| Full name: formimidoyltransferase cyclodeaminase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 10841 | HGNC ID: HGNC:3974 | Ensembl Gene: ENSG00000160282 | OMIM ID: 606806 |
| Drug and gene relationship at DGIdb | |||
Expression of FTCD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FTCD | 10841 | 223979_x_at | -0.0522 | 0.8878 | |
| GSE20347 | FTCD | 10841 | 220604_x_at | -0.1512 | 0.0681 | |
| GSE23400 | FTCD | 10841 | 220604_x_at | -0.2166 | 0.0001 | |
| GSE26886 | FTCD | 10841 | 223979_x_at | -0.0670 | 0.6653 | |
| GSE29001 | FTCD | 10841 | 220604_x_at | -0.2251 | 0.0292 | |
| GSE38129 | FTCD | 10841 | 220604_x_at | -0.2086 | 0.0486 | |
| GSE45670 | FTCD | 10841 | 233741_at | 0.0654 | 0.4181 | |
| GSE53622 | FTCD | 10841 | 10284 | -0.4466 | 0.0000 | |
| GSE53624 | FTCD | 10841 | 10284 | -1.5616 | 0.0000 | |
| GSE63941 | FTCD | 10841 | 224300_x_at | 0.0800 | 0.6860 | |
| GSE77861 | FTCD | 10841 | 224300_x_at | -0.2190 | 0.1253 | |
| GSE97050 | FTCD | 10841 | A_23_P91552 | -0.0658 | 0.8248 | |
| TCGA | FTCD | 10841 | RNAseq | 0.7043 | 0.3778 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FTCD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FTCD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FTCD | 10841 | 3 | 9 | 18 | |
| GSE20123 | FTCD | 10841 | 3 | 9 | 18 | |
| GSE43470 | FTCD | 10841 | 0 | 14 | 29 | |
| GSE46452 | FTCD | 10841 | 1 | 21 | 37 | |
| GSE47630 | FTCD | 10841 | 6 | 17 | 17 | |
| GSE54993 | FTCD | 10841 | 8 | 1 | 61 | |
| GSE54994 | FTCD | 10841 | 5 | 8 | 40 | |
| GSE60625 | FTCD | 10841 | 0 | 0 | 11 | |
| GSE74703 | FTCD | 10841 | 0 | 10 | 26 | |
| GSE74704 | FTCD | 10841 | 1 | 5 | 14 | |
| TCGA | FTCD | 10841 | 10 | 38 | 48 |
Total number of gains: 37; Total number of losses: 132; Total Number of normals: 319.
Somatic mutations of FTCD:
Generating mutation plots.
Highly correlated genes for FTCD:
Showing top 20/797 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FTCD | FAM163B | 0.778062 | 3 | 0 | 3 |
| FTCD | BARHL2 | 0.772824 | 3 | 0 | 3 |
| FTCD | SLC25A48 | 0.759243 | 3 | 0 | 3 |
| FTCD | TEN1 | 0.757455 | 3 | 0 | 3 |
| FTCD | SLC19A3 | 0.74684 | 4 | 0 | 4 |
| FTCD | KRTAP20-1 | 0.732225 | 3 | 0 | 3 |
| FTCD | KRTAP5-4 | 0.731454 | 3 | 0 | 3 |
| FTCD | CABP7 | 0.730135 | 3 | 0 | 3 |
| FTCD | OR2Z1 | 0.729995 | 3 | 0 | 3 |
| FTCD | KCNA7 | 0.720186 | 3 | 0 | 3 |
| FTCD | CD164L2 | 0.717698 | 3 | 0 | 3 |
| FTCD | MFSD2B | 0.712273 | 3 | 0 | 3 |
| FTCD | LINC00112 | 0.710183 | 3 | 0 | 3 |
| FTCD | OR10G3 | 0.708633 | 3 | 0 | 3 |
| FTCD | BTBD19 | 0.706932 | 4 | 0 | 4 |
| FTCD | SLC5A10 | 0.701316 | 3 | 0 | 3 |
| FTCD | KLF17 | 0.700208 | 3 | 0 | 3 |
| FTCD | RHBG | 0.696692 | 6 | 0 | 5 |
| FTCD | CLRN2 | 0.693215 | 3 | 0 | 3 |
| FTCD | ABCC8 | 0.692118 | 7 | 0 | 6 |
For details and further investigation, click here
