| Full name: olfactory receptor family 2 subfamily Z member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 284383 | HGNC ID: HGNC:15391 | Ensembl Gene: ENSG00000181733 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR2Z1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR2Z1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR2Z1 | 284383 | 92354 | -1.8165 | 0.0000 | |
| GSE53624 | OR2Z1 | 284383 | 92354 | -1.5759 | 0.0000 | |
| GSE97050 | OR2Z1 | 284383 | A_33_P3227706 | -0.7797 | 0.1963 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by OR2Z1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR2Z1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR2Z1 | 284383 | 4 | 3 | 23 | |
| GSE20123 | OR2Z1 | 284383 | 3 | 2 | 25 | |
| GSE43470 | OR2Z1 | 284383 | 2 | 5 | 36 | |
| GSE46452 | OR2Z1 | 284383 | 47 | 1 | 11 | |
| GSE47630 | OR2Z1 | 284383 | 5 | 7 | 28 | |
| GSE54993 | OR2Z1 | 284383 | 16 | 2 | 52 | |
| GSE54994 | OR2Z1 | 284383 | 6 | 14 | 33 | |
| GSE60625 | OR2Z1 | 284383 | 9 | 0 | 2 | |
| GSE74703 | OR2Z1 | 284383 | 2 | 4 | 30 | |
| GSE74704 | OR2Z1 | 284383 | 0 | 2 | 18 | |
| TCGA | OR2Z1 | 284383 | 10 | 19 | 67 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of OR2Z1:
Generating mutation plots.
Highly correlated genes for OR2Z1:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR2Z1 | KRTAP20-1 | 0.936138 | 3 | 0 | 3 |
| OR2Z1 | UPB1 | 0.923108 | 3 | 0 | 3 |
| OR2Z1 | RRP1 | 0.921051 | 3 | 0 | 3 |
| OR2Z1 | MFSD2B | 0.904361 | 3 | 0 | 3 |
| OR2Z1 | OTOF | 0.898441 | 3 | 0 | 3 |
| OR2Z1 | CSTL1 | 0.898183 | 3 | 0 | 3 |
| OR2Z1 | NCR1 | 0.893629 | 3 | 0 | 3 |
| OR2Z1 | OR10G8 | 0.886147 | 3 | 0 | 3 |
| OR2Z1 | GALNT9 | 0.885894 | 3 | 0 | 3 |
| OR2Z1 | NANOS2 | 0.875419 | 3 | 0 | 3 |
| OR2Z1 | MORN3 | 0.866397 | 3 | 0 | 3 |
| OR2Z1 | PTK6 | 0.862143 | 3 | 0 | 3 |
| OR2Z1 | KLKB1 | 0.861764 | 3 | 0 | 3 |
| OR2Z1 | CLDN24 | 0.849989 | 3 | 0 | 3 |
| OR2Z1 | EPS8L2 | 0.846199 | 3 | 0 | 3 |
| OR2Z1 | FAM163B | 0.843256 | 3 | 0 | 3 |
| OR2Z1 | KLHL10 | 0.833999 | 3 | 0 | 3 |
| OR2Z1 | FGF5 | 0.831409 | 3 | 0 | 3 |
| OR2Z1 | BARHL2 | 0.83091 | 3 | 0 | 3 |
| OR2Z1 | IQCF1 | 0.829459 | 3 | 0 | 3 |
For details and further investigation, click here
