| Full name: transgelin 3 | Alias Symbol: NP25|NP22 | ||
| Type: protein-coding gene | Cytoband: 3q13.2 | ||
| Entrez ID: 29114 | HGNC ID: HGNC:29868 | Ensembl Gene: ENSG00000144834 | OMIM ID: 607953 |
| Drug and gene relationship at DGIdb | |||
Expression of TAGLN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAGLN3 | 29114 | 204743_at | -0.2021 | 0.7308 | |
| GSE20347 | TAGLN3 | 29114 | 204743_at | 0.2432 | 0.0566 | |
| GSE23400 | TAGLN3 | 29114 | 204743_at | -0.0646 | 0.2218 | |
| GSE26886 | TAGLN3 | 29114 | 204743_at | 0.1168 | 0.3796 | |
| GSE29001 | TAGLN3 | 29114 | 204743_at | 0.1234 | 0.4538 | |
| GSE38129 | TAGLN3 | 29114 | 204743_at | 0.0771 | 0.7029 | |
| GSE45670 | TAGLN3 | 29114 | 204743_at | 0.4123 | 0.0286 | |
| GSE53622 | TAGLN3 | 29114 | 62432 | 0.9334 | 0.0000 | |
| GSE53624 | TAGLN3 | 29114 | 62432 | 1.3099 | 0.0000 | |
| GSE63941 | TAGLN3 | 29114 | 204743_at | -0.2026 | 0.4193 | |
| GSE77861 | TAGLN3 | 29114 | 204743_at | -0.0543 | 0.7445 | |
| GSE97050 | TAGLN3 | 29114 | A_23_P80817 | 0.2290 | 0.4350 | |
| TCGA | TAGLN3 | 29114 | RNAseq | -0.6180 | 0.3499 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TAGLN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAGLN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAGLN3 | 29114 | 17 | 1 | 12 | |
| GSE20123 | TAGLN3 | 29114 | 17 | 1 | 12 | |
| GSE43470 | TAGLN3 | 29114 | 20 | 1 | 22 | |
| GSE46452 | TAGLN3 | 29114 | 12 | 6 | 41 | |
| GSE47630 | TAGLN3 | 29114 | 16 | 6 | 18 | |
| GSE54993 | TAGLN3 | 29114 | 2 | 5 | 63 | |
| GSE54994 | TAGLN3 | 29114 | 29 | 4 | 20 | |
| GSE60625 | TAGLN3 | 29114 | 0 | 6 | 5 | |
| GSE74703 | TAGLN3 | 29114 | 16 | 1 | 19 | |
| GSE74704 | TAGLN3 | 29114 | 13 | 1 | 6 | |
| TCGA | TAGLN3 | 29114 | 52 | 6 | 38 |
Total number of gains: 194; Total number of losses: 38; Total Number of normals: 256.
Somatic mutations of TAGLN3:
Generating mutation plots.
Highly correlated genes for TAGLN3:
Showing top 20/289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAGLN3 | GABRA5 | 0.732494 | 3 | 0 | 3 |
| TAGLN3 | MT1M | 0.685537 | 3 | 0 | 3 |
| TAGLN3 | CNTN2 | 0.678125 | 4 | 0 | 4 |
| TAGLN3 | PTGFR | 0.675907 | 3 | 0 | 3 |
| TAGLN3 | GFRA3 | 0.674994 | 3 | 0 | 3 |
| TAGLN3 | SGK2 | 0.672116 | 4 | 0 | 4 |
| TAGLN3 | OR1F1 | 0.669889 | 6 | 0 | 5 |
| TAGLN3 | OR10H3 | 0.667329 | 4 | 0 | 4 |
| TAGLN3 | NPTX1 | 0.666795 | 5 | 0 | 4 |
| TAGLN3 | YPEL1 | 0.66407 | 3 | 0 | 3 |
| TAGLN3 | CHRM2 | 0.659949 | 5 | 0 | 5 |
| TAGLN3 | PDZD3 | 0.658802 | 4 | 0 | 3 |
| TAGLN3 | LIN7A | 0.65765 | 5 | 0 | 4 |
| TAGLN3 | SPACA1 | 0.653264 | 3 | 0 | 3 |
| TAGLN3 | ZNF334 | 0.650929 | 3 | 0 | 3 |
| TAGLN3 | NGB | 0.650097 | 4 | 0 | 4 |
| TAGLN3 | AMPH | 0.646744 | 3 | 0 | 3 |
| TAGLN3 | FRMD1 | 0.640225 | 3 | 0 | 3 |
| TAGLN3 | ECEL1 | 0.639464 | 3 | 0 | 3 |
| TAGLN3 | CLMP | 0.638598 | 4 | 0 | 3 |
For details and further investigation, click here
