| Full name: major facilitator superfamily domain containing 2B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 388931 | HGNC ID: HGNC:37207 | Ensembl Gene: ENSG00000205639 | OMIM ID: 617845 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MFSD2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | MFSD2B | 388931 | 80912 | -1.1597 | 0.0000 | |
| GSE53624 | MFSD2B | 388931 | 80912 | -1.1474 | 0.0000 | |
| GSE97050 | MFSD2B | 388931 | A_33_P3398693 | -0.3617 | 0.5006 | |
| SRP133303 | MFSD2B | 388931 | RNAseq | -0.0672 | 0.7313 | |
| TCGA | MFSD2B | 388931 | RNAseq | 1.2887 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by MFSD2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD2B | 388931 | 10 | 2 | 18 | |
| GSE20123 | MFSD2B | 388931 | 10 | 2 | 18 | |
| GSE43470 | MFSD2B | 388931 | 2 | 1 | 40 | |
| GSE46452 | MFSD2B | 388931 | 3 | 4 | 52 | |
| GSE47630 | MFSD2B | 388931 | 8 | 0 | 32 | |
| GSE54993 | MFSD2B | 388931 | 0 | 7 | 63 | |
| GSE54994 | MFSD2B | 388931 | 10 | 0 | 43 | |
| GSE60625 | MFSD2B | 388931 | 0 | 3 | 8 | |
| GSE74703 | MFSD2B | 388931 | 2 | 0 | 34 | |
| GSE74704 | MFSD2B | 388931 | 9 | 1 | 10 | |
| TCGA | MFSD2B | 388931 | 36 | 4 | 56 |
Total number of gains: 90; Total number of losses: 24; Total Number of normals: 374.
Somatic mutations of MFSD2B:
Generating mutation plots.
Highly correlated genes for MFSD2B:
Showing top 20/375 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD2B | KRTAP20-1 | 0.915587 | 3 | 0 | 3 |
| MFSD2B | RRP1 | 0.905391 | 3 | 0 | 3 |
| MFSD2B | OR2Z1 | 0.904361 | 3 | 0 | 3 |
| MFSD2B | PTK6 | 0.891483 | 3 | 0 | 3 |
| MFSD2B | PLEKHN1 | 0.891411 | 3 | 0 | 3 |
| MFSD2B | UPB1 | 0.875802 | 3 | 0 | 3 |
| MFSD2B | FAM163B | 0.871976 | 3 | 0 | 3 |
| MFSD2B | GALNT9 | 0.869514 | 3 | 0 | 3 |
| MFSD2B | NCR1 | 0.866561 | 3 | 0 | 3 |
| MFSD2B | GGT6 | 0.864921 | 3 | 0 | 3 |
| MFSD2B | CSTL1 | 0.861968 | 3 | 0 | 3 |
| MFSD2B | CD164L2 | 0.853113 | 3 | 0 | 3 |
| MFSD2B | ACER1 | 0.850024 | 3 | 0 | 3 |
| MFSD2B | SLC13A4 | 0.845592 | 3 | 0 | 3 |
| MFSD2B | MUC22 | 0.845262 | 3 | 0 | 3 |
| MFSD2B | MORN3 | 0.843064 | 3 | 0 | 3 |
| MFSD2B | RAET1E | 0.842565 | 3 | 0 | 3 |
| MFSD2B | MAST4 | 0.841512 | 3 | 0 | 3 |
| MFSD2B | AIF1L | 0.840797 | 3 | 0 | 3 |
| MFSD2B | MAP3K10 | 0.837052 | 3 | 0 | 3 |
For details and further investigation, click here
