| Full name: solute carrier family 22 member 11 | Alias Symbol: OAT4 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 55867 | HGNC ID: HGNC:18120 | Ensembl Gene: ENSG00000168065 | OMIM ID: 607097 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC22A11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC22A11 | 55867 | 220100_at | 0.1957 | 0.5862 | |
| GSE20347 | SLC22A11 | 55867 | 220100_at | -0.0498 | 0.3263 | |
| GSE23400 | SLC22A11 | 55867 | 220100_at | -0.1803 | 0.0001 | |
| GSE26886 | SLC22A11 | 55867 | 220100_at | 0.1522 | 0.1742 | |
| GSE29001 | SLC22A11 | 55867 | 220100_at | -0.1454 | 0.2809 | |
| GSE38129 | SLC22A11 | 55867 | 220100_at | -0.0552 | 0.3980 | |
| GSE45670 | SLC22A11 | 55867 | 220100_at | 0.2227 | 0.0085 | |
| GSE53622 | SLC22A11 | 55867 | 75915 | 0.3244 | 0.0015 | |
| GSE53624 | SLC22A11 | 55867 | 75915 | 0.3065 | 0.0004 | |
| GSE63941 | SLC22A11 | 55867 | 220100_at | 0.2681 | 0.2481 | |
| GSE77861 | SLC22A11 | 55867 | 220100_at | -0.1182 | 0.4902 | |
| GSE97050 | SLC22A11 | 55867 | A_23_P47199 | -0.0051 | 0.9848 | |
| TCGA | SLC22A11 | 55867 | RNAseq | 3.1076 | 0.0016 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC22A11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC22A11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC22A11 | 55867 | 7 | 5 | 18 | |
| GSE20123 | SLC22A11 | 55867 | 7 | 5 | 18 | |
| GSE43470 | SLC22A11 | 55867 | 1 | 3 | 39 | |
| GSE46452 | SLC22A11 | 55867 | 8 | 4 | 47 | |
| GSE47630 | SLC22A11 | 55867 | 4 | 6 | 30 | |
| GSE54993 | SLC22A11 | 55867 | 3 | 1 | 66 | |
| GSE54994 | SLC22A11 | 55867 | 6 | 5 | 42 | |
| GSE60625 | SLC22A11 | 55867 | 0 | 3 | 8 | |
| GSE74703 | SLC22A11 | 55867 | 1 | 1 | 34 | |
| GSE74704 | SLC22A11 | 55867 | 5 | 3 | 12 | |
| TCGA | SLC22A11 | 55867 | 21 | 9 | 66 |
Total number of gains: 63; Total number of losses: 45; Total Number of normals: 380.
Somatic mutations of SLC22A11:
Generating mutation plots.
Highly correlated genes for SLC22A11:
Showing top 20/928 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC22A11 | STRC | 0.8246 | 3 | 0 | 3 |
| SLC22A11 | DEFB128 | 0.803499 | 3 | 0 | 3 |
| SLC22A11 | CHST10 | 0.802728 | 3 | 0 | 3 |
| SLC22A11 | OR2A5 | 0.802048 | 3 | 0 | 3 |
| SLC22A11 | OR2T1 | 0.799726 | 3 | 0 | 3 |
| SLC22A11 | DCDC1 | 0.79832 | 3 | 0 | 3 |
| SLC22A11 | OR2T27 | 0.794405 | 3 | 0 | 3 |
| SLC22A11 | PLA2G2C | 0.787878 | 3 | 0 | 3 |
| SLC22A11 | BBC3 | 0.777734 | 3 | 0 | 3 |
| SLC22A11 | OR1J4 | 0.7768 | 3 | 0 | 3 |
| SLC22A11 | TNFAIP8L1 | 0.773015 | 3 | 0 | 3 |
| SLC22A11 | C9orf153 | 0.769324 | 3 | 0 | 3 |
| SLC22A11 | C19orf71 | 0.766913 | 3 | 0 | 3 |
| SLC22A11 | CDK16 | 0.766642 | 3 | 0 | 3 |
| SLC22A11 | NRSN1 | 0.758041 | 3 | 0 | 3 |
| SLC22A11 | MRGPRG | 0.754879 | 3 | 0 | 3 |
| SLC22A11 | OR4D6 | 0.754415 | 3 | 0 | 3 |
| SLC22A11 | YY2 | 0.751956 | 3 | 0 | 3 |
| SLC22A11 | LRRC30 | 0.751798 | 3 | 0 | 3 |
| SLC22A11 | ELOVL3 | 0.751484 | 3 | 0 | 3 |
For details and further investigation, click here
