| Full name: interleukin 17 receptor E like | Alias Symbol: FLJ41993 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 400935 | HGNC ID: HGNC:33808 | Ensembl Gene: ENSG00000188263 | OMIM ID: 613414 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IL17REL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | IL17REL | 400935 | 13251 | 0.0346 | 0.7014 | |
| GSE53624 | IL17REL | 400935 | 13251 | -0.6684 | 0.0000 | |
| GSE97050 | IL17REL | 400935 | A_33_P3378291 | -0.1001 | 0.6286 | |
| SRP133303 | IL17REL | 400935 | RNAseq | -0.1315 | 0.3104 | |
| SRP193095 | IL17REL | 400935 | RNAseq | -0.5607 | 0.0376 | |
| SRP219564 | IL17REL | 400935 | RNAseq | 0.3271 | 0.4970 | |
| TCGA | IL17REL | 400935 | RNAseq | -1.2932 | 0.0476 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IL17REL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL17REL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL17REL | 400935 | 3 | 8 | 19 | |
| GSE20123 | IL17REL | 400935 | 3 | 8 | 19 | |
| GSE43470 | IL17REL | 400935 | 2 | 8 | 33 | |
| GSE46452 | IL17REL | 400935 | 31 | 2 | 26 | |
| GSE47630 | IL17REL | 400935 | 9 | 4 | 27 | |
| GSE54993 | IL17REL | 400935 | 4 | 6 | 60 | |
| GSE54994 | IL17REL | 400935 | 11 | 8 | 34 | |
| GSE60625 | IL17REL | 400935 | 5 | 0 | 6 | |
| GSE74703 | IL17REL | 400935 | 2 | 6 | 28 | |
| GSE74704 | IL17REL | 400935 | 1 | 4 | 15 | |
| TCGA | IL17REL | 400935 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of IL17REL:
Generating mutation plots.
Highly correlated genes for IL17REL:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL17REL | DYTN | 0.763399 | 3 | 0 | 3 |
| IL17REL | FXYD2 | 0.75512 | 3 | 0 | 3 |
| IL17REL | OR2B11 | 0.754343 | 3 | 0 | 3 |
| IL17REL | ESPNL | 0.75242 | 3 | 0 | 3 |
| IL17REL | TSSK3 | 0.750477 | 3 | 0 | 3 |
| IL17REL | TFE3 | 0.736361 | 3 | 0 | 3 |
| IL17REL | PATE3 | 0.732754 | 3 | 0 | 3 |
| IL17REL | ISLR2 | 0.718652 | 3 | 0 | 3 |
| IL17REL | TERT | 0.715487 | 3 | 0 | 3 |
| IL17REL | GPR173 | 0.713077 | 3 | 0 | 3 |
| IL17REL | TTC7A | 0.709962 | 3 | 0 | 3 |
| IL17REL | GPHB5 | 0.708821 | 3 | 0 | 3 |
| IL17REL | OR7A17 | 0.703588 | 3 | 0 | 3 |
| IL17REL | ZNF182 | 0.692629 | 3 | 0 | 3 |
| IL17REL | KRTAP10-8 | 0.689671 | 3 | 0 | 3 |
| IL17REL | MAMSTR | 0.685775 | 3 | 0 | 3 |
| IL17REL | USHBP1 | 0.684362 | 3 | 0 | 3 |
| IL17REL | FSIP1 | 0.683246 | 3 | 0 | 3 |
| IL17REL | ANKRD33 | 0.682674 | 3 | 0 | 3 |
| IL17REL | MRGPRE | 0.677016 | 3 | 0 | 3 |
For details and further investigation, click here
