| Full name: defensin beta 132 | Alias Symbol: RP5-1103G7.6|DEFB32 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 400830 | HGNC ID: HGNC:33806 | Ensembl Gene: ENSG00000186458 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DEFB132:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEFB132 | 400830 | 243311_at | -0.0687 | 0.7213 | |
| GSE26886 | DEFB132 | 400830 | 243311_at | 0.0699 | 0.5018 | |
| GSE45670 | DEFB132 | 400830 | 243311_at | 0.0641 | 0.2475 | |
| GSE53622 | DEFB132 | 400830 | 40333 | 0.0961 | 0.5245 | |
| GSE53624 | DEFB132 | 400830 | 40333 | -0.0942 | 0.5168 | |
| GSE63941 | DEFB132 | 400830 | 243311_at | 0.1109 | 0.4022 | |
| GSE77861 | DEFB132 | 400830 | 243311_at | -0.0290 | 0.7839 | |
| GSE97050 | DEFB132 | 400830 | A_33_P3316475 | -0.0405 | 0.8869 | |
| TCGA | DEFB132 | 400830 | RNAseq | -2.2163 | 0.3034 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DEFB132 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DEFB132:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEFB132 | 400830 | 12 | 4 | 14 | |
| GSE20123 | DEFB132 | 400830 | 13 | 4 | 13 | |
| GSE43470 | DEFB132 | 400830 | 11 | 1 | 31 | |
| GSE46452 | DEFB132 | 400830 | 26 | 1 | 32 | |
| GSE47630 | DEFB132 | 400830 | 19 | 4 | 17 | |
| GSE54993 | DEFB132 | 400830 | 2 | 15 | 53 | |
| GSE54994 | DEFB132 | 400830 | 24 | 2 | 27 | |
| GSE60625 | DEFB132 | 400830 | 0 | 0 | 11 | |
| GSE74703 | DEFB132 | 400830 | 10 | 1 | 25 | |
| GSE74704 | DEFB132 | 400830 | 8 | 2 | 10 | |
| TCGA | DEFB132 | 400830 | 41 | 11 | 44 |
Total number of gains: 166; Total number of losses: 45; Total Number of normals: 277.
Somatic mutations of DEFB132:
Generating mutation plots.
Highly correlated genes for DEFB132:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEFB132 | OR2AT4 | 0.814368 | 3 | 0 | 3 |
| DEFB132 | OR7G1 | 0.803288 | 3 | 0 | 3 |
| DEFB132 | KIR3DL2 | 0.80013 | 3 | 0 | 3 |
| DEFB132 | TP53AIP1 | 0.794103 | 3 | 0 | 3 |
| DEFB132 | KRTAP19-2 | 0.792598 | 3 | 0 | 3 |
| DEFB132 | ZNF878 | 0.786319 | 3 | 0 | 3 |
| DEFB132 | ZNF676 | 0.784179 | 3 | 0 | 3 |
| DEFB132 | ZNF225 | 0.781056 | 3 | 0 | 3 |
| DEFB132 | ZNF10 | 0.778935 | 3 | 0 | 3 |
| DEFB132 | OR2T33 | 0.75697 | 3 | 0 | 3 |
| DEFB132 | ZNF595 | 0.754471 | 3 | 0 | 3 |
| DEFB132 | DERL3 | 0.754455 | 3 | 0 | 3 |
| DEFB132 | SLC26A5 | 0.749456 | 3 | 0 | 3 |
| DEFB132 | CCDC144A | 0.744758 | 3 | 0 | 3 |
| DEFB132 | GSPT2 | 0.744335 | 3 | 0 | 3 |
| DEFB132 | SFTPA2 | 0.740487 | 3 | 0 | 3 |
| DEFB132 | ZNF735 | 0.739693 | 3 | 0 | 3 |
| DEFB132 | PVR | 0.731706 | 3 | 0 | 3 |
| DEFB132 | CTPS2 | 0.72507 | 4 | 0 | 3 |
| DEFB132 | TMEM63B | 0.72185 | 3 | 0 | 3 |
For details and further investigation, click here
