| Full name: alkB homolog 7 | Alias Symbol: MGC10974 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 84266 | HGNC ID: HGNC:21306 | Ensembl Gene: ENSG00000125652 | OMIM ID: 613305 |
| Drug and gene relationship at DGIdb | |||
Expression of ALKBH7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALKBH7 | 84266 | 223318_s_at | -0.5197 | 0.2333 | |
| GSE26886 | ALKBH7 | 84266 | 227878_s_at | 0.1282 | 0.5740 | |
| GSE45670 | ALKBH7 | 84266 | 223318_s_at | -0.6608 | 0.0021 | |
| GSE53622 | ALKBH7 | 84266 | 105886 | -0.8358 | 0.0000 | |
| GSE53624 | ALKBH7 | 84266 | 105886 | -0.8270 | 0.0000 | |
| GSE63941 | ALKBH7 | 84266 | 223318_s_at | 0.8520 | 0.0496 | |
| GSE77861 | ALKBH7 | 84266 | 223318_s_at | -0.6358 | 0.0132 | |
| GSE97050 | ALKBH7 | 84266 | A_24_P91472 | -0.3577 | 0.1505 | |
| SRP007169 | ALKBH7 | 84266 | RNAseq | -1.8810 | 0.0000 | |
| SRP008496 | ALKBH7 | 84266 | RNAseq | -1.5085 | 0.0000 | |
| SRP064894 | ALKBH7 | 84266 | RNAseq | -0.1039 | 0.8155 | |
| SRP133303 | ALKBH7 | 84266 | RNAseq | -0.8855 | 0.0000 | |
| SRP159526 | ALKBH7 | 84266 | RNAseq | -0.6995 | 0.0343 | |
| SRP193095 | ALKBH7 | 84266 | RNAseq | -1.2765 | 0.0000 | |
| SRP219564 | ALKBH7 | 84266 | RNAseq | -0.8263 | 0.0245 | |
| TCGA | ALKBH7 | 84266 | RNAseq | -0.1766 | 0.0136 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ALKBH7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALKBH7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALKBH7 | 84266 | 5 | 3 | 22 | |
| GSE20123 | ALKBH7 | 84266 | 4 | 2 | 24 | |
| GSE43470 | ALKBH7 | 84266 | 2 | 6 | 35 | |
| GSE46452 | ALKBH7 | 84266 | 47 | 1 | 11 | |
| GSE47630 | ALKBH7 | 84266 | 5 | 7 | 28 | |
| GSE54993 | ALKBH7 | 84266 | 16 | 3 | 51 | |
| GSE54994 | ALKBH7 | 84266 | 6 | 16 | 31 | |
| GSE60625 | ALKBH7 | 84266 | 9 | 0 | 2 | |
| GSE74703 | ALKBH7 | 84266 | 2 | 4 | 30 | |
| GSE74704 | ALKBH7 | 84266 | 1 | 2 | 17 | |
| TCGA | ALKBH7 | 84266 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 63; Total Number of normals: 319.
Somatic mutations of ALKBH7:
Generating mutation plots.
Highly correlated genes for ALKBH7:
Showing top 20/1118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALKBH7 | TBC1D22B | 0.825685 | 3 | 0 | 3 |
| ALKBH7 | KAT5 | 0.811056 | 3 | 0 | 3 |
| ALKBH7 | SH2B1 | 0.809545 | 3 | 0 | 3 |
| ALKBH7 | CLTB | 0.800993 | 3 | 0 | 3 |
| ALKBH7 | DUSP22 | 0.794337 | 5 | 0 | 5 |
| ALKBH7 | RBPJL | 0.794082 | 3 | 0 | 3 |
| ALKBH7 | FBXO10 | 0.793508 | 3 | 0 | 3 |
| ALKBH7 | RC3H1 | 0.790074 | 3 | 0 | 3 |
| ALKBH7 | PPP6C | 0.788679 | 3 | 0 | 3 |
| ALKBH7 | IFT46 | 0.781122 | 3 | 0 | 3 |
| ALKBH7 | COA3 | 0.772588 | 4 | 0 | 4 |
| ALKBH7 | GPD1L | 0.767642 | 6 | 0 | 6 |
| ALKBH7 | APEH | 0.767175 | 4 | 0 | 4 |
| ALKBH7 | FKBPL | 0.765365 | 4 | 0 | 4 |
| ALKBH7 | GRHPR | 0.763359 | 3 | 0 | 3 |
| ALKBH7 | MRPS10 | 0.759377 | 3 | 0 | 3 |
| ALKBH7 | CDK5RAP3 | 0.752438 | 3 | 0 | 3 |
| ALKBH7 | AFF4 | 0.7508 | 3 | 0 | 3 |
| ALKBH7 | HIGD1A | 0.747596 | 4 | 0 | 4 |
| ALKBH7 | AP1B1 | 0.743944 | 4 | 0 | 4 |
For details and further investigation, click here
