| Full name: potassium voltage-gated channel subfamily A member 7 | Alias Symbol: Kv1.7|HAK6 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 3743 | HGNC ID: HGNC:6226 | Ensembl Gene: ENSG00000104848 | OMIM ID: 176268 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNA7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNA7 | 3743 | 232936_at | -0.0629 | 0.7287 | |
| GSE26886 | KCNA7 | 3743 | 232936_at | 0.0997 | 0.3268 | |
| GSE45670 | KCNA7 | 3743 | 232936_at | -0.0166 | 0.8612 | |
| GSE53622 | KCNA7 | 3743 | 50522 | -1.8698 | 0.0000 | |
| GSE53624 | KCNA7 | 3743 | 50522 | -2.3290 | 0.0000 | |
| GSE63941 | KCNA7 | 3743 | 232936_at | 0.0757 | 0.5633 | |
| GSE77861 | KCNA7 | 3743 | 232936_at | -0.0687 | 0.3777 | |
| GSE97050 | KCNA7 | 3743 | A_23_P164897 | -0.3992 | 0.3023 | |
| SRP064894 | KCNA7 | 3743 | RNAseq | 1.3591 | 0.0000 | |
| SRP133303 | KCNA7 | 3743 | RNAseq | 0.2535 | 0.0264 | |
| SRP159526 | KCNA7 | 3743 | RNAseq | 0.6118 | 0.3138 | |
| SRP193095 | KCNA7 | 3743 | RNAseq | 0.2529 | 0.0736 | |
| SRP219564 | KCNA7 | 3743 | RNAseq | 0.6366 | 0.2792 | |
| TCGA | KCNA7 | 3743 | RNAseq | 2.5854 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by KCNA7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNA7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNA7 | 3743 | 4 | 4 | 22 | |
| GSE20123 | KCNA7 | 3743 | 4 | 3 | 23 | |
| GSE43470 | KCNA7 | 3743 | 4 | 10 | 29 | |
| GSE46452 | KCNA7 | 3743 | 45 | 1 | 13 | |
| GSE47630 | KCNA7 | 3743 | 9 | 6 | 25 | |
| GSE54993 | KCNA7 | 3743 | 17 | 4 | 49 | |
| GSE54994 | KCNA7 | 3743 | 4 | 14 | 35 | |
| GSE60625 | KCNA7 | 3743 | 9 | 0 | 2 | |
| GSE74703 | KCNA7 | 3743 | 4 | 7 | 25 | |
| GSE74704 | KCNA7 | 3743 | 4 | 1 | 15 | |
| TCGA | KCNA7 | 3743 | 14 | 18 | 64 |
Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.
Somatic mutations of KCNA7:
Generating mutation plots.
Highly correlated genes for KCNA7:
Showing top 20/499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNA7 | BARHL2 | 0.901446 | 3 | 0 | 3 |
| KCNA7 | NOTO | 0.870069 | 3 | 0 | 3 |
| KCNA7 | RNF222 | 0.852095 | 3 | 0 | 3 |
| KCNA7 | FAM163B | 0.830344 | 3 | 0 | 3 |
| KCNA7 | KRTAP20-1 | 0.829393 | 3 | 0 | 3 |
| KCNA7 | MAFG | 0.825008 | 3 | 0 | 3 |
| KCNA7 | MFSD2B | 0.820941 | 3 | 0 | 3 |
| KCNA7 | CLEC18C | 0.816553 | 3 | 0 | 3 |
| KCNA7 | KPRP | 0.79929 | 3 | 0 | 3 |
| KCNA7 | GPR62 | 0.796612 | 4 | 0 | 4 |
| KCNA7 | MYO18B | 0.795371 | 3 | 0 | 3 |
| KCNA7 | C10orf90 | 0.793051 | 3 | 0 | 3 |
| KCNA7 | OTOP3 | 0.792634 | 3 | 0 | 3 |
| KCNA7 | PTK6 | 0.788159 | 4 | 0 | 4 |
| KCNA7 | FBXO34 | 0.787633 | 3 | 0 | 3 |
| KCNA7 | NCCRP1 | 0.787403 | 3 | 0 | 3 |
| KCNA7 | S100A9 | 0.785167 | 3 | 0 | 3 |
| KCNA7 | OR2Z1 | 0.780094 | 4 | 0 | 4 |
| KCNA7 | S100A8 | 0.779416 | 3 | 0 | 3 |
| KCNA7 | SPRR2F | 0.77755 | 3 | 0 | 3 |
For details and further investigation, click here
