNAseq | -1.3754 | 0.0000 | |
| SRP159526 | GPD1 | 2819 | RNAseq | -1.4518 | 0.0040 | |
| TCGA | GPD1 | 2819 | RNAseq | -1.8497 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by GPD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPD1 | 2819 | 8 | 1 | 21 | |
| GSE20123 | GPD1 | 2819 | 8 | 1 | 21 | |
| GSE43470 | GPD1 | 2819 | 3 | 0 | 40 | |
| GSE46452 | GPD1 | 2819 | 8 | 1 | 50 | |
| GSE47630 | GPD1 | 2819 | 11 | 2 | 27 | |
| GSE54993 | GPD1 | 2819 | 0 | 5 | 65 | |
| GSE54994 | GPD1 | 2819 | 4 | 1 | 48 | |
| GSE60625 | GPD1 | 2819 | 0 | 0 | 11 | |
| GSE74703 | GPD1 | 2819 | 3 | 0 | 33 | |
| GSE74704 | GPD1 | 2819 | 5 | 1 | 14 | |
| TCGA | GPD1 | 2819 | 15 | 11 | 70 |
Total number of gains: 65; Total number of losses: 23; Total Number of normals: 400.
Somatic mutations of GPD1:
Generating mutation plots.
Highly correlated genes for GPD1:
Showing top 20/923 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPD1 | POU4F3 | 0.745934 | 3 | 0 | 3 |
| GPD1 | PTGDR2 | 0.745639 | 3 | 0 | 3 |
| GPD1 | SEMA3B | 0.737914 | 3 | 0 | 3 |
| GPD1 | ASRGL1 | 0.734017 | 3 | 0 | 3 |
| GPD1 | ABCC6 | 0.733757 | 3 | 0 | 3 |
| GPD1 | PKLR | 0.73361 | 4 | 0 | 3 |
| GPD1 | CYP11B1 | 0.732635 | 5 | 0 | 5 |
| GPD1 | GRIN1 | 0.732595 | 4 | 0 | 4 |
| GPD1 | NCAN | 0.731983 | 4 | 0 | 4 |
| GPD1 | TRAF3IP2-AS1 | 0.728486 | 3 | 0 | 3 |
| GPD1 | BARHL2 | 0.726003 | 3 | 0 | 3 |
| GPD1 | F2 | 0.725278 | 4 | 0 | 4 |
| GPD1 | DNAJB8 | 0.724795 | 3 | 0 | 3 |
| GPD1 | GRM6 | 0.717825 | 4 | 0 | 4 |
| GPD1 | SLC6A3 | 0.717138 | 4 | 0 | 4 |
| GPD1 | PRAMEF12 | 0.7164 | 5 | 0 | 4 |
| GPD1 | KSR1 | 0.71529 | 4 | 0 | 3 |
| GPD1 | FUT7 | 0.712638 | 3 | 0 | 3 |
| GPD1 | IRS4 | 0.71262 | 3 | 0 | 3 |
| GPD1 | GPSM1 | 0.711759 | 4 | 0 | 4 |
For details and further investigation, click here
