| Full name: inhibitor of growth family member 1 | Alias Symbol: p33ING1|p33ING1b|p24ING1c|p33|p47|p47ING1a | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 3621 | HGNC ID: HGNC:6062 | Ensembl Gene: ENSG00000153487 | OMIM ID: 601566 |
| Drug and gene relationship at DGIdb | |||
Expression of ING1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ING1 | 3621 | 208415_x_at | 0.0139 | 0.9767 | |
| GSE20347 | ING1 | 3621 | 208415_x_at | 0.5668 | 0.0273 | |
| GSE23400 | ING1 | 3621 | 208415_x_at | 0.2808 | 0.0000 | |
| GSE26886 | ING1 | 3621 | 208415_x_at | 0.8788 | 0.0003 | |
| GSE29001 | ING1 | 3621 | 208415_x_at | 0.2682 | 0.1969 | |
| GSE38129 | ING1 | 3621 | 208415_x_at | 0.3370 | 0.0468 | |
| GSE45670 | ING1 | 3621 | 208415_x_at | 0.0855 | 0.5762 | |
| GSE53622 | ING1 | 3621 | 106101 | 0.3654 | 0.0005 | |
| GSE53624 | ING1 | 3621 | 106101 | 0.4317 | 0.0000 | |
| GSE63941 | ING1 | 3621 | 208415_x_at | 0.1217 | 0.7645 | |
| GSE77861 | ING1 | 3621 | 208415_x_at | 0.3624 | 0.0693 | |
| GSE97050 | ING1 | 3621 | A_24_P39211 | 0.0870 | 0.7450 | |
| SRP007169 | ING1 | 3621 | RNAseq | 0.2186 | 0.7156 | |
| SRP008496 | ING1 | 3621 | RNAseq | 0.8227 | 0.1210 | |
| SRP064894 | ING1 | 3621 | RNAseq | 0.2751 | 0.0844 | |
| SRP133303 | ING1 | 3621 | RNAseq | 0.2693 | 0.0270 | |
| SRP159526 | ING1 | 3621 | RNAseq | 0.3302 | 0.1890 | |
| SRP193095 | ING1 | 3621 | RNAseq | 0.0070 | 0.9523 | |
| SRP219564 | ING1 | 3621 | RNAseq | 0.5945 | 0.0956 | |
| TCGA | ING1 | 3621 | RNAseq | 0.0433 | 0.4603 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ING1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ING1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ING1 | 3621 | 6 | 11 | 13 | |
| GSE20123 | ING1 | 3621 | 6 | 10 | 14 | |
| GSE43470 | ING1 | 3621 | 4 | 13 | 26 | |
| GSE46452 | ING1 | 3621 | 2 | 31 | 26 | |
| GSE47630 | ING1 | 3621 | 3 | 26 | 11 | |
| GSE54993 | ING1 | 3621 | 11 | 4 | 55 | |
| GSE54994 | ING1 | 3621 | 8 | 8 | 37 | |
| GSE60625 | ING1 | 3621 | 0 | 3 | 8 | |
| GSE74703 | ING1 | 3621 | 3 | 9 | 24 | |
| GSE74704 | ING1 | 3621 | 4 | 9 | 7 | |
| TCGA | ING1 | 3621 | 19 | 33 | 44 |
Total number of gains: 66; Total number of losses: 157; Total Number of normals: 265.
Somatic mutations of ING1:
Generating mutation plots.
Highly correlated genes for ING1:
Showing top 20/1039 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ING1 | ZNF496 | 0.819571 | 3 | 0 | 3 |
| ING1 | CDKN1C | 0.819291 | 3 | 0 | 3 |
| ING1 | ARHGAP24 | 0.766207 | 3 | 0 | 3 |
| ING1 | LONRF3 | 0.761205 | 3 | 0 | 3 |
| ING1 | ZBED1 | 0.750995 | 3 | 0 | 3 |
| ING1 | EDNRB | 0.750423 | 3 | 0 | 3 |
| ING1 | EFEMP2 | 0.747931 | 4 | 0 | 4 |
| ING1 | RASSF8 | 0.746873 | 3 | 0 | 3 |
| ING1 | ERG | 0.742887 | 3 | 0 | 3 |
| ING1 | IWS1 | 0.741984 | 4 | 0 | 4 |
| ING1 | RBM18 | 0.739275 | 3 | 0 | 3 |
| ING1 | OLFML1 | 0.736509 | 3 | 0 | 3 |
| ING1 | PIGL | 0.735187 | 3 | 0 | 3 |
| ING1 | ALKBH6 | 0.735072 | 4 | 0 | 4 |
| ING1 | GAS6 | 0.733729 | 4 | 0 | 4 |
| ING1 | WDR81 | 0.732912 | 3 | 0 | 3 |
| ING1 | GGN | 0.729543 | 3 | 0 | 3 |
| ING1 | BVES | 0.729471 | 3 | 0 | 3 |
| ING1 | SSBP4 | 0.728427 | 4 | 0 | 3 |
| ING1 | LIX1L | 0.726613 | 3 | 0 | 3 |
For details and further investigation, click here
