| Full name: zinc finger protein 57 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126295 | HGNC ID: HGNC:13125 | Ensembl Gene: ENSG00000171970 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF57:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF57 | 126295 | 1554628_at | -0.9370 | 0.1073 | |
| GSE26886 | ZNF57 | 126295 | 1554628_at | 0.0547 | 0.8778 | |
| GSE45670 | ZNF57 | 126295 | 1554628_at | -0.7478 | 0.0002 | |
| GSE53622 | ZNF57 | 126295 | 151870 | -0.8559 | 0.0000 | |
| GSE53624 | ZNF57 | 126295 | 151870 | -1.0190 | 0.0000 | |
| GSE63941 | ZNF57 | 126295 | 1554628_at | 1.3688 | 0.0050 | |
| GSE77861 | ZNF57 | 126295 | 1554628_at | -0.8211 | 0.0380 | |
| GSE97050 | ZNF57 | 126295 | A_23_P39263 | -0.1290 | 0.8375 | |
| SRP007169 | ZNF57 | 126295 | RNAseq | -2.1660 | 0.0001 | |
| SRP064894 | ZNF57 | 126295 | RNAseq | -1.3312 | 0.0000 | |
| SRP133303 | ZNF57 | 126295 | RNAseq | -1.0766 | 0.0002 | |
| SRP159526 | ZNF57 | 126295 | RNAseq | -0.3022 | 0.5656 | |
| SRP193095 | ZNF57 | 126295 | RNAseq | -1.4434 | 0.0000 | |
| SRP219564 | ZNF57 | 126295 | RNAseq | -0.6347 | 0.2821 | |
| TCGA | ZNF57 | 126295 | RNAseq | -0.4824 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by ZNF57 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF57:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF57 | 126295 | 4 | 4 | 22 | |
| GSE20123 | ZNF57 | 126295 | 3 | 4 | 23 | |
| GSE43470 | ZNF57 | 126295 | 1 | 9 | 33 | |
| GSE46452 | ZNF57 | 126295 | 47 | 1 | 11 | |
| GSE47630 | ZNF57 | 126295 | 5 | 7 | 28 | |
| GSE54993 | ZNF57 | 126295 | 16 | 3 | 51 | |
| GSE54994 | ZNF57 | 126295 | 8 | 16 | 29 | |
| GSE60625 | ZNF57 | 126295 | 9 | 0 | 2 | |
| GSE74703 | ZNF57 | 126295 | 1 | 6 | 29 | |
| GSE74704 | ZNF57 | 126295 | 1 | 3 | 16 | |
| TCGA | ZNF57 | 126295 | 7 | 23 | 66 |
Total number of gains: 102; Total number of losses: 76; Total Number of normals: 310.
Somatic mutations of ZNF57:
Generating mutation plots.
Highly correlated genes for ZNF57:
Showing top 20/951 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF57 | DOCK3 | 0.751241 | 3 | 0 | 3 |
| ZNF57 | TSPAN6 | 0.740382 | 5 | 0 | 5 |
| ZNF57 | ZDHHC13 | 0.735991 | 5 | 0 | 5 |
| ZNF57 | VPS4B | 0.735941 | 5 | 0 | 5 |
| ZNF57 | ASCC2 | 0.734112 | 4 | 0 | 3 |
| ZNF57 | NUAK2 | 0.733131 | 3 | 0 | 3 |
| ZNF57 | NIPAL1 | 0.732109 | 3 | 0 | 3 |
| ZNF57 | ELOVL1 | 0.731607 | 3 | 0 | 3 |
| ZNF57 | RAB25 | 0.730665 | 6 | 0 | 6 |
| ZNF57 | TWF1 | 0.730586 | 4 | 0 | 4 |
| ZNF57 | BLNK | 0.729849 | 5 | 0 | 5 |
| ZNF57 | DLG2 | 0.726467 | 5 | 0 | 5 |
| ZNF57 | HOOK2 | 0.72576 | 4 | 0 | 4 |
| ZNF57 | EPGN | 0.724243 | 3 | 0 | 3 |
| ZNF57 | VPS25 | 0.723424 | 4 | 0 | 4 |
| ZNF57 | ARHGAP27 | 0.720515 | 6 | 0 | 6 |
| ZNF57 | KIF21A | 0.716136 | 5 | 0 | 4 |
| ZNF57 | SCAMP2 | 0.71569 | 4 | 0 | 4 |
| ZNF57 | PRRG4 | 0.715534 | 4 | 0 | 4 |
| ZNF57 | GMDS | 0.714452 | 5 | 0 | 5 |
For details and further investigation, click here
