| Full name: interferon alpha 5 | Alias Symbol: IFN-alphaG | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 3442 | HGNC ID: HGNC:5426 | Ensembl Gene: ENSG00000147873 | OMIM ID: 147565 |
| Drug and gene relationship at DGIdb | |||
IFNA5 involved pathways:
Expression of IFNA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNA5 | 3442 | 214569_at | -0.0782 | 0.6817 | |
| GSE20347 | IFNA5 | 3442 | 214569_at | -0.0621 | 0.2375 | |
| GSE23400 | IFNA5 | 3442 | 214569_at | -0.0784 | 0.0278 | |
| GSE26886 | IFNA5 | 3442 | 214569_at | -0.0964 | 0.2509 | |
| GSE29001 | IFNA5 | 3442 | 214569_at | -0.1807 | 0.3688 | |
| GSE38129 | IFNA5 | 3442 | 214569_at | -0.0701 | 0.1128 | |
| GSE45670 | IFNA5 | 3442 | 214569_at | 0.0725 | 0.4871 | |
| GSE63941 | IFNA5 | 3442 | 214569_at | -0.0096 | 0.9294 | |
| GSE77861 | IFNA5 | 3442 | 214569_at | 0.0600 | 0.4096 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNA5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IFNA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNA5 | 3442 | 2 | 17 | 11 | |
| GSE20123 | IFNA5 | 3442 | 2 | 17 | 11 | |
| GSE43470 | IFNA5 | 3442 | 4 | 13 | 26 | |
| GSE46452 | IFNA5 | 3442 | 2 | 23 | 34 | |
| GSE47630 | IFNA5 | 3442 | 3 | 27 | 10 | |
| GSE54993 | IFNA5 | 3442 | 7 | 2 | 61 | |
| GSE54994 | IFNA5 | 3442 | 8 | 16 | 29 | |
| GSE60625 | IFNA5 | 3442 | 3 | 0 | 8 | |
| GSE74703 | IFNA5 | 3442 | 4 | 10 | 22 | |
| GSE74704 | IFNA5 | 3442 | 0 | 13 | 7 | |
| TCGA | IFNA5 | 3442 | 11 | 53 | 32 |
Total number of gains: 46; Total number of losses: 191; Total Number of normals: 251.
Somatic mutations of IFNA5:
Generating mutation plots.
Highly correlated genes for IFNA5:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNA5 | GFM1 | 0.755042 | 3 | 0 | 3 |
| IFNA5 | CBLN1 | 0.739819 | 3 | 0 | 3 |
| IFNA5 | ATP6V1G2 | 0.739633 | 3 | 0 | 3 |
| IFNA5 | TEK | 0.734684 | 3 | 0 | 3 |
| IFNA5 | CADPS | 0.730594 | 4 | 0 | 4 |
| IFNA5 | PREX2 | 0.727005 | 3 | 0 | 3 |
| IFNA5 | MAPK4 | 0.723338 | 3 | 0 | 3 |
| IFNA5 | KIR2DS5 | 0.721836 | 3 | 0 | 3 |
| IFNA5 | STXBP6 | 0.718845 | 3 | 0 | 3 |
| IFNA5 | C6 | 0.717824 | 3 | 0 | 3 |
| IFNA5 | SLC17A7 | 0.714288 | 3 | 0 | 3 |
| IFNA5 | SLC6A5 | 0.713741 | 3 | 0 | 3 |
| IFNA5 | LUZP4 | 0.712054 | 3 | 0 | 3 |
| IFNA5 | CRHBP | 0.70496 | 3 | 0 | 3 |
| IFNA5 | ULK4 | 0.69521 | 3 | 0 | 3 |
| IFNA5 | GNG3 | 0.692569 | 3 | 0 | 3 |
| IFNA5 | SLC13A3 | 0.692345 | 4 | 0 | 3 |
| IFNA5 | EBF2 | 0.690985 | 3 | 0 | 3 |
| IFNA5 | FLRT1 | 0.688312 | 3 | 0 | 3 |
| IFNA5 | PRAMEF12 | 0.687353 | 4 | 0 | 3 |
For details and further investigation, click here
