| Full name: TEN1 subunit of CST complex | Alias Symbol: FLJ39785 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 100134934 | HGNC ID: HGNC:37242 | Ensembl Gene: ENSG00000257949 | OMIM ID: 613130 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TEN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TEN1 | 100134934 | 132045 | -0.3668 | 0.0000 | |
| GSE53624 | TEN1 | 100134934 | 132045 | -0.6370 | 0.0000 | |
| GSE97050 | TEN1 | 100134934 | A_33_P3337491 | -0.1233 | 0.5920 | |
| SRP007169 | TEN1 | 100134934 | RNAseq | -1.7355 | 0.0005 | |
| SRP008496 | TEN1 | 100134934 | RNAseq | -1.9311 | 0.0000 | |
| SRP064894 | TEN1 | 100134934 | RNAseq | -0.2965 | 0.4016 | |
| SRP133303 | TEN1 | 100134934 | RNAseq | -0.0266 | 0.9336 | |
| SRP159526 | TEN1 | 100134934 | RNAseq | -0.9354 | 0.0000 | |
| SRP193095 | TEN1 | 100134934 | RNAseq | -1.0394 | 0.0000 | |
| SRP219564 | TEN1 | 100134934 | RNAseq | -0.8407 | 0.0784 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TEN1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TEN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TEN1 | 100134934 | 7 | 2 | 21 | |
| GSE20123 | TEN1 | 100134934 | 7 | 2 | 21 | |
| GSE43470 | TEN1 | 100134934 | 5 | 3 | 35 | |
| GSE46452 | TEN1 | 100134934 | 34 | 0 | 25 | |
| GSE47630 | TEN1 | 100134934 | 8 | 1 | 31 | |
| GSE54993 | TEN1 | 100134934 | 2 | 5 | 63 | |
| GSE54994 | TEN1 | 100134934 | 10 | 4 | 39 | |
| GSE60625 | TEN1 | 100134934 | 6 | 0 | 5 | |
| GSE74703 | TEN1 | 100134934 | 5 | 1 | 30 | |
| GSE74704 | TEN1 | 100134934 | 5 | 1 | 14 | |
| TCGA | TEN1 | 100134934 | 31 | 10 | 55 |
Total number of gains: 120; Total number of losses: 29; Total Number of normals: 339.
Somatic mutations of TEN1:
Generating mutation plots.
Highly correlated genes for TEN1:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TEN1 | GGT6 | 0.861024 | 3 | 0 | 3 |
| TEN1 | FAM163B | 0.842054 | 3 | 0 | 3 |
| TEN1 | PTK6 | 0.835969 | 3 | 0 | 3 |
| TEN1 | MFSD2B | 0.82599 | 3 | 0 | 3 |
| TEN1 | CD164L2 | 0.819122 | 3 | 0 | 3 |
| TEN1 | EPS8L2 | 0.818418 | 3 | 0 | 3 |
| TEN1 | RRP1 | 0.814137 | 3 | 0 | 3 |
| TEN1 | TMEM125 | 0.805217 | 3 | 0 | 3 |
| TEN1 | OR10G8 | 0.80304 | 3 | 0 | 3 |
| TEN1 | KRTAP20-1 | 0.800159 | 3 | 0 | 3 |
| TEN1 | ERBB2 | 0.796585 | 3 | 0 | 3 |
| TEN1 | PKD2L1 | 0.793613 | 3 | 0 | 3 |
| TEN1 | CSTL1 | 0.791293 | 3 | 0 | 3 |
| TEN1 | KRTAP4-1 | 0.790766 | 3 | 0 | 3 |
| TEN1 | RNF151 | 0.790559 | 3 | 0 | 3 |
| TEN1 | NANOS2 | 0.787898 | 3 | 0 | 3 |
| TEN1 | PCDH1 | 0.787663 | 3 | 0 | 3 |
| TEN1 | PHLDB3 | 0.786283 | 3 | 0 | 3 |
| TEN1 | OTOF | 0.785642 | 3 | 0 | 3 |
| TEN1 | OR2Z1 | 0.785115 | 3 | 0 | 3 |
For details and further investigation, click here
