| Full name: F-box and leucine rich repeat protein 13 | Alias Symbol: MGC21636|Fbl13|DRC6 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 222235 | HGNC ID: HGNC:21658 | Ensembl Gene: ENSG00000161040 | OMIM ID: 609080 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXL13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXL13 | 222235 | 1553798_a_at | -0.1452 | 0.7207 | |
| GSE26886 | FBXL13 | 222235 | 1553798_a_at | 0.3244 | 0.0520 | |
| GSE45670 | FBXL13 | 222235 | 1556770_a_at | -0.0750 | 0.6208 | |
| GSE53622 | FBXL13 | 222235 | 155651 | 0.3714 | 0.0865 | |
| GSE53624 | FBXL13 | 222235 | 155651 | 0.1678 | 0.3511 | |
| GSE63941 | FBXL13 | 222235 | 1553798_a_at | -0.2347 | 0.5938 | |
| GSE77861 | FBXL13 | 222235 | 1556770_a_at | -0.0934 | 0.3224 | |
| GSE97050 | FBXL13 | 222235 | A_23_P379071 | 0.5171 | 0.3552 | |
| SRP133303 | FBXL13 | 222235 | RNAseq | 0.0734 | 0.5958 | |
| SRP193095 | FBXL13 | 222235 | RNAseq | -0.0246 | 0.9307 | |
| TCGA | FBXL13 | 222235 | RNAseq | -1.8909 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FBXL13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXL13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXL13 | 222235 | 13 | 0 | 17 | |
| GSE20123 | FBXL13 | 222235 | 13 | 0 | 17 | |
| GSE43470 | FBXL13 | 222235 | 6 | 3 | 34 | |
| GSE46452 | FBXL13 | 222235 | 10 | 1 | 48 | |
| GSE47630 | FBXL13 | 222235 | 7 | 3 | 30 | |
| GSE54993 | FBXL13 | 222235 | 1 | 10 | 59 | |
| GSE54994 | FBXL13 | 222235 | 15 | 3 | 35 | |
| GSE60625 | FBXL13 | 222235 | 0 | 0 | 11 | |
| GSE74703 | FBXL13 | 222235 | 6 | 2 | 28 | |
| GSE74704 | FBXL13 | 222235 | 9 | 0 | 11 | |
| TCGA | FBXL13 | 222235 | 53 | 6 | 37 |
Total number of gains: 133; Total number of losses: 28; Total Number of normals: 327.
Somatic mutations of FBXL13:
Generating mutation plots.
Highly correlated genes for FBXL13:
Showing all 12 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXL13 | NFE4 | 0.733293 | 5 | 0 | 5 |
| FBXL13 | WDR63 | 0.654934 | 3 | 0 | 3 |
| FBXL13 | C5orf47 | 0.593909 | 3 | 0 | 3 |
| FBXL13 | NR3C2 | 0.590754 | 3 | 0 | 3 |
| FBXL13 | ZNF792 | 0.557037 | 4 | 0 | 3 |
| FBXL13 | ERCC2 | 0.550375 | 3 | 0 | 3 |
| FBXL13 | TAF1L | 0.539118 | 3 | 0 | 3 |
| FBXL13 | TAGLN3 | 0.521765 | 5 | 0 | 3 |
| FBXL13 | BHLHE41 | 0.520486 | 4 | 0 | 3 |
| FBXL13 | OMA1 | 0.517629 | 3 | 0 | 3 |
| FBXL13 | SLC35G2 | 0.516275 | 3 | 0 | 3 |
| FBXL13 | BBS12 | 0.502733 | 5 | 0 | 3 |
For details and further investigation, click here
