| Full name: leucine rich repeats and immunoglobulin like domains 3 | Alias Symbol: FLJ90440|KIAA3016 | ||
| Type: protein-coding gene | Cytoband: 12q14.1 | ||
| Entrez ID: 121227 | HGNC ID: HGNC:30991 | Ensembl Gene: ENSG00000139263 | OMIM ID: 608870 |
| Drug and gene relationship at DGIdb | |||
Expression of LRIG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRIG3 | 121227 | 226908_at | -0.9127 | 0.0547 | |
| GSE26886 | LRIG3 | 121227 | 226908_at | 0.1283 | 0.7272 | |
| GSE45670 | LRIG3 | 121227 | 226908_at | -0.2013 | 0.3785 | |
| GSE53622 | LRIG3 | 121227 | 4093 | 0.1526 | 0.0624 | |
| GSE53624 | LRIG3 | 121227 | 4093 | 0.0983 | 0.2790 | |
| GSE63941 | LRIG3 | 121227 | 226908_at | -0.2665 | 0.7332 | |
| GSE77861 | LRIG3 | 121227 | 226908_at | 0.4841 | 0.3464 | |
| GSE97050 | LRIG3 | 121227 | A_23_P47885 | 0.2844 | 0.3194 | |
| SRP007169 | LRIG3 | 121227 | RNAseq | -0.1800 | 0.6840 | |
| SRP008496 | LRIG3 | 121227 | RNAseq | -0.2202 | 0.4862 | |
| SRP064894 | LRIG3 | 121227 | RNAseq | 0.0790 | 0.7793 | |
| SRP133303 | LRIG3 | 121227 | RNAseq | -0.1132 | 0.5790 | |
| SRP159526 | LRIG3 | 121227 | RNAseq | 0.0926 | 0.7913 | |
| SRP193095 | LRIG3 | 121227 | RNAseq | -0.3334 | 0.0122 | |
| SRP219564 | LRIG3 | 121227 | RNAseq | 0.1699 | 0.7074 | |
| TCGA | LRIG3 | 121227 | RNAseq | -0.0031 | 0.9625 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRIG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRIG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRIG3 | 121227 | 8 | 0 | 22 | |
| GSE20123 | LRIG3 | 121227 | 8 | 0 | 22 | |
| GSE43470 | LRIG3 | 121227 | 2 | 0 | 41 | |
| GSE46452 | LRIG3 | 121227 | 8 | 1 | 50 | |
| GSE47630 | LRIG3 | 121227 | 10 | 2 | 28 | |
| GSE54993 | LRIG3 | 121227 | 0 | 5 | 65 | |
| GSE54994 | LRIG3 | 121227 | 5 | 1 | 47 | |
| GSE60625 | LRIG3 | 121227 | 0 | 0 | 11 | |
| GSE74703 | LRIG3 | 121227 | 2 | 0 | 34 | |
| GSE74704 | LRIG3 | 121227 | 4 | 0 | 16 | |
| TCGA | LRIG3 | 121227 | 17 | 10 | 69 |
Total number of gains: 64; Total number of losses: 19; Total Number of normals: 405.
Somatic mutations of LRIG3:
Generating mutation plots.
Highly correlated genes for LRIG3:
Showing top 20/164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRIG3 | C1D | 0.814736 | 3 | 0 | 3 |
| LRIG3 | DTWD1 | 0.799245 | 3 | 0 | 3 |
| LRIG3 | COIL | 0.765186 | 3 | 0 | 3 |
| LRIG3 | ZNF510 | 0.75903 | 3 | 0 | 3 |
| LRIG3 | USP8 | 0.753131 | 4 | 0 | 3 |
| LRIG3 | FGD4 | 0.74578 | 3 | 0 | 3 |
| LRIG3 | RBAK | 0.739711 | 3 | 0 | 3 |
| LRIG3 | RTN4IP1 | 0.736294 | 3 | 0 | 3 |
| LRIG3 | COMMD1 | 0.731571 | 3 | 0 | 3 |
| LRIG3 | GTF2A2 | 0.731512 | 3 | 0 | 3 |
| LRIG3 | ASCC3 | 0.727888 | 3 | 0 | 3 |
| LRIG3 | TOM1L1 | 0.725186 | 3 | 0 | 3 |
| LRIG3 | ELP3 | 0.714539 | 3 | 0 | 3 |
| LRIG3 | PRPSAP1 | 0.712973 | 3 | 0 | 3 |
| LRIG3 | SLITRK4 | 0.712348 | 3 | 0 | 3 |
| LRIG3 | RPS6KB1 | 0.711175 | 3 | 0 | 3 |
| LRIG3 | HOOK3 | 0.705912 | 3 | 0 | 3 |
| LRIG3 | TTC17 | 0.700937 | 3 | 0 | 3 |
| LRIG3 | XRCC5 | 0.699928 | 3 | 0 | 3 |
| LRIG3 | NPAT | 0.699567 | 3 | 0 | 3 |
For details and further investigation, click here
