| Full name: solute carrier family 26 member 5 | Alias Symbol: DFNB61 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 375611 | HGNC ID: HGNC:9359 | Ensembl Gene: ENSG00000170615 | OMIM ID: 604943 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC26A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SLC26A5 | 375611 | 128624 | 0.4764 | 0.0000 | |
| GSE53624 | SLC26A5 | 375611 | 128624 | 0.2648 | 0.0001 | |
| GSE97050 | SLC26A5 | 375611 | A_33_P3400699 | 0.0841 | 0.6542 | |
| SRP133303 | SLC26A5 | 375611 | RNAseq | 1.1412 | 0.0123 | |
| SRP159526 | SLC26A5 | 375611 | RNAseq | 2.3952 | 0.0109 | |
| TCGA | SLC26A5 | 375611 | RNAseq | -0.9955 | 0.0984 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC26A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC26A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC26A5 | 375611 | 13 | 0 | 17 | |
| GSE20123 | SLC26A5 | 375611 | 13 | 0 | 17 | |
| GSE43470 | SLC26A5 | 375611 | 6 | 1 | 36 | |
| GSE46452 | SLC26A5 | 375611 | 10 | 1 | 48 | |
| GSE47630 | SLC26A5 | 375611 | 7 | 3 | 30 | |
| GSE54993 | SLC26A5 | 375611 | 1 | 10 | 59 | |
| GSE54994 | SLC26A5 | 375611 | 16 | 3 | 34 | |
| GSE60625 | SLC26A5 | 375611 | 0 | 0 | 11 | |
| GSE74703 | SLC26A5 | 375611 | 6 | 1 | 29 | |
| GSE74704 | SLC26A5 | 375611 | 9 | 0 | 11 | |
| TCGA | SLC26A5 | 375611 | 54 | 6 | 36 |
Total number of gains: 135; Total number of losses: 25; Total Number of normals: 328.
Somatic mutations of SLC26A5:
Generating mutation plots.
Highly correlated genes for SLC26A5:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC26A5 | CCDC154 | 0.861163 | 3 | 0 | 3 |
| SLC26A5 | ZNF248 | 0.847428 | 3 | 0 | 3 |
| SLC26A5 | GRIA4 | 0.840596 | 3 | 0 | 3 |
| SLC26A5 | SZT2 | 0.830881 | 3 | 0 | 3 |
| SLC26A5 | CTPS2 | 0.821439 | 3 | 0 | 3 |
| SLC26A5 | KRTAP12-2 | 0.819536 | 3 | 0 | 3 |
| SLC26A5 | ALG11 | 0.819326 | 3 | 0 | 3 |
| SLC26A5 | CDH24 | 0.813866 | 3 | 0 | 3 |
| SLC26A5 | NRL | 0.806 | 3 | 0 | 3 |
| SLC26A5 | ARTN | 0.799347 | 3 | 0 | 3 |
| SLC26A5 | OR2T33 | 0.797562 | 3 | 0 | 3 |
| SLC26A5 | CELA3A | 0.797188 | 3 | 0 | 3 |
| SLC26A5 | CCIN | 0.793253 | 3 | 0 | 3 |
| SLC26A5 | ANKRD65 | 0.78999 | 3 | 0 | 3 |
| SLC26A5 | ZNF445 | 0.784124 | 3 | 0 | 3 |
| SLC26A5 | KLF16 | 0.774739 | 3 | 0 | 3 |
| SLC26A5 | SLC38A6 | 0.773199 | 3 | 0 | 3 |
| SLC26A5 | RBM17 | 0.769579 | 3 | 0 | 3 |
| SLC26A5 | KLHL17 | 0.767546 | 3 | 0 | 3 |
| SLC26A5 | CALY | 0.767526 | 3 | 0 | 3 |
For details and further investigation, click here
