| Full name: OMA1 zinc metallopeptidase | Alias Symbol: MPRP-1|YKR087C|ZMPOMA1|FLJ33782 | ||
| Type: protein-coding gene | Cytoband: 1p32.2-p32.1 | ||
| Entrez ID: 115209 | HGNC ID: HGNC:29661 | Ensembl Gene: ENSG00000162600 | OMIM ID: 617081 |
| Drug and gene relationship at DGIdb | |||
Expression of OMA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OMA1 | 115209 | 226019_at | -0.0119 | 0.9920 | |
| GSE26886 | OMA1 | 115209 | 226019_at | -0.2644 | 0.4549 | |
| GSE45670 | OMA1 | 115209 | 226019_at | 0.1483 | 0.4992 | |
| GSE53622 | OMA1 | 115209 | 6764 | -0.3821 | 0.0000 | |
| GSE53624 | OMA1 | 115209 | 117241 | -0.0837 | 0.2176 | |
| GSE63941 | OMA1 | 115209 | 226019_at | 0.1099 | 0.8284 | |
| GSE77861 | OMA1 | 115209 | 226019_at | -0.8531 | 0.0257 | |
| GSE97050 | OMA1 | 115209 | A_23_P138137 | 0.2277 | 0.3023 | |
| SRP007169 | OMA1 | 115209 | RNAseq | -0.7180 | 0.1687 | |
| SRP008496 | OMA1 | 115209 | RNAseq | -0.6933 | 0.0145 | |
| SRP064894 | OMA1 | 115209 | RNAseq | -0.2467 | 0.1611 | |
| SRP133303 | OMA1 | 115209 | RNAseq | -0.2427 | 0.3847 | |
| SRP159526 | OMA1 | 115209 | RNAseq | -0.2678 | 0.3774 | |
| SRP193095 | OMA1 | 115209 | RNAseq | -0.6301 | 0.0002 | |
| SRP219564 | OMA1 | 115209 | RNAseq | -0.4460 | 0.0495 | |
| TCGA | OMA1 | 115209 | RNAseq | -0.0826 | 0.2628 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OMA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OMA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OMA1 | 115209 | 3 | 4 | 23 | |
| GSE20123 | OMA1 | 115209 | 3 | 3 | 24 | |
| GSE43470 | OMA1 | 115209 | 8 | 1 | 34 | |
| GSE46452 | OMA1 | 115209 | 2 | 1 | 56 | |
| GSE47630 | OMA1 | 115209 | 8 | 5 | 27 | |
| GSE54993 | OMA1 | 115209 | 0 | 0 | 70 | |
| GSE54994 | OMA1 | 115209 | 8 | 2 | 43 | |
| GSE60625 | OMA1 | 115209 | 0 | 0 | 11 | |
| GSE74703 | OMA1 | 115209 | 7 | 1 | 28 | |
| GSE74704 | OMA1 | 115209 | 2 | 0 | 18 | |
| TCGA | OMA1 | 115209 | 10 | 18 | 68 |
Total number of gains: 51; Total number of losses: 35; Total Number of normals: 402.
Somatic mutations of OMA1:
Generating mutation plots.
Highly correlated genes for OMA1:
Showing top 20/385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OMA1 | GPBP1 | 0.766429 | 3 | 0 | 3 |
| OMA1 | ZNF83 | 0.749304 | 3 | 0 | 3 |
| OMA1 | ZNF91 | 0.749155 | 3 | 0 | 3 |
| OMA1 | ZNRD1 | 0.746575 | 3 | 0 | 3 |
| OMA1 | YTHDF2 | 0.740008 | 3 | 0 | 3 |
| OMA1 | CAMTA1 | 0.727216 | 3 | 0 | 3 |
| OMA1 | ZSCAN12 | 0.724261 | 3 | 0 | 3 |
| OMA1 | CMC1 | 0.724221 | 3 | 0 | 3 |
| OMA1 | PITRM1 | 0.72354 | 3 | 0 | 3 |
| OMA1 | SLAIN1 | 0.719707 | 3 | 0 | 3 |
| OMA1 | PEPD | 0.717386 | 3 | 0 | 3 |
| OMA1 | PDZD8 | 0.710216 | 3 | 0 | 3 |
| OMA1 | ZNF418 | 0.70637 | 3 | 0 | 3 |
| OMA1 | ZBTB1 | 0.704233 | 3 | 0 | 3 |
| OMA1 | KCTD6 | 0.699833 | 3 | 0 | 3 |
| OMA1 | LRMP | 0.698645 | 4 | 0 | 4 |
| OMA1 | GOT1 | 0.691381 | 3 | 0 | 3 |
| OMA1 | ZNF76 | 0.690866 | 3 | 0 | 3 |
| OMA1 | RSRC2 | 0.689762 | 3 | 0 | 3 |
| OMA1 | ZNF439 | 0.680721 | 4 | 0 | 3 |
For details and further investigation, click here
