| Full name: general transcription factor IIF subunit 1 | Alias Symbol: TFIIF|BTF4|RAP74|TF2F1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 2962 | HGNC ID: HGNC:4652 | Ensembl Gene: ENSG00000125651 | OMIM ID: 189968 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GTF2F1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2F1 | 2962 | 202355_s_at | -0.2390 | 0.2865 | |
| GSE20347 | GTF2F1 | 2962 | 202355_s_at | -0.2320 | 0.0526 | |
| GSE23400 | GTF2F1 | 2962 | 202356_s_at | 0.0522 | 0.2205 | |
| GSE26886 | GTF2F1 | 2962 | 202355_s_at | 0.8368 | 0.0023 | |
| GSE29001 | GTF2F1 | 2962 | 202356_s_at | -0.1603 | 0.3608 | |
| GSE38129 | GTF2F1 | 2962 | 202355_s_at | -0.1867 | 0.0976 | |
| GSE45670 | GTF2F1 | 2962 | 202355_s_at | -0.0883 | 0.5596 | |
| GSE53622 | GTF2F1 | 2962 | 24876 | -0.0335 | 0.5047 | |
| GSE53624 | GTF2F1 | 2962 | 24876 | 0.0823 | 0.0820 | |
| GSE63941 | GTF2F1 | 2962 | 202355_s_at | 0.7202 | 0.0315 | |
| GSE77861 | GTF2F1 | 2962 | 202355_s_at | 0.1504 | 0.3055 | |
| GSE97050 | GTF2F1 | 2962 | A_23_P16143 | 0.2361 | 0.4421 | |
| SRP007169 | GTF2F1 | 2962 | RNAseq | 0.4224 | 0.3980 | |
| SRP008496 | GTF2F1 | 2962 | RNAseq | 0.4332 | 0.2148 | |
| SRP064894 | GTF2F1 | 2962 | RNAseq | 0.0078 | 0.9687 | |
| SRP133303 | GTF2F1 | 2962 | RNAseq | -0.2452 | 0.0545 | |
| SRP159526 | GTF2F1 | 2962 | RNAseq | -0.2467 | 0.1647 | |
| SRP193095 | GTF2F1 | 2962 | RNAseq | -0.0397 | 0.7326 | |
| SRP219564 | GTF2F1 | 2962 | RNAseq | -0.2363 | 0.5737 | |
| TCGA | GTF2F1 | 2962 | RNAseq | -0.0087 | 0.8474 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF2F1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2F1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2F1 | 2962 | 5 | 3 | 22 | |
| GSE20123 | GTF2F1 | 2962 | 4 | 2 | 24 | |
| GSE43470 | GTF2F1 | 2962 | 2 | 6 | 35 | |
| GSE46452 | GTF2F1 | 2962 | 47 | 1 | 11 | |
| GSE47630 | GTF2F1 | 2962 | 5 | 7 | 28 | |
| GSE54993 | GTF2F1 | 2962 | 16 | 3 | 51 | |
| GSE54994 | GTF2F1 | 2962 | 6 | 14 | 33 | |
| GSE60625 | GTF2F1 | 2962 | 9 | 0 | 2 | |
| GSE74703 | GTF2F1 | 2962 | 2 | 4 | 30 | |
| GSE74704 | GTF2F1 | 2962 | 1 | 2 | 17 | |
| TCGA | GTF2F1 | 2962 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of GTF2F1:
Generating mutation plots.
Highly correlated genes for GTF2F1:
Showing top 20/267 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2F1 | BEX5 | 0.726265 | 3 | 0 | 3 |
| GTF2F1 | HNRNPAB | 0.713474 | 3 | 0 | 3 |
| GTF2F1 | ZNF266 | 0.710544 | 3 | 0 | 3 |
| GTF2F1 | HNRNPUL2 | 0.703347 | 3 | 0 | 3 |
| GTF2F1 | SNRPD2 | 0.692795 | 3 | 0 | 3 |
| GTF2F1 | ZNF791 | 0.692382 | 3 | 0 | 3 |
| GTF2F1 | ING1 | 0.689989 | 3 | 0 | 3 |
| GTF2F1 | METTL3 | 0.672227 | 3 | 0 | 3 |
| GTF2F1 | ALKBH7 | 0.666505 | 5 | 0 | 4 |
| GTF2F1 | BOD1 | 0.66578 | 4 | 0 | 3 |
| GTF2F1 | ZNF57 | 0.665149 | 3 | 0 | 3 |
| GTF2F1 | LRIG3 | 0.663431 | 3 | 0 | 3 |
| GTF2F1 | HNRNPUL1 | 0.661508 | 3 | 0 | 3 |
| GTF2F1 | MTCH1 | 0.660798 | 4 | 0 | 3 |
| GTF2F1 | CLDN5 | 0.658847 | 3 | 0 | 3 |
| GTF2F1 | CUEDC1 | 0.654627 | 4 | 0 | 3 |
| GTF2F1 | ZNF627 | 0.650536 | 3 | 0 | 3 |
| GTF2F1 | NACC1 | 0.650008 | 3 | 0 | 3 |
| GTF2F1 | HSPA5 | 0.647703 | 3 | 0 | 3 |
| GTF2F1 | EEF1D | 0.645946 | 4 | 0 | 3 |
For details and further investigation, click here
