| Full name: mucin 2, oligomeric mucus/gel-forming | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 4583 | HGNC ID: HGNC:7512 | Ensembl Gene: ENSG00000198788 | OMIM ID: 158370 |
| Drug and gene relationship at DGIdb | |||
Expression of MUC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MUC2 | 4583 | 204673_at | -0.2512 | 0.3592 | |
| GSE20347 | MUC2 | 4583 | 204673_at | 0.0336 | 0.6774 | |
| GSE23400 | MUC2 | 4583 | 204673_at | -0.0880 | 0.0139 | |
| GSE26886 | MUC2 | 4583 | 204673_at | 0.3410 | 0.0010 | |
| GSE29001 | MUC2 | 4583 | 204673_at | 0.0151 | 0.9395 | |
| GSE38129 | MUC2 | 4583 | 204673_at | -0.0252 | 0.7946 | |
| GSE45670 | MUC2 | 4583 | 204673_at | 0.1427 | 0.0950 | |
| GSE53622 | MUC2 | 4583 | 30921 | -0.2683 | 0.0000 | |
| GSE53624 | MUC2 | 4583 | 135008 | -0.1893 | 0.0631 | |
| GSE63941 | MUC2 | 4583 | 204673_at | 0.1622 | 0.3389 | |
| GSE77861 | MUC2 | 4583 | 204673_at | -0.0910 | 0.3774 | |
| GSE97050 | MUC2 | 4583 | A_23_P256784 | 0.1434 | 0.4808 | |
| TCGA | MUC2 | 4583 | RNAseq | 2.0611 | 0.0186 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MUC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MUC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MUC2 | 4583 | 1 | 11 | 18 | |
| GSE20123 | MUC2 | 4583 | 1 | 12 | 17 | |
| GSE43470 | MUC2 | 4583 | 1 | 10 | 32 | |
| GSE46452 | MUC2 | 4583 | 7 | 8 | 44 | |
| GSE47630 | MUC2 | 4583 | 4 | 12 | 24 | |
| GSE54993 | MUC2 | 4583 | 3 | 1 | 66 | |
| GSE54994 | MUC2 | 4583 | 1 | 12 | 40 | |
| GSE60625 | MUC2 | 4583 | 0 | 0 | 11 | |
| GSE74703 | MUC2 | 4583 | 1 | 8 | 27 | |
| GSE74704 | MUC2 | 4583 | 0 | 8 | 12 | |
| TCGA | MUC2 | 4583 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of MUC2:
Generating mutation plots.
Highly correlated genes for MUC2:
Showing top 20/1048 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MUC2 | GDF7 | 0.794066 | 3 | 0 | 3 |
| MUC2 | C16orf82 | 0.79196 | 3 | 0 | 3 |
| MUC2 | PROCA1 | 0.787296 | 3 | 0 | 3 |
| MUC2 | SP7 | 0.780027 | 3 | 0 | 3 |
| MUC2 | ZSCAN16-AS1 | 0.772628 | 3 | 0 | 3 |
| MUC2 | NKX6-3 | 0.770108 | 3 | 0 | 3 |
| MUC2 | KRT74 | 0.746667 | 3 | 0 | 3 |
| MUC2 | CLCNKA | 0.743285 | 3 | 0 | 3 |
| MUC2 | TMEM235 | 0.742755 | 3 | 0 | 3 |
| MUC2 | CRB2 | 0.741968 | 3 | 0 | 3 |
| MUC2 | TSKS | 0.740063 | 4 | 0 | 4 |
| MUC2 | STXBP6 | 0.733262 | 3 | 0 | 3 |
| MUC2 | PLA2G12B | 0.733064 | 3 | 0 | 3 |
| MUC2 | STX1B | 0.732179 | 4 | 0 | 3 |
| MUC2 | RAB11FIP4 | 0.731071 | 3 | 0 | 3 |
| MUC2 | ZAN | 0.724317 | 4 | 0 | 4 |
| MUC2 | BSND | 0.724154 | 4 | 0 | 3 |
| MUC2 | CTU1 | 0.724105 | 3 | 0 | 3 |
| MUC2 | SNED1 | 0.723949 | 4 | 0 | 3 |
| MUC2 | TAS2R40 | 0.720928 | 3 | 0 | 3 |
For details and further investigation, click here
