| Full name: keratin associated protein 5-4 | Alias Symbol: KRTAP5.4 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 387267 | HGNC ID: HGNC:23599 | Ensembl Gene: ENSG00000241598 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP5-4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP5-4 | 387267 | 53107 | -0.4972 | 0.0000 | |
| GSE53624 | KRTAP5-4 | 387267 | 53107 | -1.7178 | 0.0000 | |
| GSE97050 | KRTAP5-4 | 387267 | A_33_P3317317 | -0.0140 | 0.9551 | |
| TCGA | KRTAP5-4 | 387267 | RNAseq | 1.0342 | 0.6102 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRTAP5-4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP5-4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP5-4 | 387267 | 1 | 11 | 18 | |
| GSE20123 | KRTAP5-4 | 387267 | 1 | 12 | 17 | |
| GSE43470 | KRTAP5-4 | 387267 | 1 | 9 | 33 | |
| GSE46452 | KRTAP5-4 | 387267 | 7 | 8 | 44 | |
| GSE47630 | KRTAP5-4 | 387267 | 4 | 12 | 24 | |
| GSE54993 | KRTAP5-4 | 387267 | 3 | 1 | 66 | |
| GSE54994 | KRTAP5-4 | 387267 | 1 | 12 | 40 | |
| GSE60625 | KRTAP5-4 | 387267 | 0 | 0 | 11 | |
| GSE74703 | KRTAP5-4 | 387267 | 1 | 7 | 28 | |
| GSE74704 | KRTAP5-4 | 387267 | 0 | 8 | 12 |
Total number of gains: 19; Total number of losses: 80; Total Number of normals: 293.
Somatic mutations of KRTAP5-4:
Generating mutation plots.
Highly correlated genes for KRTAP5-4:
Showing top 20/122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP5-4 | GPR62 | 0.903659 | 3 | 0 | 3 |
| KRTAP5-4 | KRTAP5-11 | 0.857766 | 3 | 0 | 3 |
| KRTAP5-4 | GPHB5 | 0.799871 | 3 | 0 | 3 |
| KRTAP5-4 | ATP2B3 | 0.796982 | 3 | 0 | 3 |
| KRTAP5-4 | KRTAP10-8 | 0.795436 | 3 | 0 | 3 |
| KRTAP5-4 | KRTAP5-5 | 0.793517 | 3 | 0 | 3 |
| KRTAP5-4 | BARHL2 | 0.793308 | 3 | 0 | 3 |
| KRTAP5-4 | RNF222 | 0.791895 | 3 | 0 | 3 |
| KRTAP5-4 | CLEC18C | 0.790328 | 3 | 0 | 3 |
| KRTAP5-4 | HAMP | 0.781588 | 3 | 0 | 3 |
| KRTAP5-4 | NHLRC4 | 0.76906 | 3 | 0 | 3 |
| KRTAP5-4 | IL37 | 0.767548 | 3 | 0 | 3 |
| KRTAP5-4 | DCD | 0.756717 | 3 | 0 | 3 |
| KRTAP5-4 | KRTAP4-1 | 0.753388 | 3 | 0 | 3 |
| KRTAP5-4 | ITGB1BP2 | 0.749504 | 3 | 0 | 3 |
| KRTAP5-4 | KLK2 | 0.743777 | 3 | 0 | 3 |
| KRTAP5-4 | OTOF | 0.738721 | 3 | 0 | 3 |
| KRTAP5-4 | FAM163B | 0.737841 | 3 | 0 | 3 |
| KRTAP5-4 | MFSD2B | 0.731605 | 3 | 0 | 3 |
| KRTAP5-4 | FTCD | 0.731454 | 3 | 0 | 3 |
For details and further investigation, click here
