| Full name: WD repeat domain 63 | Alias Symbol: DIC3|FLJ30067|NYD-SP29 | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 126820 | HGNC ID: HGNC:30711 | Ensembl Gene: ENSG00000162643 | OMIM ID: 617968 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of WDR63:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR63 | 126820 | 243087_at | -0.1732 | 0.3746 | |
| GSE26886 | WDR63 | 126820 | 243087_at | 0.1236 | 0.2411 | |
| GSE45670 | WDR63 | 126820 | 243087_at | 0.1000 | 0.3588 | |
| GSE53622 | WDR63 | 126820 | 83034 | -0.1665 | 0.1097 | |
| GSE53624 | WDR63 | 126820 | 83034 | -0.2483 | 0.0004 | |
| GSE63941 | WDR63 | 126820 | 243087_at | -2.5381 | 0.0000 | |
| GSE77861 | WDR63 | 126820 | 243087_at | -0.0280 | 0.8104 | |
| TCGA | WDR63 | 126820 | RNAseq | -0.2857 | 0.5771 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WDR63 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR63:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR63 | 126820 | 0 | 8 | 22 | |
| GSE20123 | WDR63 | 126820 | 0 | 8 | 22 | |
| GSE43470 | WDR63 | 126820 | 2 | 2 | 39 | |
| GSE46452 | WDR63 | 126820 | 0 | 1 | 58 | |
| GSE47630 | WDR63 | 126820 | 8 | 5 | 27 | |
| GSE54993 | WDR63 | 126820 | 0 | 0 | 70 | |
| GSE54994 | WDR63 | 126820 | 6 | 3 | 44 | |
| GSE60625 | WDR63 | 126820 | 0 | 0 | 11 | |
| GSE74703 | WDR63 | 126820 | 1 | 2 | 33 | |
| GSE74704 | WDR63 | 126820 | 0 | 5 | 15 | |
| TCGA | WDR63 | 126820 | 7 | 23 | 66 |
Total number of gains: 24; Total number of losses: 57; Total Number of normals: 407.
Somatic mutations of WDR63:
Generating mutation plots.
Highly correlated genes for WDR63:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR63 | DIXDC1 | 0.777683 | 3 | 0 | 3 |
| WDR63 | CNTN4 | 0.7405 | 3 | 0 | 3 |
| WDR63 | PRICKLE2 | 0.73602 | 3 | 0 | 3 |
| WDR63 | NAALADL1 | 0.703395 | 3 | 0 | 3 |
| WDR63 | DGKI | 0.70055 | 3 | 0 | 3 |
| WDR63 | C1QTNF2 | 0.68557 | 3 | 0 | 3 |
| WDR63 | C16orf86 | 0.683538 | 3 | 0 | 3 |
| WDR63 | KRTAP1-5 | 0.678734 | 3 | 0 | 3 |
| WDR63 | CDK15 | 0.673102 | 4 | 0 | 3 |
| WDR63 | COLEC12 | 0.67103 | 4 | 0 | 3 |
| WDR63 | AKAP12 | 0.670076 | 3 | 0 | 3 |
| WDR63 | ACSS3 | 0.658858 | 3 | 0 | 3 |
| WDR63 | DENND2A | 0.657197 | 3 | 0 | 3 |
| WDR63 | GVQW1 | 0.656196 | 3 | 0 | 3 |
| WDR63 | FBXL13 | 0.654934 | 3 | 0 | 3 |
| WDR63 | SMIM10 | 0.648293 | 4 | 0 | 3 |
| WDR63 | MAMDC2 | 0.6347 | 3 | 0 | 3 |
| WDR63 | LINC01140 | 0.632733 | 4 | 0 | 3 |
| WDR63 | TSHZ3 | 0.626198 | 4 | 0 | 3 |
| WDR63 | CYS1 | 0.624853 | 3 | 0 | 3 |
For details and further investigation, click here
