FAM205A

 

Full name: family with sequence similarity 205 member A Alias Symbol: C9orf144B
Type: protein-coding gene Cytoband: 9p13.3
Entrez ID: 259308 HGNC ID: HGNC:41911 Ensembl Gene: ENSG00000205108 OMIM ID: 
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of FAM205A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FAM205A 259308 243270_at -0.2065 0.3680
GSE26886 FAM205A 259308 243270_at 0.0196 0.8815
GSE45670 FAM205A 259308 243270_at 0.1214 0.1446
GSE53622 FAM205A 259308 54772 0.1775 0.0189
GSE53624 FAM205A 259308 54772 0.2876 0.0010
GSE63941 FAM205A 259308 243270_at 0.3654 0.0169
GSE77861 FAM205A 259308 243270_at -0.1041 0.3315

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by FAM205A expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of FAM205A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FAM205A 259308 4 13 13
GSE20123 FAM205A 259308 4 13 13
GSE43470 FAM205A 259308 3 10 30
GSE46452 FAM205A 259308 6 15 38
GSE47630 FAM205A 259308 1 20 19
GSE54993 FAM205A 259308 6 0 64
GSE54994 FAM205A 259308 6 12 35
GSE60625 FAM205A 259308 0 0 11
GSE74703 FAM205A 259308 2 7 27
GSE74704 FAM205A 259308 0 11 9
TCGA FAM205A 259308 16 44 36

Total number of gains: 48; Total number of losses: 145; Total Number of normals: 295.  


 

Somatic mutations of FAM205A:

 

Generating mutation plots.

 

Highly correlated genes for FAM205A:

 

Showing top 20/236 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FAM205AGRIA40.758924303
FAM205ALINC009170.743502303
FAM205ALINC002710.737684303
FAM205ALIPE-AS10.734533303
FAM205AHIPK1-AS10.728739303
FAM205ALINC013500.714715404
FAM205ADSCAM-AS10.713823303
FAM205ATRIM100.712034303
FAM205ARAPGEF30.710834303
FAM205ASLC22A110.70893303
FAM205ACOX6A20.701692303
FAM205AKLF170.696988404
FAM205AKRTAP4-80.696666505
FAM205APLA2G2D0.691363303
FAM205ACCDC630.687032303
FAM205AZBTB46-AS10.685011303
FAM205ABARHL10.683662505
FAM205AMUC20.677105303
FAM205ASLC26A10.670087404
FAM205AFAM222A-AS10.670024404

For details and further investigation, click here