ESPNL

 

Full name: espin like Alias Symbol: FLJ42568
Type: protein-coding gene Cytoband: 2q37.3
Entrez ID: 339768 HGNC ID: HGNC:27937 Ensembl Gene: ENSG00000144488 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ESPNL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ESPNL 339768 1557000_at -0.0254 0.9416
GSE26886 ESPNL 339768 1557000_at -0.1133 0.2747
GSE45670 ESPNL 339768 1557000_at 0.0121 0.9061
GSE53622 ESPNL 339768 17150 -0.1550 0.0169
GSE53624 ESPNL 339768 17150 -0.4467 0.0000
GSE63941 ESPNL 339768 1557000_at -0.1211 0.4697
GSE77861 ESPNL 339768 1557002_x_at -0.0223 0.8540
GSE97050 ESPNL 339768 A_33_P3392829 -0.1080 0.6159
SRP219564 ESPNL 339768 RNAseq -0.1612 0.7993
TCGA ESPNL 339768 RNAseq -0.0295 0.9441

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ESPNL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ESPNL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ESPNL 339768 1 12 17
GSE20123 ESPNL 339768 1 12 17
GSE43470 ESPNL 339768 1 9 33
GSE46452 ESPNL 339768 0 5 54
GSE47630 ESPNL 339768 4 5 31
GSE54993 ESPNL 339768 3 2 65
GSE54994 ESPNL 339768 8 10 35
GSE60625 ESPNL 339768 0 3 8
GSE74703 ESPNL 339768 1 7 28
GSE74704 ESPNL 339768 1 5 14
TCGA ESPNL 339768 12 27 57

Total number of gains: 32; Total number of losses: 97; Total Number of normals: 359.  


 

Somatic mutations of ESPNL:

 

Generating mutation plots.

 

Highly correlated genes for ESPNL:

 

Showing top 20/351 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ESPNLPDZRN30.853136303
ESPNLFXYD20.847607303
ESPNLCHMP60.842112303
ESPNLTSSK30.821509404
ESPNLNUDT130.799783303
ESPNLOR2B110.784184303
ESPNLMAPK8IP20.780984303
ESPNLBCKDHA0.780756303
ESPNLPRSS380.774913303
ESPNLLMF10.773673303
ESPNLSCARA50.770881303
ESPNLKRT770.770801303
ESPNLSP60.770395404
ESPNLSLC25A470.758276303
ESPNLFSIP10.757754303
ESPNLCHRD0.757138303
ESPNLINSC0.756972303
ESPNLYY20.753965303
ESPNLTAS2R390.753524303
ESPNLIL17REL0.75242303

For details and further investigation, click here