| Full name: surfactant protein A2 | Alias Symbol: SP-A2|COLEC5 | ||
| Type: protein-coding gene | Cytoband: 10q22.3 | ||
| Entrez ID: 729238 | HGNC ID: HGNC:10799 | Ensembl Gene: ENSG00000185303 | OMIM ID: 178642 |
| Drug and gene relationship at DGIdb | |||
Expression of SFTPA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SFTPA2 | 729238 | 154421 | -0.1110 | 0.3095 | |
| GSE53624 | SFTPA2 | 729238 | 154421 | -0.4804 | 0.0002 | |
| GSE97050 | SFTPA2 | 729238 | A_33_P3344574 | -0.1573 | 0.4438 | |
| TCGA | SFTPA2 | 729238 | RNAseq | -1.0151 | 0.2374 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SFTPA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFTPA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFTPA2 | 729238 | 2 | 5 | 23 | |
| GSE20123 | SFTPA2 | 729238 | 2 | 4 | 24 | |
| GSE43470 | SFTPA2 | 729238 | 1 | 7 | 35 | |
| GSE46452 | SFTPA2 | 729238 | 0 | 11 | 48 | |
| GSE47630 | SFTPA2 | 729238 | 2 | 14 | 24 | |
| GSE54993 | SFTPA2 | 729238 | 7 | 0 | 63 | |
| GSE54994 | SFTPA2 | 729238 | 1 | 11 | 41 | |
| GSE60625 | SFTPA2 | 729238 | 0 | 0 | 11 | |
| GSE74703 | SFTPA2 | 729238 | 1 | 4 | 31 | |
| GSE74704 | SFTPA2 | 729238 | 1 | 2 | 17 | |
| TCGA | SFTPA2 | 729238 | 10 | 24 | 62 |
Total number of gains: 27; Total number of losses: 82; Total Number of normals: 379.
Somatic mutations of SFTPA2:
Generating mutation plots.
Highly correlated genes for SFTPA2:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFTPA2 | SPSB4 | 0.894583 | 3 | 0 | 3 |
| SFTPA2 | ENTPD2 | 0.822818 | 3 | 0 | 3 |
| SFTPA2 | KRTAP21-2 | 0.8013 | 3 | 0 | 3 |
| SFTPA2 | KIR3DL2 | 0.788654 | 3 | 0 | 3 |
| SFTPA2 | CYP26C1 | 0.783328 | 3 | 0 | 3 |
| SFTPA2 | KRTAP9-6 | 0.779737 | 3 | 0 | 3 |
| SFTPA2 | CNTNAP1 | 0.769117 | 3 | 0 | 3 |
| SFTPA2 | ACRBP | 0.768224 | 3 | 0 | 3 |
| SFTPA2 | TMEM53 | 0.768013 | 3 | 0 | 3 |
| SFTPA2 | CCIN | 0.766026 | 3 | 0 | 3 |
| SFTPA2 | HES6 | 0.760853 | 3 | 0 | 3 |
| SFTPA2 | CTPS2 | 0.75746 | 3 | 0 | 3 |
| SFTPA2 | SLC11A1 | 0.756963 | 3 | 0 | 3 |
| SFTPA2 | VAX2 | 0.756279 | 3 | 0 | 3 |
| SFTPA2 | CELA3A | 0.752313 | 3 | 0 | 3 |
| SFTPA2 | CDH24 | 0.746219 | 3 | 0 | 3 |
| SFTPA2 | SLC38A7 | 0.745628 | 3 | 0 | 3 |
| SFTPA2 | TMEM150A | 0.744843 | 3 | 0 | 3 |
| SFTPA2 | ARHGAP33 | 0.744195 | 3 | 0 | 3 |
| SFTPA2 | C12orf50 | 0.743209 | 3 | 0 | 3 |
For details and further investigation, click here
