| Full name: Bardet-Biedl syndrome 12 | Alias Symbol: FLJ35630|FLJ41559 | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 166379 | HGNC ID: HGNC:26648 | Ensembl Gene: ENSG00000181004 | OMIM ID: 610683 |
| Drug and gene relationship at DGIdb | |||
Expression of BBS12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BBS12 | 166379 | 229603_at | -0.0044 | 0.9960 | |
| GSE26886 | BBS12 | 166379 | 229603_at | -0.0492 | 0.9129 | |
| GSE45670 | BBS12 | 166379 | 229603_at | -0.0568 | 0.8691 | |
| GSE53622 | BBS12 | 166379 | 37598 | 0.1750 | 0.1348 | |
| GSE53624 | BBS12 | 166379 | 37598 | 0.4829 | 0.0000 | |
| GSE63941 | BBS12 | 166379 | 229603_at | -1.2460 | 0.0164 | |
| GSE77861 | BBS12 | 166379 | 229603_at | -0.2051 | 0.1328 | |
| GSE97050 | BBS12 | 166379 | A_32_P235796 | 0.2519 | 0.4166 | |
| SRP007169 | BBS12 | 166379 | RNAseq | 0.2211 | 0.7737 | |
| SRP064894 | BBS12 | 166379 | RNAseq | 0.4489 | 0.0207 | |
| SRP133303 | BBS12 | 166379 | RNAseq | 0.5303 | 0.0259 | |
| SRP159526 | BBS12 | 166379 | RNAseq | 0.7367 | 0.0911 | |
| SRP193095 | BBS12 | 166379 | RNAseq | -0.0179 | 0.9294 | |
| SRP219564 | BBS12 | 166379 | RNAseq | 0.0454 | 0.9222 | |
| TCGA | BBS12 | 166379 | RNAseq | -0.1492 | 0.1429 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BBS12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BBS12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BBS12 | 166379 | 0 | 13 | 17 | |
| GSE20123 | BBS12 | 166379 | 0 | 13 | 17 | |
| GSE43470 | BBS12 | 166379 | 0 | 13 | 30 | |
| GSE46452 | BBS12 | 166379 | 1 | 36 | 22 | |
| GSE47630 | BBS12 | 166379 | 0 | 22 | 18 | |
| GSE54993 | BBS12 | 166379 | 9 | 0 | 61 | |
| GSE54994 | BBS12 | 166379 | 1 | 10 | 42 | |
| GSE60625 | BBS12 | 166379 | 0 | 1 | 10 | |
| GSE74703 | BBS12 | 166379 | 0 | 11 | 25 | |
| GSE74704 | BBS12 | 166379 | 0 | 7 | 13 | |
| TCGA | BBS12 | 166379 | 8 | 35 | 53 |
Total number of gains: 19; Total number of losses: 161; Total Number of normals: 308.
Somatic mutations of BBS12:
Generating mutation plots.
Highly correlated genes for BBS12:
Showing top 20/330 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BBS12 | CD226 | 0.753721 | 3 | 0 | 3 |
| BBS12 | OSCAR | 0.738098 | 3 | 0 | 3 |
| BBS12 | GPR183 | 0.726925 | 3 | 0 | 3 |
| BBS12 | SH3GL3 | 0.708175 | 3 | 0 | 3 |
| BBS12 | NME7 | 0.707304 | 5 | 0 | 5 |
| BBS12 | SEC24D | 0.696918 | 4 | 0 | 4 |
| BBS12 | SNX7 | 0.690259 | 4 | 0 | 3 |
| BBS12 | ZNF547 | 0.688372 | 3 | 0 | 3 |
| BBS12 | PTGER4 | 0.685893 | 3 | 0 | 3 |
| BBS12 | ZNF225 | 0.685376 | 3 | 0 | 3 |
| BBS12 | EID2B | 0.679878 | 4 | 0 | 4 |
| BBS12 | MMP16 | 0.679055 | 4 | 0 | 3 |
| BBS12 | ZBTB25 | 0.67644 | 4 | 0 | 3 |
| BBS12 | TRIM32 | 0.671252 | 4 | 0 | 4 |
| BBS12 | ANKRD44 | 0.671124 | 3 | 0 | 3 |
| BBS12 | STARD3NL | 0.670526 | 5 | 0 | 5 |
| BBS12 | PSME1 | 0.668107 | 3 | 0 | 3 |
| BBS12 | RBM7 | 0.667031 | 3 | 0 | 3 |
| BBS12 | RPL41 | 0.66702 | 3 | 0 | 3 |
| BBS12 | MB21D2 | 0.665468 | 3 | 0 | 3 |
For details and further investigation, click here
