| Full name: secretagogin, EF-hand calcium binding protein | Alias Symbol: SECRET|DJ501N12.8|SEGN|CALBL | ||
| Type: protein-coding gene | Cytoband: 6p22.2 | ||
| Entrez ID: 10590 | HGNC ID: HGNC:16941 | Ensembl Gene: ENSG00000079689 | OMIM ID: 609202 |
| Drug and gene relationship at DGIdb | |||
Expression of SCGN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCGN | 10590 | 205697_at | -0.0236 | 0.9714 | |
| GSE20347 | SCGN | 10590 | 205697_at | 0.0851 | 0.3965 | |
| GSE23400 | SCGN | 10590 | 205697_at | -0.1588 | 0.0003 | |
| GSE26886 | SCGN | 10590 | 205697_at | 0.1018 | 0.3170 | |
| GSE29001 | SCGN | 10590 | 205697_at | -0.0041 | 0.9829 | |
| GSE38129 | SCGN | 10590 | 205697_at | -0.0427 | 0.8506 | |
| GSE45670 | SCGN | 10590 | 205697_at | -0.0610 | 0.4187 | |
| GSE53622 | SCGN | 10590 | 116005 | 0.1828 | 0.1111 | |
| GSE53624 | SCGN | 10590 | 116005 | 0.0567 | 0.6404 | |
| GSE63941 | SCGN | 10590 | 205697_at | -0.3496 | 0.0504 | |
| GSE77861 | SCGN | 10590 | 205697_at | 0.0058 | 0.9679 | |
| GSE97050 | SCGN | 10590 | A_23_P251412 | -0.0122 | 0.9611 | |
| TCGA | SCGN | 10590 | RNAseq | -6.2180 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SCGN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCGN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCGN | 10590 | 4 | 2 | 24 | |
| GSE20123 | SCGN | 10590 | 4 | 2 | 24 | |
| GSE43470 | SCGN | 10590 | 5 | 0 | 38 | |
| GSE46452 | SCGN | 10590 | 1 | 9 | 49 | |
| GSE47630 | SCGN | 10590 | 8 | 5 | 27 | |
| GSE54993 | SCGN | 10590 | 1 | 1 | 68 | |
| GSE54994 | SCGN | 10590 | 10 | 4 | 39 | |
| GSE60625 | SCGN | 10590 | 0 | 1 | 10 | |
| GSE74703 | SCGN | 10590 | 5 | 0 | 31 | |
| GSE74704 | SCGN | 10590 | 1 | 1 | 18 | |
| TCGA | SCGN | 10590 | 15 | 21 | 60 |
Total number of gains: 54; Total number of losses: 46; Total Number of normals: 388.
Somatic mutations of SCGN:
Generating mutation plots.
Highly correlated genes for SCGN:
Showing top 20/802 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCGN | KLHL35 | 0.818986 | 3 | 0 | 3 |
| SCGN | OR2H2 | 0.804617 | 4 | 0 | 4 |
| SCGN | TMEM229A | 0.801669 | 3 | 0 | 3 |
| SCGN | SPTA1 | 0.79582 | 3 | 0 | 3 |
| SCGN | NXNL1 | 0.793878 | 3 | 0 | 3 |
| SCGN | CLCNKA | 0.783403 | 3 | 0 | 3 |
| SCGN | MYBPH | 0.780401 | 4 | 0 | 4 |
| SCGN | TSKS | 0.777419 | 4 | 0 | 3 |
| SCGN | ANO7 | 0.77732 | 4 | 0 | 4 |
| SCGN | SLC7A14 | 0.77585 | 3 | 0 | 3 |
| SCGN | CALCR | 0.771039 | 4 | 0 | 4 |
| SCGN | MAGEA8 | 0.760846 | 3 | 0 | 3 |
| SCGN | HAPLN1 | 0.758267 | 3 | 0 | 3 |
| SCGN | GRIN1 | 0.748772 | 5 | 0 | 4 |
| SCGN | TNXB | 0.747576 | 3 | 0 | 3 |
| SCGN | KIR3DL3 | 0.742026 | 4 | 0 | 4 |
| SCGN | SLC9A7 | 0.731293 | 3 | 0 | 3 |
| SCGN | ZNF81 | 0.730676 | 3 | 0 | 3 |
| SCGN | SLC12A3 | 0.729888 | 5 | 0 | 5 |
| SCGN | USP49 | 0.729589 | 4 | 0 | 4 |
For details and further investigation, click here
