| Full name: phospholipase A2 group IID | Alias Symbol: sPLA2S | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 26279 | HGNC ID: HGNC:9033 | Ensembl Gene: ENSG00000117215 | OMIM ID: 605630 |
| Drug and gene relationship at DGIdb | |||
PLA2G2D involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04014 | Ras signaling pathway | |
| hsa04270 | Vascular smooth muscle contraction |
Expression of PLA2G2D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLA2G2D | 26279 | 220423_at | 0.1704 | 0.7856 | |
| GSE20347 | PLA2G2D | 26279 | 220423_at | 0.1531 | 0.2050 | |
| GSE23400 | PLA2G2D | 26279 | 220423_at | -0.0400 | 0.3894 | |
| GSE26886 | PLA2G2D | 26279 | 220423_at | 0.1084 | 0.4144 | |
| GSE29001 | PLA2G2D | 26279 | 220423_at | -0.1272 | 0.4520 | |
| GSE38129 | PLA2G2D | 26279 | 220423_at | -0.0120 | 0.9420 | |
| GSE45670 | PLA2G2D | 26279 | 220423_at | 0.0270 | 0.8361 | |
| GSE53622 | PLA2G2D | 26279 | 36305 | 0.1136 | 0.1145 | |
| GSE53624 | PLA2G2D | 26279 | 36305 | 0.0012 | 0.9926 | |
| GSE63941 | PLA2G2D | 26279 | 220423_at | 0.1220 | 0.4793 | |
| GSE77861 | PLA2G2D | 26279 | 220423_at | 0.0187 | 0.8888 | |
| GSE97050 | PLA2G2D | 26279 | A_23_P300100 | 0.0624 | 0.7804 | |
| SRP133303 | PLA2G2D | 26279 | RNAseq | 0.1674 | 0.5703 | |
| SRP159526 | PLA2G2D | 26279 | RNAseq | -0.3403 | 0.7602 | |
| SRP193095 | PLA2G2D | 26279 | RNAseq | 0.0707 | 0.7091 | |
| SRP219564 | PLA2G2D | 26279 | RNAseq | 0.7430 | 0.2616 | |
| TCGA | PLA2G2D | 26279 | RNAseq | -0.0634 | 0.9197 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PLA2G2D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLA2G2D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLA2G2D | 26279 | 0 | 5 | 25 | |
| GSE20123 | PLA2G2D | 26279 | 0 | 4 | 26 | |
| GSE43470 | PLA2G2D | 26279 | 0 | 8 | 35 | |
| GSE46452 | PLA2G2D | 26279 | 5 | 1 | 53 | |
| GSE47630 | PLA2G2D | 26279 | 8 | 3 | 29 | |
| GSE54993 | PLA2G2D | 26279 | 3 | 1 | 66 | |
| GSE54994 | PLA2G2D | 26279 | 11 | 4 | 38 | |
| GSE60625 | PLA2G2D | 26279 | 0 | 0 | 11 | |
| GSE74703 | PLA2G2D | 26279 | 0 | 5 | 31 | |
| GSE74704 | PLA2G2D | 26279 | 0 | 0 | 20 | |
| TCGA | PLA2G2D | 26279 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of PLA2G2D:
Generating mutation plots.
Highly correlated genes for PLA2G2D:
Showing top 20/690 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLA2G2D | YY2 | 0.880637 | 3 | 0 | 3 |
| PLA2G2D | OR2T27 | 0.869915 | 3 | 0 | 3 |
| PLA2G2D | DEFB121 | 0.86731 | 3 | 0 | 3 |
| PLA2G2D | DCDC1 | 0.86126 | 3 | 0 | 3 |
| PLA2G2D | FBRSL1 | 0.842299 | 3 | 0 | 3 |
| PLA2G2D | C1QL2 | 0.840765 | 3 | 0 | 3 |
| PLA2G2D | PRSS38 | 0.828481 | 3 | 0 | 3 |
| PLA2G2D | OR2T1 | 0.824964 | 3 | 0 | 3 |
| PLA2G2D | OR2A5 | 0.822948 | 3 | 0 | 3 |
| PLA2G2D | BBC3 | 0.821122 | 3 | 0 | 3 |
| PLA2G2D | STRC | 0.809657 | 3 | 0 | 3 |
| PLA2G2D | POLM | 0.805314 | 4 | 0 | 4 |
| PLA2G2D | BSX | 0.801425 | 3 | 0 | 3 |
| PLA2G2D | TMEM229A | 0.796779 | 3 | 0 | 3 |
| PLA2G2D | OTOG | 0.795125 | 3 | 0 | 3 |
| PLA2G2D | INSC | 0.7945 | 4 | 0 | 4 |
| PLA2G2D | PABPN1L | 0.789185 | 3 | 0 | 3 |
| PLA2G2D | GDF7 | 0.787076 | 3 | 0 | 3 |
| PLA2G2D | ZNF329 | 0.783992 | 3 | 0 | 3 |
| PLA2G2D | SPN | 0.780447 | 4 | 0 | 4 |
For details and further investigation, click here
