| Full name: PVR cell adhesion molecule | Alias Symbol: CD155|HVED|Necl-5|NECL5|Tage4 | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 5817 | HGNC ID: HGNC:9705 | Ensembl Gene: ENSG00000073008 | OMIM ID: 173850 |
| Drug and gene relationship at DGIdb | |||
Expression of PVR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PVR | 5817 | 1556582_at | 0.1527 | 0.6045 | |
| GSE20347 | PVR | 5817 | 214444_s_at | -0.1287 | 0.0794 | |
| GSE23400 | PVR | 5817 | 32699_s_at | -0.2304 | 0.0000 | |
| GSE26886 | PVR | 5817 | 1556582_at | 0.0486 | 0.7589 | |
| GSE29001 | PVR | 5817 | 32699_s_at | -0.2333 | 0.0433 | |
| GSE38129 | PVR | 5817 | 212662_at | 0.5715 | 0.0004 | |
| GSE45670 | PVR | 5817 | 1556582_at | 0.0979 | 0.2203 | |
| GSE53622 | PVR | 5817 | 1251 | 0.8639 | 0.0000 | |
| GSE53624 | PVR | 5817 | 58593 | 1.2712 | 0.0000 | |
| GSE63941 | PVR | 5817 | 1556582_at | -0.3104 | 0.3049 | |
| GSE77861 | PVR | 5817 | 1556582_at | -0.1086 | 0.4136 | |
| GSE97050 | PVR | 5817 | A_23_P141894 | 0.5246 | 0.1905 | |
| SRP007169 | PVR | 5817 | RNAseq | 0.6280 | 0.1435 | |
| SRP008496 | PVR | 5817 | RNAseq | 1.0679 | 0.0007 | |
| SRP064894 | PVR | 5817 | RNAseq | 1.0787 | 0.0000 | |
| SRP133303 | PVR | 5817 | RNAseq | 1.1622 | 0.0001 | |
| SRP159526 | PVR | 5817 | RNAseq | 0.7518 | 0.0045 | |
| SRP193095 | PVR | 5817 | RNAseq | 0.9525 | 0.0000 | |
| SRP219564 | PVR | 5817 | RNAseq | 0.6041 | 0.1372 | |
| TCGA | PVR | 5817 | RNAseq | -0.0176 | 0.7928 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by PVR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PVR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PVR | 5817 | 3 | 5 | 22 | |
| GSE20123 | PVR | 5817 | 3 | 4 | 23 | |
| GSE43470 | PVR | 5817 | 3 | 11 | 29 | |
| GSE46452 | PVR | 5817 | 45 | 1 | 13 | |
| GSE47630 | PVR | 5817 | 8 | 6 | 26 | |
| GSE54993 | PVR | 5817 | 17 | 4 | 49 | |
| GSE54994 | PVR | 5817 | 6 | 12 | 35 | |
| GSE60625 | PVR | 5817 | 9 | 0 | 2 | |
| GSE74703 | PVR | 5817 | 3 | 7 | 26 | |
| GSE74704 | PVR | 5817 | 3 | 2 | 15 | |
| TCGA | PVR | 5817 | 15 | 16 | 65 |
Total number of gains: 115; Total number of losses: 68; Total Number of normals: 305.
Somatic mutations of PVR:
Generating mutation plots.
Highly correlated genes for PVR:
Showing top 20/235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PVR | TSHR | 0.751372 | 4 | 0 | 4 |
| PVR | WDR54 | 0.736172 | 3 | 0 | 3 |
| PVR | FAM89A | 0.735024 | 3 | 0 | 3 |
| PVR | DEFB132 | 0.731706 | 3 | 0 | 3 |
| PVR | TOMM40L | 0.727401 | 3 | 0 | 3 |
| PVR | ZBTB2 | 0.704197 | 4 | 0 | 4 |
| PVR | YIPF4 | 0.703824 | 3 | 0 | 3 |
| PVR | NDUFS6 | 0.70108 | 3 | 0 | 3 |
| PVR | ZNF707 | 0.700463 | 4 | 0 | 4 |
| PVR | BIN2 | 0.699966 | 3 | 0 | 3 |
| PVR | MMP3 | 0.697929 | 5 | 0 | 5 |
| PVR | SLC35B2 | 0.690956 | 3 | 0 | 3 |
| PVR | LRRC8C | 0.690042 | 3 | 0 | 3 |
| PVR | B3GNT9 | 0.684858 | 4 | 0 | 4 |
| PVR | NDEL1 | 0.682183 | 3 | 0 | 3 |
| PVR | FADS1 | 0.681995 | 3 | 0 | 3 |
| PVR | GMEB2 | 0.679887 | 4 | 0 | 4 |
| PVR | GADD45A | 0.67818 | 3 | 0 | 3 |
| PVR | EBNA1BP2 | 0.677447 | 3 | 0 | 3 |
| PVR | SERPIND1 | 0.675964 | 3 | 0 | 3 |
For details and further investigation, click here
