| Full name: transmembrane protein 63B | Alias Symbol: DKFZp434P0531|dJ421H19.2 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 55362 | HGNC ID: HGNC:17735 | Ensembl Gene: ENSG00000137216 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM63B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM63B | 55362 | 225271_at | 0.5845 | 0.0355 | |
| GSE26886 | TMEM63B | 55362 | 225271_at | 0.0894 | 0.5130 | |
| GSE45670 | TMEM63B | 55362 | 225271_at | 0.3732 | 0.0003 | |
| GSE53622 | TMEM63B | 55362 | 22529 | 0.2195 | 0.0001 | |
| GSE53624 | TMEM63B | 55362 | 22529 | 0.1718 | 0.0279 | |
| GSE63941 | TMEM63B | 55362 | 225271_at | 0.0623 | 0.8239 | |
| GSE77861 | TMEM63B | 55362 | 225271_at | 0.2467 | 0.0331 | |
| GSE97050 | TMEM63B | 55362 | A_23_P167856 | 0.0519 | 0.8319 | |
| SRP007169 | TMEM63B | 55362 | RNAseq | -0.7299 | 0.0856 | |
| SRP008496 | TMEM63B | 55362 | RNAseq | -0.8070 | 0.0013 | |
| SRP064894 | TMEM63B | 55362 | RNAseq | 0.3598 | 0.0604 | |
| SRP133303 | TMEM63B | 55362 | RNAseq | 0.3639 | 0.0676 | |
| SRP159526 | TMEM63B | 55362 | RNAseq | 0.3917 | 0.1046 | |
| SRP193095 | TMEM63B | 55362 | RNAseq | 0.1019 | 0.5087 | |
| SRP219564 | TMEM63B | 55362 | RNAseq | 0.2918 | 0.4313 | |
| TCGA | TMEM63B | 55362 | RNAseq | 0.0839 | 0.1638 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM63B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM63B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM63B | 55362 | 8 | 0 | 22 | |
| GSE20123 | TMEM63B | 55362 | 8 | 0 | 22 | |
| GSE43470 | TMEM63B | 55362 | 6 | 0 | 37 | |
| GSE46452 | TMEM63B | 55362 | 3 | 9 | 47 | |
| GSE47630 | TMEM63B | 55362 | 8 | 4 | 28 | |
| GSE54993 | TMEM63B | 55362 | 3 | 2 | 65 | |
| GSE54994 | TMEM63B | 55362 | 10 | 4 | 39 | |
| GSE60625 | TMEM63B | 55362 | 0 | 1 | 10 | |
| GSE74703 | TMEM63B | 55362 | 6 | 0 | 30 | |
| GSE74704 | TMEM63B | 55362 | 4 | 0 | 16 | |
| TCGA | TMEM63B | 55362 | 21 | 12 | 63 |
Total number of gains: 77; Total number of losses: 32; Total Number of normals: 379.
Somatic mutations of TMEM63B:
Generating mutation plots.
Highly correlated genes for TMEM63B:
Showing top 20/1005 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM63B | KRTAP12-2 | 0.820939 | 3 | 0 | 3 |
| TMEM63B | TP53I13 | 0.82021 | 3 | 0 | 3 |
| TMEM63B | MAN2B1 | 0.808625 | 3 | 0 | 3 |
| TMEM63B | NONO | 0.806119 | 3 | 0 | 3 |
| TMEM63B | GMEB2 | 0.805912 | 3 | 0 | 3 |
| TMEM63B | SSBP4 | 0.802581 | 3 | 0 | 3 |
| TMEM63B | RAB15 | 0.799861 | 3 | 0 | 3 |
| TMEM63B | UTP20 | 0.797142 | 3 | 0 | 3 |
| TMEM63B | LDB1 | 0.795128 | 4 | 0 | 4 |
| TMEM63B | HAUS7 | 0.794579 | 3 | 0 | 3 |
| TMEM63B | ZNF496 | 0.792261 | 3 | 0 | 3 |
| TMEM63B | SMYD2 | 0.790929 | 3 | 0 | 3 |
| TMEM63B | MED9 | 0.789933 | 3 | 0 | 3 |
| TMEM63B | KPNA1 | 0.789721 | 3 | 0 | 3 |
| TMEM63B | ALG11 | 0.786759 | 3 | 0 | 3 |
| TMEM63B | THADA | 0.784378 | 3 | 0 | 3 |
| TMEM63B | CHERP | 0.78372 | 3 | 0 | 3 |
| TMEM63B | SENP5 | 0.783549 | 3 | 0 | 3 |
| TMEM63B | ELFN1 | 0.782669 | 3 | 0 | 3 |
| TMEM63B | HOXD13 | 0.782006 | 3 | 0 | 3 |
For details and further investigation, click here
