| Full name: USH1 protein network component harmonin binding protein 1 | Alias Symbol: MCC2|AIEBP|FLJ38709 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 83878 | HGNC ID: HGNC:24058 | Ensembl Gene: ENSG00000130307 | OMIM ID: 611810 |
| Drug and gene relationship at DGIdb | |||
Expression of USHBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USHBP1 | 83878 | 235510_at | 0.0009 | 0.9979 | |
| GSE26886 | USHBP1 | 83878 | 235510_at | 0.1147 | 0.2963 | |
| GSE45670 | USHBP1 | 83878 | 235510_at | -0.0276 | 0.7873 | |
| GSE53622 | USHBP1 | 83878 | 21228 | -0.1235 | 0.0954 | |
| GSE53624 | USHBP1 | 83878 | 21228 | -0.9871 | 0.0000 | |
| GSE63941 | USHBP1 | 83878 | 235510_at | 0.2542 | 0.2662 | |
| GSE77861 | USHBP1 | 83878 | 235510_at | -0.0465 | 0.8384 | |
| GSE97050 | USHBP1 | 83878 | A_32_P189592 | -0.0598 | 0.8106 | |
| SRP064894 | USHBP1 | 83878 | RNAseq | 0.4866 | 0.1545 | |
| SRP133303 | USHBP1 | 83878 | RNAseq | -0.3686 | 0.0138 | |
| SRP159526 | USHBP1 | 83878 | RNAseq | -0.4638 | 0.3566 | |
| SRP193095 | USHBP1 | 83878 | RNAseq | -0.1140 | 0.4007 | |
| SRP219564 | USHBP1 | 83878 | RNAseq | -0.2182 | 0.7056 | |
| TCGA | USHBP1 | 83878 | RNAseq | -0.9235 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USHBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USHBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USHBP1 | 83878 | 4 | 4 | 22 | |
| GSE20123 | USHBP1 | 83878 | 3 | 2 | 25 | |
| GSE43470 | USHBP1 | 83878 | 2 | 6 | 35 | |
| GSE46452 | USHBP1 | 83878 | 47 | 1 | 11 | |
| GSE47630 | USHBP1 | 83878 | 4 | 8 | 28 | |
| GSE54993 | USHBP1 | 83878 | 15 | 4 | 51 | |
| GSE54994 | USHBP1 | 83878 | 6 | 14 | 33 | |
| GSE60625 | USHBP1 | 83878 | 9 | 0 | 2 | |
| GSE74703 | USHBP1 | 83878 | 2 | 4 | 30 | |
| GSE74704 | USHBP1 | 83878 | 0 | 2 | 18 | |
| TCGA | USHBP1 | 83878 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of USHBP1:
Generating mutation plots.
Highly correlated genes for USHBP1:
Showing top 20/231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USHBP1 | OTUD5 | 0.842292 | 3 | 0 | 3 |
| USHBP1 | DIO3 | 0.795177 | 3 | 0 | 3 |
| USHBP1 | C1QL1 | 0.771557 | 3 | 0 | 3 |
| USHBP1 | TMEM179 | 0.767857 | 3 | 0 | 3 |
| USHBP1 | MIIP | 0.758187 | 3 | 0 | 3 |
| USHBP1 | UMODL1 | 0.751007 | 3 | 0 | 3 |
| USHBP1 | BARHL2 | 0.748533 | 3 | 0 | 3 |
| USHBP1 | PAX3 | 0.74731 | 3 | 0 | 3 |
| USHBP1 | IGSF21 | 0.7464 | 3 | 0 | 3 |
| USHBP1 | TM6SF2 | 0.746338 | 3 | 0 | 3 |
| USHBP1 | C6orf223 | 0.714167 | 3 | 0 | 3 |
| USHBP1 | IQSEC3 | 0.713489 | 3 | 0 | 3 |
| USHBP1 | C9orf106 | 0.713267 | 3 | 0 | 3 |
| USHBP1 | CCDC130 | 0.712006 | 3 | 0 | 3 |
| USHBP1 | AGAP2 | 0.708261 | 3 | 0 | 3 |
| USHBP1 | TMCC2 | 0.70412 | 3 | 0 | 3 |
| USHBP1 | TRIM17 | 0.701513 | 3 | 0 | 3 |
| USHBP1 | TPO | 0.700491 | 4 | 0 | 3 |
| USHBP1 | ESPNL | 0.700329 | 4 | 0 | 4 |
| USHBP1 | PPIL2 | 0.698156 | 3 | 0 | 3 |
For details and further investigation, click here
