| Full name: olfactory receptor family 2 subfamily AT member 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 341152 | HGNC ID: HGNC:19620 | Ensembl Gene: ENSG00000171561 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR2AT4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR2AT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR2AT4 | 341152 | 51838 | 0.3682 | 0.0152 | |
| GSE53624 | OR2AT4 | 341152 | 51838 | 0.4169 | 0.0003 | |
| GSE97050 | OR2AT4 | 341152 | A_33_P3365621 | 0.1685 | 0.4701 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR2AT4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR2AT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR2AT4 | 341152 | 6 | 8 | 16 | |
| GSE20123 | OR2AT4 | 341152 | 6 | 7 | 17 | |
| GSE43470 | OR2AT4 | 341152 | 5 | 4 | 34 | |
| GSE46452 | OR2AT4 | 341152 | 7 | 22 | 30 | |
| GSE47630 | OR2AT4 | 341152 | 6 | 14 | 20 | |
| GSE54993 | OR2AT4 | 341152 | 8 | 2 | 60 | |
| GSE54994 | OR2AT4 | 341152 | 7 | 16 | 30 | |
| GSE60625 | OR2AT4 | 341152 | 4 | 3 | 4 | |
| GSE74703 | OR2AT4 | 341152 | 4 | 3 | 29 | |
| GSE74704 | OR2AT4 | 341152 | 4 | 3 | 13 | |
| TCGA | OR2AT4 | 341152 | 21 | 33 | 42 |
Total number of gains: 78; Total number of losses: 115; Total Number of normals: 295.
Somatic mutations of OR2AT4:
Generating mutation plots.
Highly correlated genes for OR2AT4:
Showing top 20/89 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR2AT4 | CCIN | 0.851888 | 3 | 0 | 3 |
| OR2AT4 | GRIA4 | 0.846107 | 3 | 0 | 3 |
| OR2AT4 | OR2T33 | 0.839732 | 3 | 0 | 3 |
| OR2AT4 | CDH24 | 0.833438 | 3 | 0 | 3 |
| OR2AT4 | SZT2 | 0.828488 | 3 | 0 | 3 |
| OR2AT4 | ZNF445 | 0.817529 | 3 | 0 | 3 |
| OR2AT4 | ZNF248 | 0.815695 | 3 | 0 | 3 |
| OR2AT4 | DEFB132 | 0.814368 | 3 | 0 | 3 |
| OR2AT4 | TIGD1 | 0.810667 | 3 | 0 | 3 |
| OR2AT4 | CTPS2 | 0.808074 | 3 | 0 | 3 |
| OR2AT4 | ARHGEF33 | 0.804886 | 3 | 0 | 3 |
| OR2AT4 | ALG11 | 0.795064 | 3 | 0 | 3 |
| OR2AT4 | CELA3A | 0.785659 | 3 | 0 | 3 |
| OR2AT4 | CCDC154 | 0.78558 | 3 | 0 | 3 |
| OR2AT4 | TP53AIP1 | 0.780847 | 3 | 0 | 3 |
| OR2AT4 | SLC4A8 | 0.7808 | 3 | 0 | 3 |
| OR2AT4 | SLC6A2 | 0.775143 | 3 | 0 | 3 |
| OR2AT4 | KRTAP10-4 | 0.771383 | 3 | 0 | 3 |
| OR2AT4 | APOB | 0.765048 | 3 | 0 | 3 |
| OR2AT4 | SLC26A5 | 0.75005 | 3 | 0 | 3 |
For details and further investigation, click here
